PDB	PDB_resolution	refinement_method	refinement_TMscore	length	UniProt	UniProt_entry	organism	protein_name	contact_chain	contact_ligand	contact_ion	contact_nucleotide	no_contact	alpha%	beta%	coil%	DPF_sequence	DPF_SS	DPF_length	div_SE	div_MM	avg_RMSF	avg_gyration	ECOD_domain_ID	ECOD_architecture	ECOD_ID	ECOD_PDB_delineation	ECOD_renum_delineation	ECOD_X	ECOD_H	ECOD_T	ECOD_F	CATH_ID	CATH_PDB_delineation	CATH_renum_delineation	CATH_class	CATH_architecture	CATH_topology	CATH_supfamily	SCOP_PDB_delineation	SCOP_renum_delineation	SCOP_class	SCOP_fold	SCOP_supfamily	SCOP_family	SWORD_ID	SWORD_quality	SWORD_renum_delineation	SWORD_PDB_delineation	sequence
5zdb_A	1.972	-	-	253	Q9RZM4	Q9RZM4_DEIRA	D. radiodurans	Microbial-type PARG catalytic domain-containing protein	True	True	False	False	False	44	19	37	GGGFLGGAQAQ	HHHHCCCCCCH	11	0.924	0.876	0.99	17.56	e5zdbA1	"""a/b three-layered sandwiches"""	7529.1.1.8	29-281	1-253	"""-"""	"""-"""	"""Macro domain-like"""	"""DUF2263"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-253	29-281	VRLPGLAAMRQGTRLFTPEQGEDLREALRRRRGSFQTTCEVTSETTFAAARRLREKASALAALNFASAKNPGGGFLGGAQAQEEDLCRGSGLYFSLTSPQAEPYYAVNRQSHSALYTDHLIYSPQVPIFRDDAGQLLPAPVPVNIITAPAPNAGAVAQSRPEQLPQVLPTLRERARRVLGVAAWMEQTHLVLGAWGCGVFRNDPAGVARTFRELLEGEAQGAFEHVTFAVLDNHPQHPTLGAFRRELESLCLP
3n9s_A	1.85	-	-	307	D0IR47	D0IR47_HELP1	H. pylori	Fructose-bisphosphate aldolase	True	True	True	False	False	52	14	34	RLMGIEDNISVDEKDAV	CCCCCCCCCCCCCCCCC	17	0.934	0.912	0.87	19.73	e3n9sA1	"""a/b barrels"""	2002.1.1.63	1-307	1-307	"""TIM beta/alpha-barrel"""	"""-"""	"""TIM barrels"""	"""F_bP_aldolase"""	3.20.20.70	1-307	1-307	"""Alpha Beta"""	"""Alpha-Beta Barrel"""	"""TIM Barrel"""	"""Aldolase class I"""	1-307	1-307	"""Alpha and beta proteins (a/b)"""	"""TIM beta/alpha-barrel"""	"""Aldolase"""	"""-"""	Optimal • Dom. n°1	n/a	1-307	1-307	MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI
4lev_A	1.952	-	-	369	Q8N884	CGAS_HUMAN	H. sapiens	Cyclic GMP-AMP synthase	True	False	True	False	False	42	17	41	AKEGNGFQ	EECCCCEE	8	0.903	0.809	1.21	22.01	e4levA4, e4levA3	"""alpha arrays"", ""a+b three layers"""	102.1.3.18, 316.1.1.40	396-522, 154-395	243-369, 1-242	"""HhH/H2TH"", ""Nucleotidyltransferase-like"""	"""SAM/DNA-glycosylase"", ""-"""	"""PAP/OAS1 substrate-binding domain"", ""Nucleotidyltransferase"""	"""Mab-21_C"", ""Mab-21_N"""	1.10.1410.40, 3.30.460.90	154-174,330-356,379-522, 175-329,357-378	1-21,177-203,226-369, 22-176,204-225	"""Mainly Alpha"", ""Alpha Beta"""	"""Orthogonal Bundle"", ""2-Layer Sandwich"""	"""Poly(a)-polymerase, middle domain"", ""Beta Polymerase; domain 2"""	"""-"", ""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-369	154-522	FELDAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEF
4laf_A	1.761	-	-	207	C1I202	PNPB_PSEWB	P. sp.	p-benzoquinone reductase	True	True	False	False	False	39	19	42	MPEEVQVKSGIKGYRAA	CCHHHHHHHCHHHHHHC	17	0.852	0.82	1.45	16.85	e4lafA1	"""a/b three-layered sandwiches"""	2007.2.1.5	1-207	1-207	"""Flavodoxin-like"""	"""Flavoproteins/Phosphotyrosine protein phosphatases-like"""	"""Flavoproteins"""	"""FMN_red"""	3.40.50.360	1-207	1-207	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""-"""	1-207	1-207	"""Alpha and beta proteins (a/b)"""	"""Flavodoxin-like"""	"""Flavoproteins"""	"""-"""	Optimal • Dom. n°1	n/a	1-207	1-207	MPTKIQIVFYSSYGHIYKMAEAIAAGAREVGDVEVTLLQVPELMPEEVQVKSGIKGYRAAFGSIPYATPEVLAEADAIIFGTPTRFGNMCSQMRNFLDQTGGLWMSGGLIGKVGSVFTSTASQHGGQETTITSFHTTLLHHGMVIVGVPYSEPGLTNMTEISGGTPYGASTLAGADGSRQPSENELQIARFQGKHVATIAKRLANNK
