[Wed Aug 24 18:16:51 2016] >Input file: TM3WVFATD.pdb >TM segments: A332-370_A421-440_A465-478_A509-526 MAIDEN score = -37.3027 Below is the ranking list of the residue pairs and their related pseudo-energy (the lower, the better). This includes inter-chain residue pairs. The maximum (least favorable) pairwise energy value has been set to 10. See the MAIDEN software article: Postic,G., Ghouzam,Y. and Gelly,J.C. (2015) Biochimie, 115, 155–161. ----------- ---------------- Calpha pair Empirical energy ----------- ---------------- L344A-I361A 1.18515047948654 I359A-V519A 1.00893837250984 V351A-F356A 0.943009733510993 F509A-V514A 0.931180857937484 M471A-I518A 0.900685383172592 W334A-A435A 0.823376132937177 L344A-I358A 0.810219060731661 I478A-I525A 0.808243945537763 L344A-W354A 0.79842021692925 T362A-V519A 0.707352750434519 Q338A-M439A 0.675710406681685 F341A-M439A 0.674841288825544 T474A-I518A 0.620715988879762 L436A-L513A 0.609250227460449 H348A-F356A 0.572875463370213 L467A-S511A 0.569628838964927 I358A-Y516A 0.560438017229656 R366A-V523A 0.537849390584934 K345A-W354A 0.537708616428952 L470A-I518A 0.532860303682107 I359A-Y516A 0.517822266638939 L440A-P510A 0.517614775995131 F433A-L513A 0.516374476991111 L467A-V514A 0.505901923241566 F363A-S520A 0.50321332603524 I360A-R366A 0.495837493156387 L333A-P431A 0.490626430359366 R366A-S520A 0.48471819594546 L343A-I361A 0.478750016572632 L467A-L515A 0.470549632484663 Q429A-L434A 0.464217551875427 I359A-L515A 0.457787141078003 F341A-W346A 0.4407729357054 L340A-K345A 0.430111640283132 T474A-L522A 0.427784726796594 L333A-L434A 0.425607787015172 L333A-Y438A 0.424322140837196 S337A-L436A 0.423685130613034 Q338A-L343A 0.417924617069055 I336A-M439A 0.41745217328041 F477A-I525A 0.414415001863008 M471A-N521A 0.414049121858982 W332A-M430A 0.386351790404582 M475A-I525A 0.382696803494831 W346A-V351A 0.381894422526491 L440A-L513A 0.373084965135556 I347A-I360A 0.368657868670605 I478A-N521A 0.363063963970385 Y465A-G512A 0.356605215712417 L440A-G512A 0.354189975537463 W354A-M439A 0.353327989304888 I347A-I361A 0.353109792590805 M471A-Y517A 0.34729260560824 L340A-M439A 0.344354576881838 L344A-S357A 0.343583667025242 M471A-L515A 0.340178626425672 K342A-A435A 0.338912106945705 P468A-N521A 0.335429218482848 P425A-S520A 0.329739831446542 I469A-M475A 0.327221868095709 C423A-I478A 0.31989742767962 I358A-G512A 0.310304824941124 Y465A-V473A 0.304052390930164 V365A-M439A 0.302174230412971 Y438A-V514A 0.299021070959812 M369A-Q429A 0.291295888236663 G355A-L440A 0.289730183981 Y517A-L522A 0.285174850544641 P468A-V514A 0.282922317026093 L344A-G352A 0.282041717282686 I432A-Y437A 0.2784084532971 L340A-L436A 0.275761481408324 Y437A-L513A 0.270969632150781 T362A-Y517A 0.267201268997587 L343A-S357A 0.258299438576444 L440A-S511A 0.256542986541184 T474A-I525A 0.253935065274857 G472A-L522A 0.253672675990297 S337A-L440A 0.249344221759234 M369A-V519A 0.249129745161154 S337A-Y438A 0.24825204055487 T362A-Q429A 0.245696396332138 C423A-I432A 0.244271729495225 I336A-P431A 0.235317991269266 V473A-I525A 0.229967150946686 F433A-G512A 0.227873566773141 S511A-Y516A 0.224191419129673 I478A-T524A 0.223661394960408 I336A-A435A 0.222301472647702 P339A-L440A 0.221264477700479 P425A-Y517A 0.215972979073363 G422A-I428A 0.210983115725986 W334A-I432A 0.209193369237252 P431A-L513A 0.208639623009666 