The protein contains 911 amino acids for an estimated molecular weight of 101792 Da.
Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. (updated: March 4, 2015)
Protein identification was indicated in the following studies:
The following articles were analysed to gather the proteome content of erythrocytes.
The gene or protein list provided in the studies were processed using the ID mapping API of Uniprot in September 2018. The number of proteins identified and mapped without ambiguity in these studies is indicated below.
Only Swiss-Prot entries (reviewed) were considered for protein evidence assignation.
Publication | Identification 1 | Uniprot mapping 2 | Not mapped / Obsolete | TrEMBL | Swiss-Prot |
---|---|---|---|---|---|
Goodman (2013) | 2289 (gene list) | 2278 | 53 | 20599 | 2269 |
Lange (2014) | 1234 | 1234 | 7 | 28 | 1224 |
Hegedus (2015) | 2638 | 2622 | 0 | 235 | 2387 |
Wilson (2016) | 1658 | 1528 | 170 | 291 | 1068 |
d'Alessandro (2017) | 1826 | 1817 | 2 | 0 | 1815 |
Bryk (2017) | 2090 | 2060 | 10 | 108 | 1942 |
Chu (2018) | 1853 | 1804 | 55 | 362 | 1387 |
1 as available in the article and/or in supplementary material
2 uniprot mapping returns all protein isoforms as one entry
The compilation of older studies can be retrieved from the Red Blood Cell Collection database.
The data and differentiation stages presented below come from the proteomic study and analysis performed by our partners of the GReX consortium, more details are available in their published work.
This protein is annotated as membranous in Gene Ontology, is annotated as membranous in UniProt, is predicted to be membranous by TOPCONS.
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The reference OMIM entry for this protein is 109270
The reference OMIM entry for this protein is 110500
A number sign (#) is used with this entry because of evidence that the blood group antigens of the Diego system are caused by a single amino acid variation in the SLC4A1 gene (109270), which encodes the erythrocyte band-3 protein. The Diego blood group system is controlled by 2 allelic genes: Di(a) and Di(b). The Di(a) antigen was first described in Venezuela on the basis of an antibody that had been the cause of hemolytic disease of the newborn (Levine et al., 1956). A second example of anti-Di(a) was found in Buffalo in the serum of a Polish mother, whose child also suffered from hemolytic disease of the newborn (Tatarsky et al., 1959). The Diego system shows polymorphism mainly in Mongolian peoples, e.g., Chinese and American Indians. In a family of Polish origin, Kusnierz-Alejska and Bochenek (1992) found anti-Di(a) antibody in the serum of a mother who gave birth to a newborn with severe hemolytic anemia. They identified the Di(a) antigen in 45 of 9,661 donor blood samples from different regions of Poland (0.46%). All 45 were of Polish ancestry. Zelinski et al. (1993) showed that the DI blood group is tightly linked to the erythrocyte surface protein band-3 locus (SLC4A1); maximum lod = 5.42 at theta = 0.00. Looser linkage between DI and D17S41 (maximum lod = 3.14 at theta = 0.09) for combined paternal and maternal meioses was also established. The EPB3 gene is located at 17q21-q22. Indeed, Bruce et al. (1994) demonstrated that the Di(a)/Di(b) polymorphism is a single amino acid substitution at position 854 of the band-3 protein, with proline of the wildtype band-3 protein corresponding to the Di(b) antigen and leucine to the Di(a) antigen (109270.0017). Data on gene frequencies of allelic variants were tabulated by Roychoudhury and Nei (1988). ... More on the omim web site
The reference OMIM entry for this protein is 601551
A number sign (#) is used with this entry because of evidence that the low-incidence Froese blood group antigen polymorphism is based on a change in the SLC4A1 (109270) gene, which encodes erythrocyte protein band-3, on chromosome 17q21.
The reference OMIM entry for this protein is 601550
A number sign (#) is used with this entry because of evidence that the Swann blood group antigens result from variation in the SLC4A1 gene (109270), which encodes the erythrocyte band-3 protein, on chromosome 17q21.