3gmu_B	1.98	-	-	165	P35804	BLIP_STRCL	S. clavuligerus	Beta-lactamase inhibitory protein	False	False	True	False	False	19	35	46	YSSTGFYR	CCCCCCCC	8	0.824	0.829	1.25	16.53	e3gmuB1, e3gmuB2	"""a+b two layers"", ""a+b two layers"""	809.1.1.1, 809.1.1.1	1-79, 80-165	1-79, 80-165	"""BLIP-like"", ""BLIP-like"""	"""-"", ""-"""	"""beta-lactamase-inhibitor protein, BLIP"", ""beta-lactamase-inhibitor protein, BLIP"""	"""BLIP"", ""BLIP"""	3.30.1450.10, 3.30.1450.10	1-74, 75-165	1-74, 75-165	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""2-Layer Sandwich"""	"""Beta-lactamase Inhibitory Protein; Chain"", ""Beta-lactamase Inhibitory Protein; Chain"""	"""-"", ""-"""	1-165	1-165	"""Alpha and beta proteins (a+b)"""	"""BLIP-like"""	"""beta-lactamase-inhibitor protein, BLIP"""	"""beta-lactamase-inhibitor protein, BLIP"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-76, 77-165	1-76, 77-165	AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGFYRGSAHLWFTDGVLQGKRQWDLV
4ydr_A	1.6	-	-	304	F9VNG5	F9VNG5_SULTO	S. tokodaii	homoserine dehydrogenase	True	False	True	False	False	38	21	40	NRDLPKNEK	CCCCCCCCC	9	0.929	0.943	0.83	19.93	e4ydrA2, e4ydrA1	"""a+b two layers"", ""a/b three-layered sandwiches"""	298.1.1.10, 2003.1.1.46	134-304, 1-141	134-304, 1-141	"""FwdE/GAPDH domain-like"", ""Rossmann-like"""	"""-"", ""Rossmann-related"""	"""Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"", ""NAD(P)-binding Rossmann-fold domains"""	"""Homoserine_dh"", ""NAD_binding_3"""	3.30.360.10, 3.40.50.720	144-280, 1-143,281-304	144-280, 1-143,281-304	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""Dihydrodipicolinate Reductase; domain 2"", ""Rossmann fold"""	"""Dihydrodipicolinate Reductase; domain 2"", ""NAD(P)-binding Rossmann-like Domain"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-143,284-304, 144-283	1-143,284-304, 144-283	MKLLLFGYGNVGKAFRKLLHEKRSPELNDVIIGGIVTRRGIMLQDKEDFTPDLEGDVFKAFEKIKPDIIVDVSSANYNNGEPSLSLYKEAIKDGVNIITTNKAPLALAFNEIFSLARSKGVKIGFQGTVMSGTPSINLYRVLPGSRVIKIRGILNGTTNFILTLMNKGVSFEEALKEAQRRGYAEEDPTLDINGFDAAAKITILANFMIGNSVTIKDVKFEGINRDLPKNEKIKLIAYADEKEVWVKPLPISQDDPLYNVDGVENALEITTDIQSILIRGPGAGPVNAAYGALSDLILLKRDCL
1fx7_A	2.0	-	-	230	P9WMH1	IDER_MYCTU	M. tuberculosis	Iron-dependent repressor IdeR	True	False	True	False	False	46	15	39	GPEPGADDAN	CCCCCCCCCC	10	0.597	0.527	2.4	19.51	e1fx7A1, e1fx7A2, e1fx7A3	"""beta barrels"", ""alpha arrays"", ""alpha duplicates or obligate multimers"""	4.1.1.250, 101.1.2.45, 183.1.1.1	145-230, 2-64, 65-140	145-230, 2-64, 65-140	"""SH3"", ""HTH"", ""-"""	"""SH3"", ""HTH"", ""-"""	"""SH3"", ""winged"", ""Iron-dependent repressor protein, dimerization domain"""	"""FeoA_1"", ""Fe_dep_repress"", ""Fe_dep_repr_C"""	1.10.10.10, 1.10.60.10, 2.30.30.90	1-73, 74-143, 144-230	1-73, 74-143, 144-230	"""Mainly Alpha"", ""Mainly Alpha"", ""Mainly Beta"""	"""Orthogonal Bundle"", ""Orthogonal Bundle"", ""Roll"""	"""Arc Repressor Mutant, subunit A"", ""Diphtheria Toxin Repressor; domain 2"", ""SH3 type barrels."""	