P431A-Y517A 0.207988865652212 G472A-Y516A 0.207949349802004 K342A-I347A 0.206410906964233 Y370A-Q429A 0.205116508334221 I364A-V523A 0.203504586205009 F363A-V523A 0.201660928677899 L467A-N521A 0.200374591506739 P339A-Y437A 0.200341919439099 L426A-N521A 0.199493042935712 P339A-K345A 0.196091561092734 G355A-Y517A 0.192865123737784 N353A-G512A 0.192669144987762 I359A-G512A 0.19137999972161 M430A-S520A 0.186183555021086 S511A-N521A 0.185314990782703 M475A-Y516A 0.185047411419915 P425A-N521A 0.185004912955097 I358A-L515A 0.182309909406063 I336A-I432A 0.181561973282931 Q338A-P431A 0.179899991951543 T362A-A435A 0.179792854887538 L434A-G512A 0.178031262433571 V351A-I361A 0.177844247024536 K342A-L440A 0.172777571597704 Y438A-S511A 0.172333057923393 F363A-V519A 0.170195761276548 K345A-T362A 0.169526785908477 I361A-I518A 0.167613568481582 N521A-I526A 0.167244684656046 T362A-L515A 0.161856042923561 I368A-I432A 0.160479532837782 F363A-T524A 0.160089806228202 F477A-S520A 0.157973165163765 L340A-W346A 0.157959064678281 I364A-V519A 0.156340391300494 M471A-V514A 0.155889699701977 W354A-S511A 0.153515060377961 L426A-M475A 0.153275101784673 K345A-L440A 0.153256370234277 G422A-Q429A 0.152322265203066 I358A-V519A 0.151089602156193 V473A-I518A 0.148408596316612 L467A-I518A 0.147810495001139 W354A-T362A 0.147313287228834 I358A-I432A 0.145146604683366 G472A-L515A 0.142703499798983 Y370A-I526A 0.140183179763477 K342A-L436A 0.138300652120009 M369A-Y516A 0.137962240527673 V365A-I432A 0.13492808052718 P468A-G512A 0.133849396625888 S511A-S520A 0.133034234278105 F356A-S520A 0.132843844387414 I360A-L436A 0.131875589336303 I336A-I428A 0.129611952445502 G367A-T524A 0.129265278908409 M439A-Y517A 0.129181325903499 Y465A-I518A 0.12891930897904 V365A-L436A 0.128578580571734 I364A-L522A 0.128205194827733 Y438A-Y516A 0.127890098846258 I478A-Y517A 0.127589393075963 I432A-L515A 0.127386636067631 Y465A-L513A 0.126946705442644 I360A-V519A 0.125753854339216 L344A-Y437A 0.125105109119358 L440A-Y517A 0.125006984239229 I361A-A435A 0.124877825320307 M369A-Y517A 0.124697183278107 G472A-I525A 0.124218883122147 K345A-G355A 0.121846927618706 L343A-T362A 0.120955179087423 S357A-L440A 0.119547984080118 L340A-L513A 0.119433616543034 S337A-V365A 0.118460291700401 I364A-I432A 0.117752200013321 I364A-Y517A 0.116914896193753 K342A-I358A 0.116243244737084 L343A-L440A 0.115951052308447 L344A-L513A 0.115089791670549 I364A-L436A 0.114553327311526 L343A-L436A 0.113705045211261 L467A-L522A 0.113607080773271 L340A-V365A 0.11326271262107 L333A-L340A 0.112632932881561 L340A-I361A 0.112415593804924 L340A-Y516A 0.112147171422798 I466A-Y517A 0.111724204278419 V351A-I360A 0.111493094249106 S337A-L513A 0.110390049593306 L470A-S511A 0.110225317116721 Y437A-S520A 0.110044256575148 F335A-F433A 0.109856724012742 F341A-Y437A 0.108871437791743 L340A-W354A 0.108624770576837 F335A-Y438A 0.108118175502424 G355A-V519A 0.107508906952883 M439A-V514A 0.106256171902217 G355A-L515A 0.104976112585481 T474A-V514A 0.104921721935251 F433A-N521A 0.104826608017875 Y517A-I526A 0.104824905719316 L340A-Y437A 0.104522289344071 Y370A-I428A 0.104138668122207 A435A-G512A 0.103840761075896 I432A-G512A 0.103337446695903 F335A-K342A 0.102916992441536 P431A-Y516A 0.10212318674297 L434A-P510A 0.100967995880351 S357A-V519A 0.100577623689677 M471A-P510A 0.0999514995485367 