[Mon Aug 29 17:38:00 2016] >Input file: TMA0A0U1AAJ5M1G.pdb >TM segments: 173-190_ 272-330_ 456-475_ 494-507_ 514-522_ 526-538_ 580-592 MAIDEN score = 19.3583 Below is the ranking list of the residue pairs and their related pseudo-energy (the lower, the better). This includes inter-chain residue pairs. The maximum (least favorable) pairwise energy value has been set to 10. See the MAIDEN software article: Postic,G., Ghouzam,Y. and Gelly,J.C. (2015) Biochimie, 115, 155–161. ----------- ---------------- Calpha pair Empirical energy ----------- ---------------- T279 -L286 10 D284 -P289 10 Q303 -P308 10 T279 -A285 10 M280 -L286 1.49382549499614 M280 -P289 1.40266615079935 I283 -P289 1.30287748765921 L499 -I530 1.11507724985908 F467 -K536 1.10179333011382 M280 -V290 1.07111404462854 F281 -Y296 1.00389540889663 Q469 -L499 0.983345168916379 F281 -V290 0.967167360029861 V468 -F502 0.835088195241701 Q469 -L529 0.806135751658527 L316 -D321 0.792601043532144 L173 -I295 0.752675019191742 Q460 -V507 0.736812492659358 M280 -E291 0.718802112421046 A464 -R504 0.681542896750909 G495 -I530 0.679621147833917 M280 -A292 0.66969535705545 Q498 -I530 0.648957134378456 S494 -I522 0.631451086692368 F467 -G533 0.620278421359169 A304 -M309 0.617845559223895 G495 -I522 0.610153611181492 V468 -K536 0.607613932007815 A465 -I500 0.606465568244057 F467 -A503 0.592989112194601 T279 -H287 0.575161280724665 V468 -L499 0.568823449242149 D314 -F319 0.562184303722956 F281 -P289 0.561896153474086 S174 -I295 0.560881899527911 I506 -M537 0.555949944865969 T300 -F305 0.550891107201622 V468 -E532 0.548332987376526 F305 -T310 0.544316516015568 F502 -L534 0.524580950912407 Y180 -A273 0.499044852749806 A304 -T310 0.487128537540376 I274 -Y296 0.457996295694397 Y301 -Q311 0.446425363774027 P175 -E291 0.435646295626855 T519 -I530 0.433062116425345 T519 -Q531 0.424024093222277 R497 -I530 0.420426553636949 F502 -G533 0.402572099482395 M280 -I295 0.402355494926544 Y296 -Q303 0.398223997598823 A464 -I506 0.396549413212244 M280 -S288 0.391449921611329 I456 -I461 0.387479502703764 Y587 -T592 0.383468011789255 Q463 -K472 0.382599706865599 A470 -I500 0.380982560010757 F473 -Q496 0.376089534119668 T519 -T526 0.360879782311841 I461 -V507 0.359841891233878 C181 -A273 0.356547104948667 Q496 -I530 0.356391148267317 I177 -Y296 0.354032852031687 A520 -E527 0.349422914923483 A470 -Q496 0.346177494250744 V468 -G533 0.343553650392855 V468 -I500 0.340414866842782 R497 -N521 0.338661047391656 V468 -L534 0.333045260006473 M280 -G293 0.328864857163469 K472 -A503 0.325000296819388 D284 -V290 0.319892525544361 S494 -A520 0.316520246049683 V302 -P308 0.315524643140505 V302 -N307 0.313997695645789 N307 -M312 0.309342899394697 V468 -M537 0.309036478837896 S178 -A304 0.308892661442163 Q498 -E532 0.301169869040723 L278 -L286 0.301062315776242 I461 -A503 0.29963162704256 D284 -M294 0.298659820242456 L499 -G533 0.297522756828411 L272 -A277 0.297019326484577 A518 -G533 0.295046169567998 A518 -G528 0.291156074433453 I177 -A273 0.283969343453723 M280 -A285 0.281859080967312 L499 -R504 0.272499576416306 D458 -V507 0.2717913129643 M312 -D321 0.271313338259992 Q463 -M537 0.270851872171383 L276 -G293 0.269943474277927 K462 -F467 0.267125567123575 A273 -G293 0.266178993357792 L173 -G293 0.264529426337532 Q463 -K536 0.263446195895122 E176 -T279 0.259504883062935 R497 -A518 0.258403964585357 Q463 -V468 0.257019649300734 Q498 -E517 0.255639929998914 T279 -D284 0.254382249971442 T300 -T310 0.253985004345191 D516 -M537 0.25208728079095 E176 -H287 0.247915837406957 Q498 -G528 0.245841645276942 Q463 -T505 0.244790053606631 G322 -L330 