[Mon Aug 29 17:01:28 2016] >Input file: TMA5PCZ5M5G.pdb >TM segments: 161-181_ 258-315_ 450-475_ 478-491_ 500-508_ 511-524 MAIDEN score = -23.6033 Below is the ranking list of the residue pairs and their related pseudo-energy (the lower, the better). This includes inter-chain residue pairs. The maximum (least favorable) pairwise energy value has been set to 10. See the MAIDEN software article: Postic,G., Ghouzam,Y. and Gelly,J.C. (2015) Biochimie, 115, 155–161. ----------- ---------------- Calpha pair Empirical energy ----------- ---------------- V271 -L276 1.27308424692744 A450 -R490 1.09076203331346 V453 -D522 0.979396814983808 V268 -D273 0.961479211508584 L295 -Q300 0.896409749044629 P168 -P173 0.85553517197892 Q484 -L516 0.849698860876646 S505 -I517 0.760244752681868 I488 -E523 0.734796908548736 S451 -I486 0.686619004433956 V167 -G262 0.674321702067677 A261 -V266 0.649234445287207 S461 -G466 0.641919611500285 V263 -A283 0.635028568735357 G455 -S485 0.634700738067933 F459 -G466 0.611749711579765 M508 -E513 0.606235755447264 V164 -G280 0.584066926685553 N465 -K470 0.578147103370719 V172 -R290 0.550561022478193 I517 -D522 0.548614078160975 P168 -A283 0.533372420634592 S505 -L516 0.497927005480566 S464 -L469 0.483153157585871 M171 -S259 0.470985723894042 S454 -L516 0.469201349057724 I176 -R290 0.462218558422467 Y467 -Q482 0.460723414900106 V453 -E523 0.454834644361098 Q484 -P504 0.44750137904327 S451 -V460 0.435813865683045 I488 -L520 0.417463584164485 V453 -A489 0.41559927718307 V167 -V263 0.412474383435544 V165 -A283 0.410560140430942 I488 -M501 0.404828914975406 T456 -Q482 0.404323531566674 S454 -I488 0.402673590468847 V172 -L287 0.398748066656803 A293 -I298 0.394609624013381 D515 -L520 0.392173388807418 V164 -G267 0.388215391916946 P504 -E523 0.384642517785923 D457 -Y467 0.361369869227294 L516 -K521 0.35631870851824 P504 -N518 0.346518665513145 G480 -M508 0.341715031467836 G289 -P294 0.336341435433534 R519 -L524 0.326715103836181 V164 -Y260 0.326517281421566 R452 -D522 0.323286836484707 I292 -Q297 0.314522476249952 G455 -A487 0.309872059131124 Y260 -I265 0.307119232075152 V268 -L276 0.306661742277417 A491 -K521 0.305559713274982 G279 -C284 0.303581772533181 G481 -M508 0.301614957224798 G279 -S285 0.298730472770066 I258 -C284 0.297276639625355 V266 -C284 0.295947481725625 Q484 -M501 0.295767699995676 V460 -G466 0.29172897900609 V164 -A283 0.286451566398839 S485 -K521 0.284409219901234 G466 -L471 0.282051994376591 R452 -Y467 0.27883563433825 R452 -L458 0.278286597777934 E513 -R519 0.273884102784768 V271 -T277 0.267782343940471 Y467 -V472 0.266627115736244 S485 -L520 0.26196111470587 A487 -R519 0.257608650193161 G481 -S506 0.254783260603408 G161 -A169 0.25391048806951 P294 -S299 0.251146116745471 S454 -L520 0.25056044642176 D468 -D473 0.25054806629405 Q482 -E513 0.247514580794564 G455 -D522 0.2463915428264 G480 -Q511 0.245158076199361 G455 -Q511 0.245119979169873 M171 -R290 0.243867998760839 G455 -R519 0.241199837851914 I298 -R304 0.240724318286301 G267 -D273 0.240583795084566 G475 -R483 0.240047033055315 A450 -A489 