[Mon Aug 29 17:38:17 2016] >Input file: TME5SY86M15G.pdb >TM segments: 171-193_ 211-227_ 269-284_ 316-329_ 349-363 MAIDEN score = -1.9414 Below is the ranking list of the residue pairs and their related pseudo-energy (the lower, the better). This includes inter-chain residue pairs. The maximum (least favorable) pairwise energy value has been set to 10. See the MAIDEN software article: Postic,G., Ghouzam,Y. and Gelly,J.C. (2015) Biochimie, 115, 155–161. ----------- ---------------- Calpha pair Empirical energy ----------- ---------------- C323 -I356 10 H181 -I223 7.45215987860297 H192 -R278 1.23050276914627 P174 -L227 1.13736683233733 A269 -R274 1.0738292350226 H181 -N270 1.03779046984859 W324 -I356 1.03478515816533 E191 -L282 0.969227122429925 T177 -C226 0.937143386393378 W180 -I223 0.886910191181293 P174 -P224 0.857098727068953 W324 -L352 0.789668286383818 H192 -P281 0.788447564054839 Y327 -I356 0.763333340665624 Y327 -I349 0.731985166484137 S179 -I223 0.716116419635282 D176 -V357 0.700233682167953 P326 -L352 0.698011527976867 V184 -R274 0.664312010576914 Q182 -W222 0.654864958610631 S185 -R274 0.643046166533324 W187 -L316 0.606780409460709 A178 -P224 0.605486426119842 K175 -L227 0.575959445035369 V184 -Y320 0.570764334075718 Y320 -N359 0.557646801257524 W324 -L355 0.547336546869136 Y320 -L325 0.540546111688228 I223 -N270 0.535231127208808 K175 -W180 0.526822957472738 W180 -N359 0.506524285733185 S185 -I223 0.501746790850047 V186 -Y215 0.483113636136634 W187 -I317 0.473028463105777 V184 -S271 0.471245271579612 Q173 -L227 0.468538258822848 F188 -L275 0.462861840082416 Q182 -K190 0.448946557076012 S185 -W222 0.435836631899033 C323 -L355 0.429142750394571 A189 -T219 0.403072152070375 S179 -S360 0.396012038227715 P326 -N353 0.391486360320741 V184 -N270 0.390862335668644 H192 -S283 0.385980109525767 Y327 -L355 0.385045844658124 W324 -N353 0.382813606999704 Q182 -H216 0.375605183061129 H181 -W222 0.373359648202521 W222 -N270 0.367387437972601 Q182 -P224 0.365398743777583 H181 -S360 0.362152764956746 C183 -C226 0.360877310753978 H181 -V186 0.352423899423206 W324 -N359 0.348042275305569 A189 -K273 0.347365790994339 Q173 -Y327 0.346328649623224 H181 -H216 0.345661523158374 N270 -R278 0.34500618895375 T177 -I223 0.34345262348587 P326 -N359 0.342904352048435 C183 -K273 0.342364577834708 W187 -P281 0.341440320783197 K175 -A225 0.340222889765899 H181 -T219 0.331725180148129 H192 -H216 0.33088088568027 F188 -S277 0.325299398837132 A178 -I223 0.324264032675645 C323 -A358 0.315661809421517 T177 -T219 0.315036409837 H181 -C323 0.314973958321795 H181 -S272 0.309317749275024 C183 -C323 0.305122316105078 S185 -L218 0.303681530376767 T319 -I362 0.300966267664867 S185 -A225 0.298571912396168 Y327 -L352 0.29517060064442 A178 -C226 0.287956344832428 R274 -L279 0.284215749706622 K175 -P224 0.283036085481734 K175 -A358 0.266268026081761 K190 -P281 0.265969409634879 D176 -H181 0.261593555785556 Q173 -A178 0.25918995685634 H181 -L218 0.258942418429155 S179 -L227 0.249943531968675 Y354 -S360 0.249128120464218 S271 -Y320 0.247438050328998 S185 -Y320 0.245938244414798 V184 -W222 0.241173123409316 C183 -N359 0.240440114762951 W222 -K273 0.239824782121651 T219 -P224 0.238488580120544 T177 -P224 0.238340500094426 V186 -H216 0.23022430121395 I322 -V329 0.227825721036054 S185 -S360 0.226905749452074 F351 -A358 0.22416295802919 Q173 -C226 0.222186287551529 D176 -L227 0.217555106709669 W180 -T319 0.216795075798816 V186 -I214 0.215232787322289 V186 -E191 0.214635517973547 K175 -N359 0.21440565294473 T177 -W222 0.214276860226913 A269 -S277 0.213142808612879 S272 -P281 