The reference OMIM entry for this protein is 112010
A number sign (#) is used with this entry because of evidence that Waldner blood group expression is caused by a point mutation in the SLC4A1 gene (109270). Lewis and Kaita (1981) found a 'new' red cell antigen in Hutterites of the surname Waldner. Zelinski et al. (1995) stated that the WD blood group antigen had been identified in Khoisans in South Africa and in a family in Holland. By genetic linkage analysis, they showed that WD is loosely linked to the reference marker D17S41 at 17q12-q24 and closely linked to the SLC4A1 locus at 17q12-q21. Bruce et al. (1995) demonstrated that the Wd(a) results from a substitution of methionine for valine-557 in erythrocyte band-3 (109270.0011). ... More on the omim web site
The reference OMIM entry for this protein is 112050
A number sign (#) is used with this entry because of evidence that the blood group Wright antigens are associated with a polymorphism in human erythrocyte band-3 (SLC4A1; 109270). The Wright antigen, a 'private' blood group (see 111500), was found by Holman (1953). Although it is very rare, the early date of its discovery and the ready availability of testing sera led to a large number of persons and variety of populations being tested. The frequency of the gene for the Wr(a) antigen was found to be about 3 in 10,000 among Europeans (Mourant et al., 1978). Because the Wr(b) antigen appeared to involve both red blood cell band-3 and glycophorin A (GPA; 111300), Bruce et al. (1995) examined the cDNA sequences of band-3 and GPA of 1 of the 2 known Wr(a+b-) individuals. They showed that this person was homozygous for a glu658-to-lys mutation in the BND3 gene, but had normal GPA. Putative heterozygotes with Wr(a+b+) RBCs had both glu and lys at residue 658 of band-3, whereas the common Wr(a-b+) RBC phenotype had only band-3 with glu658. Thus, the Wr(a) and Wr(b) antigens are determined by the amino acid at residue 658 of band-3 (109270.0006) and are antithetical. Bruce et al. (1995) proposed that arg61 of GPA interacts with glu658 of band-3 to form the Wr(b) antigen. ... More on the omim web site
The reference OMIM entry for this protein is 130600
A number sign (#) is used with this entry because of evidence that elliptocytosis-2 is caused by heterozygous mutation in the alpha-spectrin gene (SPTA1; 182860) on chromosome 1q23. For a general description and a discussion of genetic heterogeneity of elliptocytosis (HE), see EL1 (611804).
The reference OMIM entry for this protein is 166900
A number sign (#) is used with this entry because Southeast Asian ovalocytosis (SAO) is caused by a heterozyous 27-bp deletion in the SLC4A1 gene (109270) on chromosome 17q21.
The reference OMIM entry for this protein is 179800
A number sign (#) is used with this entry because autosomal dominant distal renal tubular acidosis has been found to be caused by mutation in the SLC4A1 gene (109270).
The reference OMIM entry for this protein is 185020
A number sign (#) is used with this entry because of evidence that cryohydrocytosis (CHC) is caused by heterozygous mutation in the SLC4A1 gene (109270) on chromosome 17q21. Heterozygous mutation in SLC4A1 can also cause Southeast Asian ovalocytosis (166900) and spherocytosis-4 (SPH4; 612653).
The reference OMIM entry for this protein is 611162
A number sign (#) is used with this entry because variation in several different genes influences susceptibility and resistance to malaria, as well as disease progression and severity. These genes include HBB (141900), ICAM1 (147840), CD36 (173510), CR1 (120620), GYPA (111300), GYPB (111740), GYPC (110750), TNF (191160), NOS2A (163730), TIRAP (606252), FCGR2B (604590), and CISH (602441). In addition, a locus associated with Plasmodium falciparum blood infection level has been mapped to chromosome 5q31-q33 (PFBI; 248310), a locus for susceptibility to mild malaria has been mapped to chromosome 6p21.3 (MALS; 609148), a locus associated with malaria fever episodes has been mapped to chromosome 10p15 (PFFE1; 611384), and a locus for susceptibility to placental malarial infection has been mapped to chromosome 6 (FUT9; 606865). Complete protection from Plasmodium vivax infection is associated with the Duffy blood group-negative phenotype (see 110700). Alpha(+)-thalassemia (141800), the X-linked disorder G6PD deficiency (300908), and Southeast Asian ovalocytosis (109270) are associated with resistance to malaria.
The reference OMIM entry for this protein is 611590
A number sign (#) is used with this entry because autosomal recessive distal renal tubular acidosis (dRTA) with hemolytic anemia is caused by mutation in the SLC4A1 gene (109270). For a general phenotypic description and a discussion of genetic heterogeneity of autosomal recessive distal RTA, see 267300.
The reference OMIM entry for this protein is 612653
A number sign (#) is used with this entry because spherocytosis type 4 is caused by mutation in the band 3 gene (SLC4A1, EPB3; 109270). For a general description and a discussion of genetic heterogeneity of spherocytosis, see SPH1 (182900).
July 2, 2021: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 2, 2021: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 2, 2021: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 1, 2021: Protein entry updated
Automatic update: OMIM entry 166900 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 612653 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 112010 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 112050 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 130600 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 109270 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 166900 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 179800 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 611590 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 185020 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 110500 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 601550 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 601551 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Feb. 16, 2021: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Feb. 16, 2021: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Feb. 16, 2021: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Feb. 16, 2021: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
April 25, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 4, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 601550 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 166900 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 109270 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 179800 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 110500 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 611162 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 185020 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 112010 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 611590 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 112050 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 130600 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 612653 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
Nov. 16, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Nov. 16, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 6, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
May 26, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 109270 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 110500 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 112010 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 112050 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 130600 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 166900 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 179800 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 185020 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 601550 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 601551 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 611162 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 611590 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 612653 was added.
Feb. 2, 2018: Protein entry updated
Automatic update: Uniprot description updated
Dec. 19, 2017: Protein entry updated
Automatic update: Uniprot description updated
Nov. 23, 2017: Protein entry updated
Automatic update: Uniprot description updated
March 16, 2016: Protein entry updated
Automatic update: OMIM entry 109270 was added.
Jan. 24, 2016: Protein entry updated
Automatic update: model status changed