0.238144625407571 Q511 -L516 0.237947444529462 A489 -K521 0.236486833299563 A169 -G262 0.236435454450296 V266 -V271 0.235981672676685 Q484 -E503 0.23444676614423 F459 -G481 0.231589323967162 G481 -N518 0.230705436380308 K470 -R483 0.230131890808098 S451 -S485 0.229266527209646 R490 -M501 0.227686497533352 S461 -S485 0.22664517544634 V164 -I286 0.226628603229186 R452 -N518 0.225524835105744 A261 -F269 0.223174334971994 A491 -R519 0.222264855660879 A169 -L174 0.221380054007879 M270 -K275 0.220911768679342 Q484 -A489 0.220430223623434 S451 -T456 0.219136855444415 P173 -L287 0.218677299835733 V271 -G279 0.218153072048859 A166 -S259 0.218111130408974 C284 -I292 0.214082944419903 V164 -V266 0.213781568976322 Q482 -S505 0.213181957496778 M501 -R519 0.212072696966233 S485 -L516 0.211995298717703 S479 -S506 0.211902957211718 M171 -V264 0.2115365436358 V167 -M270 0.210455865728326 V164 -V271 0.207190203302561 G455 -A514 0.204945200791085 S451 -G466 0.204458178565083 R309 -H314 0.203664365314809 I488 -T512 0.200109255852307 G455 -E523 0.199116328102054 R483 -A507 0.198943237244438 A272 -T277 0.198499641980019 G262 -A283 0.19549270227111 P294 -G303 0.194973478382614 G481 -L516 0.193762066541775 I298 -G303 0.19283704407277 A450 -I488 0.192391067419162 S485 -N518 0.190416634779707 A307 -H314 0.189986887754115 V460 -S485 0.186580913911773 S506 -N518 0.185314990782703 P168 -V263 0.185123824658725 S259 -S285 0.183283955163913 R483 -M508 0.183090632737296 D502 -A507 0.181891515963629 M171 -S285 0.181774298164652 S454 -S505 0.179358824525253 R490 -D502 0.179256327720743 V268 -G280 0.179159904003561 I258 -V266 0.178717285084749 R483 -D502 0.17867395601357 G161 -L276 0.177983969122311 S259 -G267 0.177392186160206 D502 -R519 0.176318321684363 V165 -S285 0.175437583872443 S451 -L520 0.174495648374471 R490 -D522 0.173896195681652 G455 -D515 0.171841526516056 T306 -H314 0.169064767726561 V264 -D273 0.168461215122362 G267 -A272 0.167501201482093 S451 -R483 0.167244175566355 R483 -Q511 0.1661746554093 V172 -A293 0.163450724719418 G162 -A170 0.163330613677578 A169 -I176 0.163060109677249 S479 -A487 0.16290048539719 T456 -I486 0.16257575473696 R483 -S505 0.162457965234224 R452 -R483 0.162381728190688 G475 -Q484 0.162316571107054 L478 -M508 0.1623155515915 V263 -I286 0.162176484461533 V167 -V268 0.161831043996511 A170 -I258 0.161106683771338 S485 -R519 0.160084621049235 A166 -G262 0.160021421180405 Q484 -E523 0.157539704829707 R290 -S299 0.155661634566922 M171 -I258 0.154218682495934 I486 -M501 0.153268613997737 L471 -G480 0.152799698865115 V453 -I517 0.152690138147234 G280 -G289 0.151049640790796 R452 -A491 0.150052289383314 V165 -G262 0.150026599480887 S461 -Y467 0.148804244274087 N465 -D473 0.148763005092371 S285 -A293 0.148234637871633 V175 -R290 0.147621231452725 V172 -G289 0.147013095547154 W163 -T277 0.146507134173832 R462 -Q482 0.146468637789933 R452 -Q482 0.1463741480106 Y260 -L281 0.146200235666944 V453 -D515 0.145796096423558 V165 -I282 0.145555046735821 V453 -S485 0.145229485498506 S454 -M501 0.144709866895342 W163 -G279 0.141868213496576 L180 -P294 0.141822423851712 D457 -N518 0.140404399394051 A169 -I258 0.14016298840635 Q300 -I305 0.139591821208434 S299 -T306 0.138456009555609 T456 -A491 0.138103420641829 V172 -S285 0.137153756885996 W163 -L281 0.13711731878861 M171 -A283 0.136871261017826 V500 -S505 0.136343893876953 S506 -T512 0.135303603311643 A450 -D457 0.134469634728545 P168 -G267 0.134053645191219 G480 -A507 0.134039311096247 L458 -S464 0.133576445678021 A169 -A288 0.13350881523488 P504 -R519 0.132884982401855 G455 -R462 0.132205847542822 Y467 -A489 0.131539395955009 A166 -I282 0.130160278079014 S485 -S506 0.129724769933367 G262 -M270 0.128728350112141 A487 -D502 0.127522678112858 V164 -K275 0.126777722800997 I486 -T512 0.126597099923006 A489 -D522 0.126595793963844 S485 -E503 0.125986863531947 T456 -I517 0.125917624342199 A450 -Q484 0.125793820362057 P168 -G280 0.125782841880157 Q511 -N518 0.125676022936878 A487 -I517 0.125550074122749 G481 -I517 0.125434028739596 W163 -G267 0.123203654445178 A169 -A291 0.123042694555985 V500 -L524 0.122398603464047 V178 -S259 0.12140458327941 I265 -M270 0.120987774769457 V165 -Y260 0.120975707636771 I265 -G280 0.120790865285353 W163 -A170 0.120632718493389 A170 -L177 0.119621044907366 G480 -E503 0.119377661362036 S454 -Q511 0.11917146351993 S454 -E523 0.118231489116937 G455 -L516 0.117813567148636 Q484 -A514 0.117714010834162 S485 -A514 0.117711251813572 E513 -E523 0.117596131856328 V167 -S259 0.117152006741056 Q482 -I517 0.116943775446748 A507 -L520 0.116460499365306 T456 -R490 0.116188389181685 P173 -A291 0.115882614577358 L458 -L516 0.115845008718469 A507 -E513 0.115580853417106 I258 -L287 0.115163465613602 S461 -L469 0.114927047832976 R483 -A491 0.114866013897765 L174 -L287 0.114472833612803 L471 -S479 0.113895452625647 V266 -G279 0.113633438113873 V175 -G262 0.113572207673972 T456 -G480 0.113553484593189 G161 -V263 0.113477714302392 R483 -I488 0.113080290844905 V500 -D522 0.112964428129215 V263 -A272 0.112620858816578 V175 -L295 0.112554654647275 L458 -L469 0.111932780738293 G162 -A169 0.111672721320408 A507 -A514 0.111643284613907 V266 -T277 0.111600123116668 L478 -R483 0.110512888003239 I258 -G267 0.110374154992421 S461 -D468 0.110177088098894 A489 -E523 0.110050464863286 G466 -G475 0.109964111684195 S259 -A291 0.10969380539556 S454 -G481 0.108960843943658 G475 -A487 0.108912681237646 G455 -Y467 0.108886617474973 V164 -S259 0.108877948072974 S506 -L516 0.108251973554549 V165 -A261 0.108243213665363 A169 -G289 0.108190944297483 V164 -A261 0.10809110858276 P504 -D515 0.108005889923326 A170 -A283 0.107870665141148 A291 -Q300 0.107825607886411 A291 -A296 0.107582872094405 Q300 -A307 0.10754684593076 A170 -G267 0.107443703447294 L471 -L478 0.106957171764888 P168 -S259 0.106461562664232 S259 -A288 0.106220525752875 A507 -L516 0.106053913978803 A450 -D522 0.105566622612928 V172 -L295 0.105296243860115 G481 -L520 0.105228495641237 V453 -T512 0.105212806892854 I265 -A283 0.104396702148795 Y260 -I286 0.104177576788256 L458 -Y467 0.103961179621524 A489 -N518 0.103501447114152 G262 -G280 0.103285806631162 L174 -L295 0.102836626740958 