0.244691512986301 K462 -K472 0.243063580459311 L272 -T279 0.242081438005583 P175 -L182 0.238502799856863 P175 -T300 0.236571396651104 F467 -Q531 0.233454956707818 I461 -E466 0.232747032158453 E532 -R538 0.230021538278325 R504 -M537 0.229782290658958 Q496 -E532 0.229718452396254 E517 -Q531 0.228131004148036 A470 -A503 0.228010556461137 L499 -G528 0.224829310076644 S174 -A277 0.224656313329353 S494 -A518 0.224595046952771 A464 -Q469 0.222905663645165 A273 -Y301 0.222422841841018 P186 -Y301 0.220286746192723 L286 -E291 0.214384598050199 Q463 -G533 0.213266519118391 Q463 -F502 0.213088645024103 P308 -S317 0.212247658191733 G495 -E527 0.211938514138979 G322 -I329 0.211382850258826 Q469 -E527 0.210852705683758 K472 -R497 0.208334734593313 A465 -R497 0.20781451701871 F502 -M537 0.206517360318081 L278 -E291 0.205812286474726 S178 -V299 0.204394033199497 Y180 -A275 0.201201364144108 A275 -G293 0.198303807063253 N521 -G528 0.195237638556546 V468 -R497 0.194590478770719 C181 -L276 0.19124866253782 A503 -E532 0.19123347864976 F306 -M313 0.189294448570111 A465 -L499 0.188822308370421 S178 -M294 0.186888612627265 V302 -M313 0.184816405116843 I283 -A292 0.184053206795921 P175 -L276 0.181619696833934 S501 -I506 0.181017248035545 A325 -L330 0.180977253499172 F281 -L286 0.180248156497042 A464 -D471 0.179082840932919 S174 -A292 0.178616735074097 I177 -A275 0.178257108313862 T505 -A518 0.178039939628565 Q531 -K536 0.174631793810482 T300 -N307 0.173705191972739 A277 -Y296 0.173584870462947 T457 -T505 0.172809515180823 S174 -L276 0.172733369888822 D471 -M537 0.171586683171672 A520 -I530 0.170399846801282 A520 -G528 0.17010077728784 L278 -A285 0.168309212085177 K472 -T526 0.167035158047004 E291 -Y296 0.166817314962666 A520 -G533 0.166385304043406 Q498 -A518 0.166176332298233 L278 -D284 0.16425752623416 A277 -D284 0.163872227832795 E466 -D471 0.163455899062543 T457 -I506 0.162143352855911 D585 -T592 0.16166546735202 I456 -A464 0.160631252653775 I500 -I506 0.160448249478502 L278 -G293 0.159928052604316 C181 -Q303 0.159089227276815 I183 -T300 0.158252389832575 F179 -Y296 0.156538313177206 A465 -E532 0.156359619656726 Q496 -G528 0.156058937666109 Q469 -G528 0.153949258258723 Q469 -S501 0.153862862823043 G495 -G533 0.153810273015339 A470 -T505 0.151864603064092 V514 -A535 0.150441696154649 A275 -I283 0.150050212215236 K462 -T505 0.147588300482364 E517 -R538 0.147519195195801 N307 -D314 0.146741521149598 H287 -A292 0.146202364152685 S178 -Q303 0.145289098870237 L276 -P289 0.145172956138474 A518 -E527 0.145126371508093 Q469 -G495 0.14479195717943 E466 -Q496 0.144572499206999 S174 -S288 0.144329028286638 E176 -I274 0.14365724253422 G282 -M294 0.142551014529897 Q469 -M537 0.142065608026007 S174 -G293 0.141629247402316 S178 -I183 0.14135729398814 V507 -V514 0.140471336018008 S501 -E517 0.140098073738334 A503 -Q531 0.139385998051594 A277 -I283 0.139130715621838 Q498 -M537 0.138467496058414 A470 -L499 0.138375419932617 F281 -M294 0.13599808453193 I500 -E532 0.135396467069315 R504 -R538 0.134659667536909 P308 -L316 0.134591399254687 S178 -A277 0.134427652810194 F298 -F306 0.132644047243925 Q311 -L316 0.13260431733898 I461 -I506 0.132497331010504 T310 -S317 0.130773672406975 Q463 -H475 0.13052062148211 A465 -M537 0.130462225743436 Q303 -M312 0.130322034283954 T310 -I318 0.128098560060055 Y583 -S591 0.128080300063419 L286 -Y296 0.127667255002308 A285 -G293 0.12753609196752 A470 -S494 0.127407612142978 E459 -F467 0.127035187745086 I500 -T526 0.126789065759581 V468 -I530 0.125751169654118 S494 -T519 0.125751032628005 A275 -S288 0.124891682016846 Q496 -L529 0.123495264403687 Q463 -I474 