0.21272243844116 W180 -W324 0.212681590767102 S272 -P326 0.212183917579874 W324 -V357 0.208788381389147 S185 -Q193 0.208662705534866 H181 -K273 0.206072374594015 V186 -F221 0.20451481219243 A225 -S271 0.203931242234349 H192 -P284 0.203354706827888 F188 -R274 0.202263081560905 V186 -V220 0.199865300131838 D176 -N353 0.19739117580208 H181 -Y327 0.196957056186328 H181 -V321 0.195302387554056 C183 -R278 0.194506702700776 H192 -T219 0.194106008178478 A189 -Y215 0.194081858318093 H181 -V357 0.192995778358133 Y215 -W222 0.191869687603238 Q173 -Q182 0.191699534389131 S272 -V321 0.189203050690365 P174 -Q182 0.188761731106567 K190 -Y215 0.185903186151532 E191 -H216 0.185895727486138 S179 -N328 0.185314990782703 K190 -S213 0.184223473722266 L276 -P284 0.183382931247339 V217 -W222 0.18303496244235 E191 -Y212 0.182399490610515 W187 -K273 0.182014188699355 S179 -A225 0.181667757606393 K190 -L275 0.181647822407871 T219 -A269 0.180736855285606 S272 -Y320 0.176818365661621 C183 -I318 0.176366513643387 K175 -W222 0.175904529653866 N328 -Y354 0.174632345441328 Q182 -N270 0.172528841602507 Q173 -P224 0.170106578771263 W187 -Y215 0.16942106818768 Q193 -S277 0.169396725509907 T177 -W324 0.167319087016874 Y212 -V220 0.167173724359414 Q193 -S213 0.164445874865385 L227 -S271 0.163367427292316 W187 -W324 0.162561924570124 E191 -R274 0.160013715775953 P174 -H181 0.159694194657442 S185 -L227 0.159244404515972 W180 -L316 0.155130596343295 D176 -N363 0.154836011537015 V184 -A225 0.154758227735254 V184 -H192 0.153830292958396 N270 -L275 0.153232691121795 T177 -A358 0.152969961157564 S179 -W324 0.152628373848849 Y320 -Y354 0.152163208199343 Q193 -P284 0.150605782962699 V186 -S277 0.14806895794202 E191 -R278 0.147920897030478 W187 -T319 0.147444773826655 H181 -L227 0.144951364597757 C183 -L218 0.144437067133651 N328 -N359 0.143945668502021 W187 -N270 0.142882517324857 S185 -S213 0.142826397264682 V321 -V361 0.142661941473319 W324 -S360 0.14261733975628 P326 -I356 0.142444492277622 S179 -V357 0.141800566952267 S271 -C323 0.141343342628605 Y320 -L352 0.140902546360989 Y172 -S360 0.140271906507921 Y354 -I362 0.139631103568212 C226 -S272 0.13914092948745 K190 -L279 0.138642122758903 C183 -Y320 0.138461597703808 H181 -V217 0.13768705260503 R274 -I280 0.136505003973749 E191 -P284 0.136268835042793 T219 -K273 0.135122056745167 V321 -V357 0.134987599908683 F221 -C226 0.134501476883954 C183 -L325 0.134191481704969 K190 -I214 0.133352144194029 C183 -H192 0.129631036750718 W180 -L227 0.128534885941724 W187 -S271 0.128182411194627 C226 -R274 0.12808322704611 L279 -L316 0.12797050332942 C323 -V357 0.126858739654805 E191 -S277 0.126061126581795 I280 -I317 0.125147601258359 S272 -V329 0.124101387347727 V186 -P224 0.123772209276431 Q182 -S213 0.121797059853305 Q182 -R278 0.12173918011236 C183 -F188 0.117560008619984 V186 -S213 0.116279640508605 V171 -D176 0.115505163104766 S185 -C226 0.113538822031907 S272 -N328 0.113368785288642 S272 -L325 0.113047259550945 L282 -L316 0.11169162741307 T350 -A358 0.111546507409221 C183 -S271 0.110936849029333 Q193 -R278 0.110626181455638 L316 -N363 0.110506926184176 W324 -Y354 0.110149105615891 T177 -S360 0.109443803212607 H192 -Y212 0.10860497896572 T177 -V220 0.108395612627015 V186 -A269 0.108348602629508 N270 -W324 0.108308888875168 N270 -L325 0.108290574780047 Q182 -N359 0.107693345982465 C183 -V217 0.107392499768176 C183 -I356 0.10715835811639 I322 -Y354 0.107094893915384 W180 -R274 0.10685265796065 W187 -L275 0.106108533771649 S185 -L275 0.10603578916013 D176 -Y327 0.105071149034678 Y172 -L227 0.104925581884079 A178 -V361 0.104749365296585 