############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:27:46 Total request time: 11.4 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|P29972|AQP1_HUMAN Aquaporin-1 OS=Homo sapiens GN=AQP1 PE=1 SV=3 Sequence length: 269 aa. Sequence: MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK TOPCONS predicted topology: iiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii OCTOPUS predicted topology: oooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Philius predicted topology: iiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii PolyPhobius predicted topology: iiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SCAMPI predicted topology: iiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SPOCTOPUS predicted topology: SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMiMMMMMMMMMMMMMMMooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii 4cskA: iiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMoooooooooooooooooooMMMMMMMMMMMMMMMMMMiiiLLLLLLLLLLLLLLiiiiiiiiiMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMiiiiiiiiiiMMMMMMMMMMMMMMMMMMooooLLLLLLLLLLLLLLoooooooMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 7.534 11 6.946 12 6.096 13 4.768 14 2.870 15 2.078 16 1.259 17 0.597 18 0.310 19 1.199 20 1.522 21 1.857 22 2.049 23 1.799 24 1.238 25 1.260 26 0.716 27 0.124 28 0.446 29 1.395 30 1.711 31 2.383 32 3.466 33 5.235 34 6.644 35 7.241 36 7.888 37 8.247 38 8.496 39 9.242 40 9.646 41 9.461 42 9.870 43 10.388 44 10.428 45 10.499 46 10.479 47 10.322 48 9.969 49 9.239 50 8.832 51 7.524 52 6.553 53 5.635 54 4.710 55 4.134 56 4.156 57 3.672 58 3.063 59 2.960 60 3.838 61 3.675 62 4.196 63 4.504 64 5.078 65 5.543 66 5.390 67 5.840 68 6.809 69 6.621 70 6.805 71 6.896 72 6.611 73 7.140 74 6.628 75 5.552 76 4.761 77 4.922 78 4.401 79 4.053 80 3.972 81 3.893 82 3.289 83 2.789 84 2.084 85 2.215 86 1.127 87 0.849 88 0.867 89 0.950 90 1.139 91 1.816 92 2.405 93 3.140 94 3.475 95 4.014 96 3.321 97 2.961 98 2.342 99 2.221 100 1.581 101 1.442 102 1.258 103 0.588 104 0.733 105 1.332 106 1.344 107 1.512 108 1.991 109 2.466 110 2.310 111 2.145 112 2.725 113 3.431 114 3.753 115 3.603 116 4.320 117 4.555 118 5.317 119 6.083 120 6.119 121 6.568 122 7.679 123 8.155 124 8.306 125 9.454 126 10.252 127 10.348 128 10.628 129 11.318 130 10.737 131 10.341 132 9.405 133 9.417 134 9.404 135 8.619 136 8.495 137 7.325 138 6.271 139 6.701 140 5.939 141 5.234 142 4.511 143 4.330 144 3.484 145 2.765 146 2.446 147 1.889 148 1.434 149 1.971 150 1.744 151 1.957 152 1.613 153 2.222 154 3.558 155 4.002 156 5.560 157 7.670 158 8.770 159 10.267 160 11.376 161 11.417 162 10.868 163 9.735 164 9.147 165 7.446 166 6.467 167 5.459 168 4.345 169 3.578 170 3.501 171 3.983 172 3.492 173 2.753 174 2.927 175 2.298 176 2.174 177 1.872 178 1.942 179 1.879 180 2.537 181 3.266 182 3.618 183 4.015 184 5.167 185 5.012 186 5.203 187 5.713 188 5.909 189 5.814 190 5.808 191 6.359 192 6.870 193 6.908 194 7.131 195 7.232 196 7.704 197 7.135 198 6.900 199 7.199 200 7.188 201 6.985 202 6.367 203 5.678 204 5.655 205 5.708 206 5.859 207 6.741 