0.122938122640869 G495 -E517 0.12262534805097 I177 -L276 0.122545853154135 D471 -I500 0.121963510435968 Y180 -I295 0.121412840403069 R497 -E532 0.121348019712088 I274 -M280 0.120832734024162 F184 -Q303 0.120055389383911 I283 -Y296 0.119872073063934 A470 -A535 0.119701667385971 Y296 -Y301 0.119678523344668 Q460 -I500 0.1195052160819 A503 -A518 0.119488118868317 S178 -A297 0.118968121696901 G293 -Y301 0.118294085336561 S501 -T519 0.118041930692054 I177 -I295 0.11800584674668 Q463 -S501 0.116823239449711 R497 -Q531 0.116710569094404 E517 -E532 0.115399259608153 S501 -L515 0.115166620323286 S174 -Y180 0.114992534077869 A304 -M313 0.114991824759789 I274 -Y301 0.114673831879929 L515 -A535 0.114007815672454 S501 -A520 0.113943922887113 Q460 -Q469 0.113911397556156 S174 -P289 0.113426076117152 S494 -A503 0.112965256828212 S178 -L272 0.112899163724699 L272 -A285 0.112725844629229 Q460 -A465 0.112311351150786 A275 -A297 0.112298639565712 A277 -S288 0.112229531357302 G282 -P289 0.112156660308787 T300 -F306 0.111178076920872 L185 -L272 0.111055434600879 G282 -V290 0.110657700953448 T457 -A465 0.110394868161166 D284 -E291 0.109365530878422 A273 -V299 0.10934077205513 T505 -K536 0.109060047098212 I318 -A325 0.108270045411231 E459 -I506 0.10807956239362 L276 -L286 0.107910312443264 T505 -L515 0.107338897544082 P175 -A277 0.107057938015815 K472 -I530 0.106692793492607 K462 -S501 0.106331874489592 R497 -G533 0.10608551625226 A503 -R538 0.105968239387255 E176 -L276 0.105690937510329 A273 -G282 0.104915030431366 A503 -A535 0.104450576994604 A470 -G528 0.104149591571131 E459 -D471 0.104024371711496 G495 -A503 0.103455549016037 Q460 -I506 0.102842642612002 Q460 -A470 0.102138519395566 I474 -Q498 0.101715668897205 V514 -A520 0.10162856187014 D471 -K536 0.101000446262581 I323 -R328 0.10083783135256 R497 -E517 0.100818455784501 T519 -G533 0.100790903455057 Y301 -M312 0.100635748859062 L272 -M280 0.099969247389383 D471 -L529 0.0999690735293404 T526 -G533 0.0995698519743253 Q463 -R504 0.0992942779488453 L276 -D284 0.0989192461320005 A518 -E532 0.0987242832590942 T519 -E527 0.0982921386685169 L185 -V302 0.0978790315386022 R497 -R504 0.0974693614149458 F502 -A520 0.0974119798050843 A470 -V507 0.0967981811076433 L276 -H287 0.0957147442607136 L182 -V299 0.0954402099230596 L499 -E527 0.0946137778483729 S178 -L276 0.0942591902829306 M294 -Y301 0.0940882138168084 C181 -F298 0.0934961802531999 S501 -K536 0.0932801992186678 E459 -H475 0.092738514471026 T519 -E532 0.0917466768863218 S501 -A535 0.0915452198205458 V468 -I506 0.0913521063127751 A277 -G293 0.0907740822440202 I474 -L529 0.0901393034211401 E517 -M537 0.0897715571385939 Q496 -L534 0.0897573315029319 E466 -A503 0.0896006174090203 G581 -L589 0.0888225158245888 K472 -G533 0.0888010214030052 V507 -G533 0.0886299288503987 E466 -E532 0.0873552357875833 D516 -R538 0.0873498051967072 T505 -G533 0.0872019551584017 G528 -K536 0.0871058217813991 K462 -F473 0.0867684206999346 L182 -V302 0.0867504770509231 P175 -M280 0.0867160908552052 S501 -G533 0.0866743587137844 L499 -E532 0.0855480946173509 Q469 -R538 0.0848391860500906 A273 -V302 0.0842726334298662 M312 -T320 0.0840137115651398 S174 -T279 0.083721092049529 T505 -R538 0.0835540507722806 A277 -E291 0.0826304950838948 F184 -A277 0.0824141064235873 A465 -L529 0.0815610949529748 I506 -I530 0.0814046237907613 L173 -A292 0.0809712839672638 T505 -I530 0.0804163261981152 A518 -M537 0.0799964030493403 E459 -A464 0.0799571093278866 P175 -Y301 0.0797198495645137 A470 -M537 0.0794116302700973 A470 -L534 0.0782212730274989 E176 -L182 0.0778030878052764 I183 -A277 0.0775857846884666 L173 -A297 