I322 -I362 0.104282664006759 A178 -L227 0.104103189214817 S185 -A211 0.103970946558354 T177 -V361 0.103745715215275 V329 -L355 0.10333572512902 S185 -V321 0.103243949719312 L279 -V321 0.103102629878967 K175 -I356 0.10252571949867 V171 -P224 0.102286024188706 V184 -L279 0.102272801985535 H181 -Y320 0.102165331540272 Y320 -V329 0.101244298005094 H181 -P224 0.10123097516568 S271 -V329 0.100966487082599 C183 -S272 0.100736390533451 E191 -I318 0.100512594142727 L218 -N270 0.0999351439431575 S185 -Y212 0.0998039981799694 Q182 -C226 0.09893192053785 P326 -A358 0.0975103258296883 L316 -L325 0.096700636647105 Y327 -Y354 0.0962614096299637 W187 -L279 0.0960975739008569 P174 -V220 0.0959960592580136 C183 -S277 0.0958017028288582 V184 -Y215 0.0957982644458415 Y172 -I356 0.0956860001632869 H181 -C226 0.095442335322482 A189 -L276 0.0953171791613743 I318 -I362 0.0951797164537656 E191 -K273 0.0949151340343257 V184 -I318 0.0948171078412443 V184 -S360 0.0934477992100389 H192 -A211 0.0933772576204692 L325 -I362 0.0929574187008648 D176 -W324 0.092177008616944 Q173 -N353 0.0921224227800165 W180 -L352 0.0918726821418092 T177 -F221 0.0908432547006452 R274 -V321 0.0903817149557824 A178 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0.0752274322980728 L276 -V321 0.0752150301462893 V186 -K273 0.075007190498364 S271 -R278 0.0748718694734913 Q182 -Y320 0.074796184733147 I223 -L275 0.0744860758246757 P281 -L316 0.0742723546540562 T319 -N328 0.074144548152911 Q182 -I317 0.0730332853315172 R274 -P281 0.0729522294307352 V184 -L227 0.0728795304589758 R278 -I317 0.0726379799569159 W187 -I223 0.0726098746538391 P174 -Y354 0.0722032488661051 R278 -L316 0.0721557178849524 H192 -L276 0.0717748090071533 L316 -A358 0.0711699605517846 F188 -L276 0.0707881377573907 S272 -W324 0.0707856798841411 V329 -N353 0.0707011255928274 I356 -N363 0.0700937992292368 Y320 -V361 0.0700536987964391 I349 -V357 0.0696938486418626 V184 -N328 0.0696722282324314 Q182 -V357 0.0689589220098433 Q193 -R274 0.0686940712244538 Q173 -I223 0.0685922634006401 W180 -P224 0.0682875275407211 E191 -Y215 0.0679097548491363 I318 -V361 0.0677503887578392 S185 -L276 0.0675101176735422 S272 -I317 0.0665563304402315 Q173 -L352 0.0661042915708929 I317 -I362 0.0658767572142001 S179 -H216 0.0657344278817692 Y172 -P224 0.0651242737945519 W324 -T350 0.065075843220634 R278 -V321 0.0644864520267943 A178 -R274 0.0644741248751721 D176 -I356 0.0641259351021799 V186 -Y320 0.0639056403678788 Y320 -N328 0.0633211993455918 H181 -I362 0.0628295129528972 I322 -N353 0.0619853527847796 Y215 -P224 0.061729572707937 S179 -W222 0.0617241333673997 L275 -L316 0.0614574784802975 A178 -L218 0.0614413514356675 W187 -H192 0.0614049843507677 Q173 -S360 0.0610126508285229 V184 -N363 0.0608251715335899 L355 -V361 0.0604632136948693 F188 -W222 0.0599991826666741 S185 -S277 0.0597449927751439 V186 -S271 0.0596692238805536 S179 -Y320 0.059588829176791 D176 -V220 0.0595727798815338 V217 -C226 0.0591903348896237 Q193 -I280 0.0583119959049152 V184 -H216 0.0580720169496542 L275 -I322 0.0580649417314705 V184 -A269 0.0576249418651962 T319 -V361 0.0572847044109119 T319 -S360 0.057205245484973 D176 -S271 0.0562869055839981 S179 -N353 0.056128383809289 W187 -S272 0.0561254944290712 H181 -R274 0.0559675790352463 F188 -I214 0.0559399909265514 V220 -A225 0.055709313836104 D176 -N270 0.0551937731772352 P174 -A225 0.0541837556671432 S179 -N270 0.0540062072949006 W187 -V217 0.0516241698030395 F188 -I318 0.0512260716047073 K175 -V220 0.0511754337669685 I223 -S271 0.0506332923431809 Q193 -S283 0.05062860464527 C183 -T219 0.0498461697693102 Q182 -V361 