208 6.297 209 5.986 210 6.312 211 6.476 212 6.286 213 5.491 214 4.493 215 3.353 216 2.972 217 2.244 218 1.191 219 0.597 220 0.595 221 0.727 222 0.856 223 1.305 224 1.831 225 1.805 226 2.032 227 3.026 228 3.777 229 3.511 230 3.549 231 4.242 232 5.270 233 5.876 234 6.774 235 7.772 236 8.221 237 8.601 238 9.008 239 9.958 240 10.580 241 10.776 242 11.274 243 10.908 244 10.354 245 10.010 246 8.810 247 8.468 248 8.664 249 9.116 250 9.284 251 9.645 252 10.745 253 11.556 254 12.164 255 12.664 256 13.466 257 13.017 258 12.681 259 12.542 260 12.766 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 65.71 12 66.67 13 67.62 14 68.57 15 69.52 16 70.48 17 71.43 18 72.38 19 73.33 20 74.29 21 76.19 22 78.10 23 78.10 24 77.14 25 76.19 26 75.24 27 75.24 28 75.24 29 75.24 30 75.24 31 75.24 32 75.24 33 75.24 34 75.24 35 75.24 36 75.24 37 75.24 38 74.29 39 72.38 40 70.48 41 68.57 42 66.67 43 64.76 44 64.76 45 63.81 46 62.86 47 61.90 48 60.00 49 58.10 50 56.19 51 54.29 52 52.38 53 50.48 54 48.57 55 46.67 56 45.71 57 44.76 58 43.81 59 42.86 60 42.86 61 43.81 62 44.76 63 45.71 64 46.67 65 47.62 66 48.57 67 49.52 68 50.48 69 51.43 70 52.38 71 53.33 72 54.29 73 55.24 74 56.19 75 57.14 76 59.05 77 60.00 78 60.95 79 61.90 80 63.81 81 65.71 82 65.71 83 65.71 84 65.71 85 67.62 86 68.57 87 70.48 88 72.38 89 74.29 90 76.19 91 78.10 92 80.00 93 81.90 94 83.81 95 85.71 96 87.62 97 88.57 98 89.52 99 90.48 100 91.43 101 92.38 102 92.38 103 92.38 104 92.38 105 91.43 106 90.48 107 90.48 108 90.48 109 90.48 110 90.48 111 90.48 112 90.48 113 90.48 114 90.48 115 90.48 116 90.48 117 90.48 118 90.48 119 90.48 120 90.48 121 90.48 122 90.48 123 91.43 124 91.43 125 91.43 126 92.38 127 91.43 128 92.38 129 92.38 130 92.38 131 92.38 132 92.38 133 92.38 134 92.38 135 92.38 136 92.38 137 92.38 138 92.38 139 92.38 140 92.38 141 92.38 142 92.38 143 92.38 144 92.38 145 92.38 146 91.43 147 91.43 148 92.38 149 92.38 150 92.38 151 92.38 152 92.38 153 92.38 154 91.43 155 90.48 156 88.57 157 87.62 158 87.62 159 87.62 160 87.62 161 87.62 162 87.62 163 87.62 164 87.62 165 87.62 166 89.52 167 92.38 168 94.29 169 95.24 170 95.24 171 95.24 172 95.24 173 95.24 174 95.24 175 95.24 176 95.24 177 95.24 178 96.19 179 96.19 180 96.19 181 96.19 182 96.19 183 96.19 184 96.19 185 96.19 186 96.19 187 96.19 188 96.19 189 96.19 190 96.19 191 96.19 192 96.19 193 96.19 194 96.19 195 96.19 196 97.14 197 98.10 198 100.00 199 99.05 200 98.10 201 98.10 202 98.10 203 98.10 204 98.10 205 98.10 206 98.10 207 98.10 208 98.10 209 98.10 210 98.10 211 98.10 212 98.10 213 98.10 214 98.10 215 98.10 216 98.10 217 98.10 218 98.10 219 98.10 220 99.05 221 97.14 222 97.14 223 97.14 224 97.14 225 97.14 226 97.14 227 97.14 228 97.14 229 97.14 230 97.14 231 97.14 232 97.14 233 97.14 234 97.14 235 97.14 236 97.14 237 97.14 238 97.14 239 97.14 240 97.14 241 97.14 242 100.00 243 100.00 244 100.00 245 100.00 246 100.00 247 100.00 248 100.00 249 100.00 250 100.00 251 100.00 252 100.00 253 100.00 254 100.00 255 100.00 256 100.00 257 100.00 258 100.00 ##############################################################################