0.0773742413701357 K462 -D471 0.0772674433966691 V468 -R538 0.0763606955129781 Q460 -S501 0.0762274862753927 G581 -Q588 0.0759644651412574 I500 -I530 0.0759404099871137 A285 -Y296 0.0759320389613269 Y180 -F298 0.075780006975422 I274 -A292 0.0757288409648593 L499 -Q531 0.075711927741575 I177 -A277 0.0747672284177909 D516 -N521 0.074223197142318 I506 -A518 0.0739753875892011 I183 -L276 0.0732367397838249 H475 -Q496 0.0726589728211695 C181 -Y301 0.0725563536405911 I177 -V302 0.0724892826127812 Y180 -M280 0.0718985624503026 E176 -C181 0.071479856368537 I183 -A304 0.0712704951514542 L276 -A297 0.0710076703384663 E466 -R497 0.070126759634622 F467 -F473 0.0694408768774277 I474 -G495 0.069272461761992 Q463 -I506 0.0692078609855846 R497 -T519 0.0691261965676253 P289 -I295 0.0684567175977151 C181 -A277 0.0684447725272002 I500 -T519 0.0683489490560714 E176 -E291 0.0681908016185955 E466 -L529 0.0676378205587131 E176 -M294 0.0672638255393849 L185 -M309 0.0672414884151 L173 -A277 0.0670346160764344 C181 -V190 0.0669844547015566 R497 -L534 0.0668758190134793 T279 -P289 0.06583373088319 G533 -R538 0.0653863920728393 L499 -V507 0.0649468357977812 A465 -R538 0.0648570083876329 F467 -M537 0.0643033588904789 T279 -I295 0.0642676902616648 I500 -Q531 0.0640546969444231 S317 -G326 0.0640409094871002 Q469 -K536 0.0631628099327128 E466 -I530 0.0624247064465506 N521 -I530 0.0623859949536294 T505 -L534 0.0622462457060671 A285 -E291 0.0621860595652888 D321 -R328 0.0614001163891724 M294 -T300 0.0612010880891531 A503 -L529 0.0611952646597034 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0.0541693022367693 A273 -A285 0.0537544643963308 V299 -N307 0.0533781234615989 E176 -V290 0.0530878239658459 Y180 -L278 0.0529858363071423 K472 -G495 0.0529525813142566 I530 -R538 0.0527313979367023 T320 -I329 0.0527028799108213 I274 -E291 0.0517977963375356 A275 -F298 0.0508114765663348 P175 -C181 0.0506442424988687 F502 -E517 0.0504059168930109 I177 -F298 0.0501888637354857 C181 -V302 0.0501537128799203 L286 -G293 0.0499716711029614 A275 -V290 0.0490021480849805 D516 -Q531 0.0487190426165156 S288 -G293 0.0479412971174853 A297 -A304 0.0478063692715904 S178 -V302 0.0473790773475216 I522 -E527 0.0473422424608128 M280 -F298 0.0467293817670424 I456 -A465 0.0466291140042596 H475 -I500 0.0464153523354135 K462 -F502 0.0463216902555548 M313 -I323 0.0459271623680273 I187 -L272 0.0455637458872027 D471 -S501 0.0454942156637521 A273 -Y296 0.0454565483913889 S501 -D516 0.0451257577871964 A465 -Q496 0.0448566743803969 I530 -K536 0.0448164110412455 F184 -T300 0.0445522671945753 S501 -Q531 0.0438078229139736 S501 -E532 0.0437221662218148 L582 -Q590 0.0431495399193125 S494 -G528 0.0429556092413506 Q460 -D471 0.042887466947185 V299 -M309 0.0426248069642146 M280 -M294 0.0424539594985081 Q460 -V468 0.0417327117682436 E517 -G528 0.0414888351637268 T310 -F319 0.0413796792930894 F184 -L276 0.0410604576457088 V302 -M312 0.0409998164319672 E176 -L272 0.0409840104976977 T519 -K536 0.0408945223406527 T505 -Q531 0.0405709687734236 M294 -V302 0.0402822055109109 T300 -Q311 0.0394521873848243 Q311 -T320 0.0391905716973678 R504 -V514 0.0390684791150093 S317 -A325 0.0390089114584171 E466 -V507 0.0388482770609477 G581 -Y587 0.0384497514572741 T519 -M537 0.0383159171271181 T526 -L534 0.0377594601051765 L173 -P289 0.0376841934090155 L272 -A297 0.0374522351862785 T457 -A503 0.037437600400904 A465 -I530 0.0369850432042358 D471 -G533 0.0368728747512699 A277 -H287 0.0366479325707878 S494 -L529 0.0362884620091788 A503 -L515 0.0361626635720644 E176 -M280 0.0359779935199571 L276 -A292 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