0.0491144641578343 A189 -V220 0.0491144555712157 L316 -S360 0.0489218204449609 F188 -N270 0.0487507639626943 H192 -L275 0.047753285366344 A189 -L275 0.0476795008274675 C183 -F221 0.0468146195375447 A189 -W222 0.0466285845755028 H181 -L275 0.0460738412752885 H181 -I322 0.0460539005509881 S271 -Y327 0.0458768102748528 S185 -T319 0.0458708904758414 W180 -S360 0.04457675868436 H181 -A189 0.0445363221134003 S185 -L316 0.0439430581637119 K190 -L218 0.0438383233813777 P174 -W180 0.043527336040876 S179 -S271 0.0435134005027669 S271 -L279 0.0434641960837905 N328 -L352 0.0432509534952823 W180 -I362 0.0422236134286003 N328 -V357 0.0416589744254585 K273 -Y320 0.0411140316535805 W324 -V329 0.0410180863417882 T177 -A269 0.0403970311974671 K190 -T319 0.0403685223712628 K175 -T219 0.0399884344932779 W222 -R274 0.039151145040778 S185 -T219 0.0391450217512785 N353 -N359 0.0390540429341433 V184 -C226 0.0390319525996468 L275 -T319 0.0386406965765267 F188 -V321 0.038531700398461 H181 -L276 0.0384708532662219 Y320 -L355 0.0383360104857013 T177 -N328 0.0370923171193418 I322 -V361 0.036653596477032 S185 -S272 0.0366410235779209 W187 -R278 0.0364803923290249 N270 -V321 0.036287381972925 S185 -V220 0.035902796955984 Q182 -R274 0.0358143736916055 Q193 -T219 0.0352732152582087 I318 -P326 0.0352098144445432 V217 -A225 0.0351684500862177 T219 -C226 0.034850638596069 L275 -S283 0.0339865413096172 Q193 -L316 0.0339392644882421 P174 -C226 0.0339231636944552 V186 -S360 0.0334829961291976 Q182 -A225 0.0321406205635717 S179 -C323 0.0319864443337154 Q193 -Y212 0.0318450520093219 Q173 -I356 0.0299292612476951 W324 -I362 0.0299166170298935 W187 -I362 0.028996525350057 L275 -L325 0.0272485255224133 W180 -V357 0.0266164552660493 P174 -F221 0.0255482475397284 F188 -L316 0.025323815008407 V329 -T350 0.0244413374422399 L275 -N328 0.0235055032843814 Y172 -N353 0.022963140746342 Q182 -S272 0.0226885666495931 W324 -F351 0.0223152064075363 S179 -S185 0.021925803101154 D176 -A358 0.0215017776163364 N353 -S360 0.0214568662187897 S179 -C226 0.0211317210233171 R278 -Y320 0.0205058958506346 Q193 -H216 0.0197007064197724 A189 -I317 0.0191771170433861 A178 -V357 0.0182042644379401 A189 -N363 0.0176117278835708 H192 -I214 0.0175249960491708 Y172 -C226 0.0170717762332773 A189 -S213 0.0170194048101626 Q173 -H181 0.0168799148656099 K190 -S283 0.0165706718711078 H192 -I317 0.016567161602608 V184 -I362 0.0163985204854376 V329 -L352 0.0162709155104608 Y320 -N363 0.0162521180753529 H192 -S213 0.0161909848841497 A178 -A358 0.0161054829672755 S179 -N363 0.015977136866014 Y327 -S360 0.0159657482572344 S185 -F221 0.0159641333451368 L275 -I317 0.0156634429651317 N270 -S277 0.0154950256917515 H181 -L325 0.0154674072947623 T177 -S271 0.0151097171252998 W187 -F221 0.0150660844613477 Q182 -T319 0.0149775964168612 W187 -S213 0.0149562179166387 V186 -N359 0.014642806817255 E191 -T219 0.0144219337795182 L325 -Y354 0.0142277051681843 D176 -C226 0.0140193823842187 I214 -W222 0.0136986728249244 Q182 -Y215 0.0133559432265917 V217 -P224 0.0133096183997239 V186 -L282 0.0132354910467085 N270 -Y320 0.0132149088051694 V357 -N363 0.0128758347682503 Q182 -L316 0.0127917437433975 S213 -F221 0.0127557429648497 V186 -A225 0.012661108144238 N270 -N328 0.0122966968608651 H181 -I317 0.0121414284188117 F221 -N270 0.0117463626274144 W180 -V220 0.0116398826223425 S179 -F221 0.0113906433725144 V184 -V217 0.0111998566891574 S277 -Y320 0.0111912344442517 F188 -P284 0.0111338477537981 D176 -T350 0.0111258994895529 I317 -P326 0.0106436641952108 S185 -N359 0.0104850817301205 P224 -A269 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