L333A-I428A 0.0984613531949385 F335A-Y437A 0.0978743545354579 N353A-T362A 0.0965843087201548 L344A-A435A 0.0963952674394858 L333A-P339A 0.0962387267690473 S511A-V519A 0.0955842569535066 G355A-V514A 0.0947643328907422 L333A-Q338A 0.0940475404487984 I466A-G512A 0.0939088997175928 L426A-I518A 0.0938017842234385 F341A-G355A 0.0937071604815105 Q338A-L434A 0.0933663105056155 I358A-I518A 0.0921318193312866 L434A-L515A 0.0915189047285327 L344A-V365A 0.090907921986831 L333A-Q429A 0.0908917881958331 I336A-I361A 0.0904519744259327 F356A-L522A 0.090013288149966 I361A-V523A 0.0898893956725332 Y437A-Y516A 0.0879209589622887 M430A-L513A 0.0876427940428259 V351A-S357A 0.087630008198194 M471A-T524A 0.0871814264327683 C423A-Q429A 0.0863366812922053 M369A-P431A 0.0862663084557722 I358A-L522A 0.0860867450635077 V365A-L513A 0.0859568201791721 K345A-I358A 0.0856588268972214 S337A-T362A 0.0855688008397635 L344A-Y438A 0.0851091345443038 V365A-I428A 0.0845512026802284 L333A-L440A 0.0842282650621637 G352A-I358A 0.0842121550791504 G367A-V519A 0.0841644032333448 M475A-L515A 0.0841531694558708 I336A-L436A 0.0839335846122271 I359A-L440A 0.0839034562285113 H348A-M439A 0.0836032515060863 T362A-S511A 0.0834667123271945 P339A-I361A 0.0831758391998812 I358A-M439A 0.0828692564536722 I428A-Y517A 0.0827593655759236 L340A-R366A 0.0826059427394661 V365A-A435A 0.082131408796748 S357A-L515A 0.0820018520375472 R366A-P425A 0.0818957558272957 W354A-L515A 0.081716725566551 L333A-L427A 0.0813682202795083 M369A-I432A 0.0805689373209577 L343A-A435A 0.0805661734960887 I358A-L467A 0.0803029692768775 S357A-S520A 0.0800090393672903 Y438A-F509A 0.0798960699555247 L436A-S511A 0.0798489348664497 L440A-L515A 0.079828219161052 M369A-T524A 0.0782140624619403 I469A-L513A 0.0776930465211789 F350A-G355A 0.0772306582152891 F335A-L340A 0.0769873578913423 W334A-Y437A 0.0765226556723428 L343A-M439A 0.0764590576691013 F335A-L344A 0.0759312894691666 S337A-K345A 0.0753024771299975 I359A-I518A 0.0748316759694312 L426A-I478A 0.0747248796585143 S357A-S511A 0.0746389192899377 V473A-L515A 0.0745652166402418 L426A-S520A 0.0736779085009029 I469A-L522A 0.073558938895113 N353A-I358A 0.0735398116641441 S337A-L343A 0.0726421776097155 P425A-L434A 0.0719584582809345 N353A-S511A 0.0718695831122576 W332A-L434A 0.0713199636186044 W346A-G352A 0.0708157941148229 K342A-Y437A 0.0707104692787581 P425A-M475A 0.0703484431047907 L427A-L436A 0.0698081008511995 T362A-V514A 0.0691278147140786 M430A-Y516A 0.0687723348902892 T362A-Y437A 0.0684451816645799 G355A-G512A 0.0675538865636343 I359A-M439A 0.0673890881928179 S337A-I358A 0.0655703472205971 F341A-L434A 0.0633701833765175 K345A-F350A 0.0625579718236264 M475A-L513A 0.0623570844393573 V365A-S520A 0.0618495200586322 L340A-S357A 0.0615621401681228 Q338A-I432A 0.0613684172116269 K345A-I359A 0.0613534684887265 A435A-F509A 0.0611884876969229 F341A-F350A 0.060677083087965 F341A-F363A 0.060677083087965 I469A-Y516A 0.0605924673693492 Q429A-V514A 0.0603171561002358 L436A-L515A 0.0602638650129954 I466A-L513A 0.0587595698367709 S357A-L436A 0.0583431078513232 F341A-W354A 0.0583165945329096 L344A-G512A 0.0580006115400442 P425A-I432A 0.057299727081868 H348A-W354A 0.0567770205428575 F476A-Y517A 0.0566344061660162 F356A-I518A 0.054890668363999 K342A-T362A 0.0539514932854857 S357A-V365A 0.0537292225186015 I336A-Q429A 0.0537183183707941 