"""Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"", ""Iron dependent repressor, metal binding and dimerisation domain"", ""-"""	1-64, 65-144, 145-230	1-64, 65-144, 145-230	"""All alpha proteins"", ""All alpha proteins"", ""All beta proteins"""	"""DNA/RNA-binding 3-helical bundle"", ""Iron-dependent repressor protein, dimerization domain"", ""SH3-like barrel"""	"""'Winged helix' DNA-binding domain"", ""Iron-dependent repressor protein, dimerization domain"", ""C-terminal domain of transcriptional repressors"""	"""Iron-dependent repressor protein"", ""Iron-dependent repressor protein, dimerization domain"", ""FeoA-like"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	***, ***, ***	1-72, 73-147, 148-230	1-72, 73-147, 148-230	MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMERDGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLDELGVGPEPGADDANLVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETTPGGGVTIVIPGHENVTLPHEMAHAVKVEKV
2z8i_B	1.65	-	-	190	P18956	GGT_ECOLI	E. coli	Glutathione hydrolase proenzyme	True	True	False	False	False	21	24	56	PGVPNVYGLVGG	CCCCCCCCCCCC	12	0.599	0.597	3.38	18.79	e2z8iB1	"""a+b four layers"""	210.1.6.1	391-580	1-190	"""Ntn/PP2C"""	"""Ntn"""	"""Gamma-glutamyltranspeptidase-like"""	"""G_glu_transpept"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-190	391-580	TTHYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEATNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLTAGY
6oux_A	1.94	-	-	393	-	-	S. multivorans	Lyase	True	False	False	False	False	44	14	42	LKQNAGSHSPSMEDLKK	CCCCCCCCCCCHHHHHH	17	0.923	0.901	1.05	22.43	e6ouxA2	"""a+b two layers"""	3016.1.1.35	288-392	289-393	"""-"""	"""-"""	"""C-terminal domain in some PLP-dependent transferases"""	"""Aminotran_1_2_C_12"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	***, ***, ***	1-50,304-393, 51-107,241-303, 108-240	0-49,303-392, 50-106,240-302, 107-239	ASVDTMNARNTQFTKAFHALKQNAGSHSPSMEDLKKMFPTLEIKIDACYLSNPYASELVLDYIDRELIQTNAYKKVLTHYPSQQRSLQKVMAESLHVKPENIFIGNGATEIIQMLLQQEEVQKVALMIPTFSSYYEFVGKGCEVVYFPLNERDDYSFDADKYCQFIENEQPDTVVLINPNNPNGAYLSLEKMHILLKRLAFVPRIIIDESFIHFAYEDEALTCLSSTVLFDMYPNVIIVKSLSKDFGIAGVRLGYALMDSRKIDALLEHGFLWNINGIGEYCLRLFVREDFLKRYEEARKQYIKEMCRFKEALLGIENVYVYPSMANFVMLKLPSRIKASFVISALLVEYGIYVRTMADKIGVEGECIRIAGRTREENNCIVMALKSILKDSK
2x8m_A	1.85	-	-	311	Q8DR52	Q8DR52_STRR6	S. pneumoniae	Choline-binding protein F	False	True	True	False	False	1	46	53	VTIDIDRSK	ECCCECCCC	9	0.631	0.548	2.07	32.28	e2x8mA1	"""beta duplicates or obligate multimers"""	702.1.1.10	1-311	1-311	"""-"""	"""-"""	"""beta-hairpin stack"""	"""CW_binding_1"""	2.10.270.10, 2.10.270.20	129-311, 1-128	129-311, 1-128	"""Mainly Beta"", ""Mainly Beta"""	"""Ribbon"", ""Ribbon"""	"""left handed beta-beta-3-solenoid"", ""left handed beta-beta-3-solenoid"""	"""Cholin Binding"", ""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	****, ****, ****	1-127, 128-252, 253-311	1-127, 128-252, 253-311	NTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYEDGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKMLTDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSGAMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNGEWVQ
2e2d_A	2.0	-	-	165	P45452	MMP13_HUMAN	H. sapiens	Collagenase 3	True	False	True	False	False	25	18	57	YTGKSHFML	CCCCCCCCC	9	0.807	0.777	1.45	15.67	e2e2dA1	"""mixed a+b and a/b"""	2498.1.1.124	110-267	7-164	"""Zincin-like"""	"""-"""	"""Metalloproteases (""zincins"") catalytic domain"""	"""Peptidase_M10"""	3.40.390.10	104-268	1-165	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Collagenase (Catalytic Domain)"""	"""Collagenase (Catalytic Domain)"""	104-268	1-165	"""Alpha and beta proteins (a+b)"""	"""Zincin-like"""	"""Metalloproteases ('zincins'), catalytic domain"""	"""Matrix metalloproteases, catalytic domain"""	Optimal • Dom. n°1	n/a	1-165	104-268	YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP
1tyz_C	2.0	-	-	338	Q00740	1A1D_PSEUD	P. sp.	1-aminocyclopropane-1-carboxylate deaminase	True	True	True	False	False	46	16	38	PDGFDIGFRR	CCCCCHHHHC	10	0.916	0.908	0.88	19.79	e1tyzC2, e1tyzC1	"""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"""	2003.4.1.5, 2003.4.1.5	1-169, 170-338	1-169, 170-338	"""Rossmann-like"", ""Rossmann-like"""	"""-"", ""-"""	"""Tryptophan synthase beta subunit-like PLP-dependent enzymes"", ""Tryptophan synthase beta subunit-like PLP-dependent enzymes"""	"""PALP"", ""PALP"""	3.40.50.1100, 3.40.50.1100	1-45,165-338, 66-164	1-45,165-338, 66-164	"""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""3-Layer(aba) Sandwich"""	"""Rossmann fold"", ""Rossmann fold"""	"""-"", ""-"""	1-338	1-338	"""Alpha and beta proteins (a/b)"""	"""Tryptophan synthase beta subunit-like PLP-dependent enzymes"""	"""Tryptophan synthase beta subunit-like PLP-dependent enzymes"""	"""Tryptophan synthase beta subunit-like PLP-dependent enzymes"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-60,162-338, 61-161	1-60,162-338, 61-161	MNLQRFPRYPLTFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIPEALAQGCDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVRLVPDGFDIGFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAELGFKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTREQITRIARQTAEKVGLERDIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEGKSMHGMIEMVRNGEFPEGSRVLYAHLGGVPALNGYSFIFRDG
1k4k_A	2.0	-	-	213	P0A752	NADD_ECOLI	E. coli	Nicotinate-nucleotide adenylyltransferase	True	True	False	False	False	42	15	43	LTFPTWYEY	HCCCCCCCH	9	0.901	0.848	0.98	17.84	e1k4kA1	"""a/b three-layered sandwiches"""	2005.1.1.218	1-213	1-213	"""HUP domain-like"""	"""-"""	"""HUP domains"""	"""CTP_transf_like"""	3.40.50.620	1-213	1-213	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""HUPs"""	1-213	1-213	"""Alpha and beta proteins (a/b)"""	"""Adenine nucleotide alpha hydrolase-like"""	"""Nucleotidylyl transferase"""	"""Adenylyltransferase"""	Optimal • Dom. n°1	n/a	1-213	1-213	MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
7jx6_A	1.61	-	-	104	P0DTC8	NS8_SARS2	S. acute respiratory syndrome coronavirus 2	ORF8 protein	True	False	True	False	False	0	47	53	DEAGSKSPIQYIDIGN	ECCCCEEECCCCCCCC	16	0.773	0.707	1.13	13.78	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-104	18-121	QECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRVVLDFI
4z49_B	1.7	-	-	282	P49327	FAS_HUMAN	H. sapiens	Fatty acid synthase	True	False	True	False	False	46	12	42	LAYTQSYRAKLTP	HHHHHHHHCCCCC	13	0.932	0.827	0.94	19.38	e4z49B1	"""a/b three-layered sandwiches"""	7579.1.1.37	2221-2502	1-282	"""-"""	"""-"""	"""alpha/beta-Hydrolases"""	"""UNK_F_TYPE"""	1.10.1470.20, 3.40.50.1820	2343-2432, 2221-2342,2433-2502	123-212, 1-122,213-282	"""Mainly Alpha"", ""Alpha Beta"""	"""Orthogonal Bundle"", ""3-Layer(aba) Sandwich"""	"""Protein Yjbj; Chain"", ""Rossmann fold"""	"""Fatty acid synthase; domain 2"", ""alpha/beta hydrolase"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-134,205-282, 135-204	2221-2354,2425-2502, 2355-2424	SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLA
1y57_A	1.91	-	-	452	P12931	SRC_HUMAN	H. sapiens	Proto-oncogene tyrosine-protein kinase Src	False	True	True	False	False	31	23	46	LIEDNEYTARQGAK	ECCCCCCCCCCCCC	14	0.568	0.55	3.47	30.22	e1y57A1, e1y57A2, e1y57A3	"""beta barrels"", ""a+b two layers"", ""a+b complex topology"""	4.1.1.116, 214.1.1.26, 206.1.1.24	85-140, 143-246, 253-524	4-59, 62-165, 172-443	"""SH3"", ""-"", ""-"""	"""SH3"", ""-"", ""Protein kinase/SAICAR synthase/ATP-grasp"""	"""SH3"", ""SH2"", ""Protein kinase"""	"""SH3_1"", ""SH2"", ""Pkinase_Tyr"""	1.10.510.10, 2.30.30.40, 3.30.200.20, 3.30.505.10	345-523, 82-145, 259-344, 146-247	264-442, 1-64, 178-263, 65-166	"""Mainly Alpha"", ""Mainly Beta"", ""Alpha Beta"", ""Alpha Beta"""	"""Orthogonal Bundle"", ""Roll"", ""2-Layer Sandwich"", ""2-Layer Sandwich"""	"""Transferase(Phosphotransferase); domain 1"", ""SH3 type barrels."", ""Phosphorylase Kinase; domain 1"", ""SHC Adaptor Protein"""	"""Transferase(Phosphotransferase) domain 1"", ""SH3 Domains"", ""Phosphorylase Kinase; domain 1"", ""SH2 domain"""	83-145, 146-248, 249-533	2-64, 65-167, 168-452	"""All beta proteins"", ""Alpha and beta proteins (a+b)"", ""Alpha and beta proteins (a+b)"""	"""SH3-like barrel"", ""SH2-like"", ""Protein kinase-like (PK-like)"""	"""SH3-domain"", ""SH2 domain"", ""Protein kinase-like (PK-like)"""	"""SH3-domain"", ""SH2 domain"", ""Protein kinases, catalytic subunit"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3, Optimal • Dom. n°4	***, ***, ***, ***	1-66, 67-177, 178-259, 260-452	82-147, 148-258, 259-340, 341-533	MVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
1ekf_A	1.95	-	-	365	O15382	BCAT2_HUMAN	H. sapiens	Branched-chain-amino-acid aminotransferase, mitochondrial	True	True	False	False	False	25	28	47	QKPHKKPGPGEPLVFGK	CCCCCCCCCCCCCCCCC	17	0.854	0.777	1.1	22.01	e1ekfA2, e1ekfA1	"""a+b two layers"", ""a+b two layers"""	4020.1.1.2, 4045.1.1.2	3-171, 172-364	3-171, 172-364	"""-"", ""-"""	"""-"", ""-"""	"""a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes"", ""barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes"""	"""Aminotran_4_N"", ""Aminotran_4_C"""	3.20.10.10, 3.30.470.10	175-350, 1-174,351-365	175-350, 1-174,351-365	"""Alpha Beta"", ""Alpha Beta"""	"""Alpha-Beta Barrel"", ""2-Layer Sandwich"""	"""D-amino Acid Aminotransferase; Chain A, domain 2"", ""D-amino Acid Aminotransferase; Chain A, domain 1"""	"""D-amino Acid Aminotransferase, subunit A, domain 2"", ""-"""	1-365	1-365	"""Multi-domain proteins (alpha and beta)"""	"""D-aminoacid aminotransferase-like PLP-dependent enzymes"""	"""D-aminoacid aminotransferase-like PLP-dependent enzymes"""	"""D-aminoacid aminotransferase-like PLP-dependent enzymes"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-178,350-365, 179-349	1-178,350-365, 179-349	ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPRRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV
3p8t_A	1.78	-	-	294	Q9V228	Q9V228_PYRAB	P. abyssi	AsnS-like asparaginyl-tRNA synthetase related protein	True	False	False	False	False	37	23	40	WPDPAGEGI	CCCCCCCCC	9	0.89	0.886	1.04	19.59	e3p8tA1	"""a+b three layers"""	314.1.1.5	1-294	1-294	"""-"""	"""-"""	"""Class II aaRS and biotin synthetases"""	"""tRNA-synt_2"""	3.30.930.10	1-294	1-294	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""BirA Bifunctional Protein; domain 2"""	"""Bira Bifunctional Protein; Domain 2"""	1-294	1-294	"""Alpha and beta proteins (a+b)"""	"""Class II aaRS and biotin synthetases"""	"""Class II aaRS and biotin synthetases"""	"""Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain"""	Optimal • Dom. n°1	n/a	1-294	1-294	MNAVEIISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPAGEGIRPAEVDVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMRLIEELIYGLFRKAEEWTGREFPRARHFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDREENGVWKNYDLILPYGYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI
1jmk_O	1.71	-	-	230	Q08787	SRFAC_BACSU	B. subtilis	Surfactin synthase subunit 3	True	False	True	False	False	35	20	45	DLDGRTVE	CCCCCCHH	8	0.896	0.872	1.09	16.96	e1jmkO1	"""a/b three-layered sandwiches"""	7579.1.1.3	2-231	1-230	"""-"""	"""-"""	"""alpha/beta-Hydrolases"""	"""Hydrolase_4_1"""	1.10.287.490, 3.40.50.1820	112-166, 2-111,167-228	111-165, 1-110,166-227	"""Mainly Alpha"", ""Alpha Beta"""	"""Orthogonal Bundle"", ""3-Layer(aba) Sandwich"""	"""Helix Hairpins"", ""Rossmann fold"""	"""Helix hairpin bin"", ""alpha/beta hydrolase"""	2-231	1-230	"""Alpha and beta proteins (a/b)"""	"""alpha/beta-Hydrolases"""	"""alpha/beta-Hydrolases"""	"""Thioesterase domain of polypeptide, polyketide and fatty acid synthases"""	Optimal • Dom. n°1	n/a	1-230	2-231	GGSDGLQDVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQKLQPEGPLTLFGYSAGCSLAFEAAKKLEGQGRIVQRIIMVDSYKKQGVSDLDGRTVESDVEALMNVNRDNEALNSEAVKHGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDIPEWLASWEEATTGAYRMKRGFGTHAEMLQGETLDRNAGILLEFLNTQT
6wcs_A	1.87	-	-	438	Q9FH97	EPS1_ARATH	A. thaliana	Protein ENHANCED PSEUDOMONAS SUSCEPTIBILITY 1	True	True	False	False	False	29	24	47	TKPTSYVTTP	HCCCCCCCCC	10	0.927	0.939	0.94	22.19	e6wcsA1, e6wcsA2	"""a+b complex topology"", ""a+b complex topology"""	323.1.1.36, 323.1.1.37	217-434, -3-216	221-438, 1-220	"""-"", ""-"""	"""-"", ""-"""	"""CoA-dependent acyltransferases"", ""CoA-dependent acyltransferases"""	"""Transferase_C"", ""Transferase_N"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-438	-3-434	AAHGMEEELVVISKSIVNPRSLKKPTSVKKIQLTPWDLSRLRFGYLQRGLLFHKIEVKQLQASLSVALDRFYPLAGRLVKLKNDDDTVSFFISCDGSGVEFVHAVAKNIELSDVLELSGSVPGFFASFFPATGIKNYHGVSRSLLMVQVTEMKDGVFIGFGYNSTVADATSIWKFINAWSEICSKDSSGSQTFQRRLHLKGWFFDEIDYPIHIPDPETKPTSYVTTPTNLQEKMFHVTKENVLKLDAKANDEADQKISSIQAVLAYIWRSMVKHSGMSREEETHCRLPINMRQRLNPPLEEECFGNVSQTGIATVTVGELLDHGLGWAAMQINNMELSQTDEKAKAFAENWVKNIKIPVSVGSKDLVVTNSHRFDVYCNDFGWGKPIAARAGPPYLNGRLVVFKGIGEASLDFQACLLPQVVEKLVKDAEFNEYVSIV