P173 -L295 0.102582713985495 R474 -Q482 0.102385700036223 Q482 -M508 0.102153628882948 V172 -S259 0.10173347698225 G179 -A291 0.101424024396992 I488 -E503 0.101231883377785 V172 -A296 0.100734528942952 R452 -A487 0.100311313090068 V172 -G262 0.100202840115806 A166 -S285 0.0984981417500526 A170 -V264 0.0981157502446002 I463 -L469 0.0974259649404581 I486 -E523 0.0973046706882004 A489 -V500 0.0972541552422994 S505 -K521 0.0971290865058847 I265 -T277 0.0971043273530832 A170 -V266 0.0971032785535741 P173 -Y260 0.0970732992537662 S505 -R519 0.0966783670174063 G161 -I286 0.0963989778816678 I488 -N518 0.0961209291253429 L458 -L478 0.0957731174150773 A450 -Y467 0.0957159642398362 L516 -E523 0.0952349276838895 A283 -A291 0.0950746903983104 A491 -E523 0.0942678328659214 I265 -L281 0.0936564932908865 S479 -I486 0.0936432065657011 G267 -K275 0.0928689779327498 T456 -G466 0.0927176058482915 R483 -R490 0.0925212437932225 V264 -G279 0.092511326654146 A514 -D522 0.0919882839977846 A169 -S285 0.0914143777155956 A261 -L281 0.0910829341411681 V263 -L278 0.0910501481001331 L287 -Q297 0.091017648408251 L458 -Q511 0.0909389050308673 G481 -E503 0.0908395034206277 V302 -A311 0.090302753850545 D502 -K521 0.0902401993509535 S506 -I517 0.0898113148978816 T512 -K521 0.0892308641878472 V266 -N274 0.0885416978998855 R490 -P504 0.0884224058863734 A170 -Y260 0.0883929467895923 L174 -I286 0.088368273974656 G162 -G262 0.0882953718019617 S259 -C284 0.0879666884134349 R290 -Q300 0.0879336908834363 I298 -T306 0.0875079516061212 A169 -I282 0.0870619361174185 A450 -V460 0.0869732298331969 R452 -Q484 0.0868524789289635 T456 -L478 0.0868135053008956 K275 -G280 0.0865961509096882 A169 -V266 0.0862584320930715 V167 -Y260 0.0862566288656084 L458 -R483 0.0860200738883115 L177 -R290 0.0859875615910982 T456 -A489 0.0858109753961251 A491 -P504 0.0855542608689914 V453 -L458 0.085242376990597 L458 -I488 0.0847406877110907 A169 -Y260 0.0845073971872861 G303 -R309 0.0844827090014251 S485 -E523 0.0844079542679315 M171 -V266 0.0839899762438607 G455 -K521 0.0839854145496913 L458 -R519 0.0839389373473111 A489 -I517 0.0835456273620494 D457 -I463 0.0834969141018624 V263 -G279 0.083473130683033 V266 -A283 0.0833313822898325 L478 -S485 0.083192010329145 G279 -I286 0.0828804933283696 Q482 -S506 0.0823012528246148 G161 -G267 0.0815158391273734 G466 -V472 0.0814088955639569 V164 -L287 0.0809154682100173 G161 -T277 0.0808207415716153 A288 -A293 0.0796057912251316 I286 -P294 0.0795390973498737 V266 -L278 0.0794394252425903 V460 -A487 0.0794356029377639 Q482 -A514 0.0793577223197923 V460 -L471 0.0793186079111896 A261 -C284 0.0789246553696814 R474 -S479 0.0785624037861636 V178 -L295 0.0783905074549176 Q484 -Q511 0.0781847357666847 I176 -G289 0.0780974207831031 M171 -A291 0.0779974947293607 S451 -A491 0.077953515008975 R483 -T512 0.0775254097975555 V165 -L281 0.0773265763066959 S485 -A507 0.0772100288056403 C284 -A291 0.0766074455713963 V271 -L281 0.0765168338056501 I488 -A507 0.0762918745512983 L177 -L295 0.0762812853279851 V172 -Y260 0.0762499398838559 A307 -V315 0.0762466130669512 