L343A-I368A 0.0536357296416767 G367A-S520A 0.0533739642749573 I359A-T524A 0.0532074114289261 I428A-L436A 0.0531666945119711 K345A-F356A 0.0529273451774308 I361A-G367A 0.0528971008928085 T362A-I525A 0.0526749629939358 V473A-I526A 0.0525237659068196 L340A-H348A 0.0520207549624919 V365A-Q429A 0.0517889016536555 F335A-L440A 0.0516370584144044 I360A-L513A 0.0515994721199737 L470A-I525A 0.05156866057091 L470A-L513A 0.0510875636152273 I469A-S511A 0.0510259083439699 F363A-N521A 0.0502405865811044 I368A-S520A 0.0500860355135551 S349A-G355A 0.0500007454748896 T474A-L515A 0.0493898934234345 P468A-T474A 0.0492089997445451 L333A-L436A 0.0491027167975506 L436A-G512A 0.0490302811707304 I336A-T362A 0.0483979276715147 G512A-S520A 0.0483872485477104 I359A-N521A 0.0483575426095744 P468A-F477A 0.0483396733430763 A435A-L515A 0.0482196009017493 M369A-F424A 0.0481357456598742 M471A-L522A 0.0480926462136666 V519A-I525A 0.0479074330251237 F363A-L513A 0.0476344593675315 G367A-I526A 0.047363664153167 R366A-F433A 0.0468518738751218 G355A-L467A 0.0459226588659014 I364A-L515A 0.0454884191704616 S337A-G512A 0.0450858245951862 A435A-Y517A 0.04468533063047 T362A-M439A 0.0444939966522346 M471A-I526A 0.0441840459337772 S357A-M439A 0.04406940411287 V473A-S520A 0.0439919441584951 L340A-I368A 0.0439151841377354 G472A-S520A 0.0437514249852675 S337A-Q429A 0.0435829306268118 W354A-L436A 0.0431044367885276 I336A-M369A 0.0429357603837879 I336A-L434A 0.0424153597240009 V365A-Y517A 0.0421184046145324 F477A-V519A 0.0420912250444831 Q429A-L513A 0.0420222852097885 W346A-F363A 0.0418647939160202 F341A-G512A 0.0409705442500021 L470A-G512A 0.0408554064635442 M369A-F433A 0.0407572493584234 M475A-N521A 0.0406490529828245 I358A-R366A 0.0405889005552784 K342A-W354A 0.040147803707236 F356A-V514A 0.0400443790659523 I361A-V514A 0.0397865262234705 P339A-I364A 0.039624809349704 H348A-I359A 0.039251286334828 I361A-Y437A 0.038499074045574 R366A-Y517A 0.0381384867869965 N353A-I361A 0.0380811149895861 R366A-I526A 0.0380337393031023 L470A-S520A 0.0377954191133627 P339A-I360A 0.0365765540153977 F350A-I358A 0.0359885714686241 C423A-M430A 0.0359196245205079 F363A-F433A 0.0358428294312216 I361A-G512A 0.0351814915922182 F509A-I518A 0.0350378157574438 L470A-I478A 0.0348701407621692 G352A-I359A 0.0342236348815979 Q429A-Y437A 0.0336172158412156 Y370A-P425A 0.0335907702234071 S357A-L513A 0.0334464392777398 T362A-G512A 0.0333929857138997 W354A-L440A 0.0327598455219773 S337A-M439A 0.032551722042415 L427A-A435A 0.0325187562152262 M430A-V514A 0.0314729578123778 V365A-L522A 0.0309503576364243 T362A-F433A 0.030879983370145 Y516A-N521A 0.0307089669822422 V519A-T524A 0.0300621153424334 Y370A-S520A 0.030045700016383 P431A-M439A 0.0299437309540314 I361A-L440A 0.029511518190426 W334A-K342A 0.028540694450998 F341A-F433A 0.0285253101390239 W346A-I364A 0.0283563610063799 F356A-L513A 0.0282283687402769 W332A-L440A 0.027877785936131 I347A-N353A 0.0276021035804556 F341A-L513A 0.0275619475158297 Q429A-T524A 0.0271139005245844 T362A-L440A 0.0270757612801487 G352A-I360A 0.0250968840703432 M430A-F509A 0.0250251495050757 L333A-I432A 0.0248439740107447 A435A-Y516A 0.0244960989346019 H348A-G512A 0.0244844530455316 G472A-L513A 0.0242423147985358 M471A-V523A 0.0241557740225655 I336A-K345A 0.0236647733694422 W354A-F363A 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