L469 -R483 0.0759995882565304 G267 -L276 0.0743916212541 S505 -E513 0.0743245001832653 M171 -I286 0.0741379740604255 G455 -G466 0.0741115972792322 S259 -A283 0.0738858779548544 A450 -S461 0.0738619589476386 Q482 -A507 0.0730163147230873 V175 -I292 0.0728455870750468 G162 -V271 0.0726829317246054 G475 -G481 0.0726230264627629 V266 -K275 0.0726037489024307 G161 -P168 0.0725762060564379 I176 -I292 0.0723117546382905 V460 -R483 0.071832718397671 S451 -A489 0.070796841139255 W163 -V268 0.0707722398448607 L458 -Q484 0.0706848357787471 S454 -I486 0.0705092146573121 L180 -I298 0.0699458798730248 V164 -S285 0.069934357964196 V164 -V172 0.0699134497324039 T456 -A514 0.0691882687116419 G455 -R490 0.0689821784547986 A166 -G267 0.0688849505380107 S451 -I488 0.0681877270203834 T456 -L520 0.0678527848020002 R474 -Q484 0.0678347195533755 N465 -V472 0.0678282195656708 V472 -R483 0.0672332901017407 V164 -L278 0.0669634839880473 V165 -S259 0.0666250796488557 G303 -T310 0.066554516715454 D515 -E523 0.0664869678959348 I265 -A272 0.066474676272434 A489 -M501 0.0663579820039173 A296 -I305 0.0663462244915962 V460 -A489 0.0659480016967064 G267 -C284 0.0650980177489204 V264 -I282 0.06495323765715 R483 -A514 0.0647804206593778 A166 -R290 0.0646725024930954 L276 -A283 0.0644143615027293 G267 -N274 0.0642886372454425 S454 -L524 0.0642506570471584 I486 -M508 0.0638690940513413 V264 -L287 0.0637602115493037 V453 -Q482 0.0633214682976679 F459 -K470 0.0624176918108237 M270 -G279 0.0623966541335426 R304 -R309 0.0621687407108738 I298 -A307 0.0617442021249683 L469 -L478 0.0615262597423687 G455 -A491 0.0610107308916996 R474 -R483 0.0609215507046539 L458 -N465 0.0604986625728445 G161 -N274 0.0602588851917766 P173 -P294 0.0602104391208922 S485 -D522 0.0601997208409075 M171 -L180 0.0601710779928588 G161 -V266 0.0594800046813706 V164 -C284 0.0594622549085144 V164 -A272 0.0590577414596982 G161 -G280 0.0590053595807802 A450 -L524 0.0588978279680483 A487 -S506 0.0586776035092456 A450 -G466 0.0583810492344023 L478 -A487 0.058181897689725 L516 -L524 0.0580868177073439 V453 -Q484 0.0571236253047429 A169 -G267 0.057054024164404 V263 -I282 0.0564099698413081 V472 -Q482 0.0563512098306811 A450 -L516 0.0563349913499731 P168 -R290 0.0562646106339171 G455 -E513 0.0561744262280075 V164 -T277 0.0557351752467969 V175 -A291 0.055648532450181 G280 -L287 0.0555731447561986 V172 -I292 0.0554610462705813 L174 -A291 0.0554237318412256 I282 -R290 0.0550059891819092 A170 -C284 0.0549432576856277 Q484 -V500 0.0548437619777253 S454 -R483 0.054719693905156 I176 -A293 0.054670927652599 L177 -A291 0.0544324922369324 L471 -A487 0.054053628387061 G267 -I282 0.0537938545629473 F459 -Q484 0.0532852064737233 R490 -V500 0.0528234729184665 Q297 -V302 0.0521474311446992 S506 -Q511 0.0521315117222239 V175 -L180 0.0520517630840303 E503 -R519 0.0520449950732784 D457 -S464 0.0520362384063456 I286 -A296 0.0519967902791851 M171 -I265 0.0519065903474658 D473 -S479 0.0518021140474863 V460 -G475 0.051770465421717 M508 -L520 0.0517373841794893 A170 -G179 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