2dve_A	1.6	-	-	235	O57883	O57883_PYRHO	P. horikoshii	235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase	True	False	False	True	False	29	31	40	GHGRLNAKWE	CECHHHCECC	10	0.92	0.886	0.86	17.69	e2dveA1, e2dveA2	"""beta barrels"", ""a+b three layers"""	4.1.1.8, 314.1.1.44	189-235, 1-188	189-235, 1-188	"""SH3"", ""-"""	"""SH3"", ""-"""	"""SH3"", ""Class II aaRS and biotin synthetases"""	"""BPL_C"", ""BPL_LplA_LipB"""	2.30.30.100, 3.30.930.10	188-235, 1-187	188-235, 1-187	"""Mainly Beta"", ""Alpha Beta"""	"""Roll"", ""2-Layer Sandwich"""	"""SH3 type barrels."", ""BirA Bifunctional Protein; domain 2"""	"""-"", ""Bira Bifunctional Protein; Domain 2"""	189-235, 1-188	189-235, 1-188	"""All beta proteins"", ""Alpha and beta proteins (a+b)"""	"""SH3-like barrel"", ""Class II aaRS and biotin synthetases"""	"""C-terminal domain of transcriptional repressors"", ""Class II aaRS and biotin synthetases"""	"""Biotin repressor (BirA)"", ""Biotin holoenzyme synthetase"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-187, 188-235	1-187, 188-235	MLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMGHGRLNAKWESPEGGLWLSIVLSPKVPQKDLPKIVFLGAVGVVETLKEFSIDGRIKWPNDVLVNYKKIAGVLVEGKGDKIVLGIGLNVNNKVPNGATSMKLELGSEVPLLSVFRSLITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSLRFL
3cr6_A	1.22	-	-	137	P29373	RABP2_HUMAN	H. sapiens	Cellular retinoic acid-binding protein 2	False	True	False	False	False	13	56	31	VMLRKIEVAAASK	HHHHHHHHHHHCC	13	0.82	0.895	1.02	15.06	e3cr6A1	"""beta barrels"""	9.1.1.12	1-137	1-137	"""Lipocalins/Streptavidin"""	"""-"""	"""Lipocalins"""	"""Lipocalin_7"""	2.40.128.20	1-137	1-137	"""Mainly Beta"""	"""Beta Barrel"""	"""Lipocalin"""	"""-"""	1-137	1-137	"""All beta proteins"""	"""Lipocalins"""	"""Lipocalins"""	"""Fatty acid binding protein-like"""	Optimal • Dom. n°1	n/a	1-137	1-137	PNFSGNWKIIRSENFEELLKVLGVNVMLRKIEVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTLELTNDGELILTMTADDVVCTKVYVRE
1x54_A	1.45	-	-	434	O57980	SYN_PYRHO	P. horikoshii	Asparagine--tRNA ligase	False	True	True	False	False	35	28	37	GAVEGGAT	CCCCCHHH	8	0.757	0.708	2.46	26.94	e1x54A1, e1x54A2	"""beta barrels"", ""a+b three layers"""	2.1.1.63, 314.1.1.5	1-104, 105-434	1-104, 105-434	"""OB-fold"", ""-"""	"""-"", ""-"""	"""Nucleic acid-binding proteins"", ""Class II aaRS and biotin synthetases"""	"""tRNA_anti-codon"", ""tRNA-synt_2"""	2.40.50.140, 3.30.930.10	1-104, 105-434	1-104, 105-434	"""Mainly Beta"", ""Alpha Beta"""	"""Beta Barrel"", ""2-Layer Sandwich"""	"""OB fold (Dihydrolipoamide Acetyltransferase, E2P)"", ""BirA Bifunctional Protein; domain 2"""	"""Nucleic acid-binding proteins"", ""Bira Bifunctional Protein; Domain 2"""	1-104, 105-434	1-104, 105-434	"""All beta proteins"", ""Alpha and beta proteins (a+b)"""	"""OB-fold"", ""Class II aaRS and biotin synthetases"""	"""Nucleic acid-binding proteins"", ""Class II aaRS and biotin synthetases"""	"""-"", ""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	*****, *****	1-104, 105-434	1-104, 105-434	MIEKVYCQEVKPELDGKKVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVVGEETFEKAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPEQASPELLLDYRHLHIRTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPILVTGAVEGGATLFKLKYFDKYAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIDILQSKGVNVEWGDDLGADEERVLTEEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLASDMLAPEGYGEIIGGSQREDDYDKLLNRILEEGMDPKDYEWYLDLRRYGSVPHSGFGLGVERLVAWVLKLDHIRWAALFPRTPARLYP
2eb6_A	1.69	-	-	267	Q46982	Q46982_ECOLX	E. coli	2-hydroxyhexa-2,4-dienoate hydratase	True	False	True	False	False	33	30	37	DPETQRPR	CCCCCCEC	8	0.838	0.758	1.08	18.66	e2eb6A1	"""beta sandwiches"""	11.9.1.3	1-267	1-267	"""Immunoglobulin-like beta-sandwich"""	"""-"""	"""FAH"""	"""FAA_hydrolase"""	3.90.850.10	1-267	1-267	"""Alpha Beta"""	"""Alpha-Beta Complex"""	"""Fumarylacetoacetate hydrolase; domain 2"""	"""Fumarylacetoacetase-like, C-terminal domain"""	1-267	1-267	"""Alpha and beta proteins (a+b)"""	"""FAH"""	"""FAH"""	"""-"""	Optimal • Dom. n°1	n/a	1-267	1-267	MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIDPETQRPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV
5o0j_A	1.81	-	-	453	O58328	GLKA_PYRHO	P. horikoshii	ADP-dependent glucose/glucosamine kinase	False	True	False	False	False	46	21	34	VVKKPKSTV	CCCCCCCCC	9	0.801	0.934	1.28	23.01	e5o0jA1	"""a/b three-layered sandwiches"""	2003.6.1.1	5-457	1-453	"""Rossmann-like"""	"""-"""	"""Ribokinase-like"""	"""ADP_PFK_GK"""	3.30.1110.20, 3.40.1190.20	36-113,177-204, 5-35,114-176,206-454	32-109,173-200, 1-31,110-172,202-450	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""Adenosine kinase, small domain"", ""UDP-N-acetylmuramoyl-L-alanine"""	"""-"", ""-"""	5-457	1-453	"""Alpha and beta proteins (a/b)"""	"""Ribokinase-like"""	"""Ribokinase-like"""	"""ADP-specific Phosphofructokinase/Glucokinase"""	Optimal • Dom. n°1	n/a	1-453	5-457	TNWESLYEKALDKVEASIRKVRGVLLAYNTNIDAIKYLKREDLEKRIEKVGKEEVLRYSEELPKEIETIPQLLGSILWSIKRGKAAELLVVSREVREYMRKWGWDELRMGGQVGIMANLLGGVYGIPVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKGEEDCIHYIYEFPRNFKVLDFEAPRENRFIGAADDYNPILYVREEWIERFEEIAKRSELAIISGLHPLTQENHGKPIKLVREHLKILNDLGIRAHLEFAFTPDEVVRLEIVKLLKHFYSVGLNEVELASVVSVMGEKELAERIISKDPADPIAVIEGLLKLIKETGVKRIHFHTYGYYLALTREKGEHVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGLEVEKILEKEFSLRDGIGSIEDYQLTFIPTKVVKKPKSTVGIGDTISSSAFVSEFSLH
6g6x_A	1.13	-	-	236	P31947	1433S_HUMAN	H. sapiens	14-3-3 protein sigma	True	False	True	False	False	81	0	19	KSNEEGSEEK	HHCCCCCCCC	10	0.87	0.823	1.09	19.89	e6g6xA1	"""alpha superhelices"""	109.4.1.1	-4-231	1-236	"""Repetitive alpha hairpins"""	"""-"""	"""ARM repeat"""	"""14-3-3"""	1.20.190.20	-4-231	1-236	"""Mainly Alpha"""	"""Up-down Bundle"""	"""Delta-Endotoxin; domain 1"""	"""14-3-3 domain"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	****, ****, ****	1-56, 57-167, 168-236	-4-51, 52-162, 163-231	GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
4ixe_D	1.54	-	-	206	P16184	DYR_PNECA	P. carinii	Dihydrofolate reductase	False	True	False	False	False	25	31	44	ESLDLGNG	CCCCCCCC	8	0.865	0.874	1.04	17.29	e4ixeD1	"""a/b three-layered sandwiches"""	7501.1.1.1	1-206	1-206	"""-"""	"""-"""	"""Dihydrofolate reductases"""	"""DHFR_1"""	3.40.430.10	1-206	1-206	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Dihydrofolate Reductase, subunit A"""	"""Dihydrofolate Reductase, subunit A"""	1-206	1-206	"""Alpha and beta proteins (a/b)"""	"""Dihydrofolate reductase-like"""	"""Dihydrofolate reductase-like"""	"""Dihydrofolate reductases"""	Optimal • Dom. n°1	n/a	1-206	1-206	MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
5h2a_A	1.9	-	-	271	Q6CUK7	Q6CUK7_KLULA	K. lactis	KLLA0C04147p	True	False	False	False	False	58	0	42	SSKEQNDK	CHHHCCCH	8	0.704	0.779	2.23	26.61	e5h2aA1	"""alpha superhelices"""	109.3.1.8	4-274	7-271	"""Repetitive alpha hairpins"""	"""-"""	"""Ankyrin repeat"""	"""Ank_2"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-149, 150-271	4-152, 153-274	GSAMGSTVSVSKPLLKLKLLDCLRQSNFQQLCHLIANEFQPFDEPTVRSVFELILHYAVQVSPASLIKDIVQNWTTKGSSNSQLFIDVNKQDQDGNTPLHLAAFQSRGDVVTVLMNHPDINDCILNDAHLQPIEMCKNLNIAQMMQVARANYVAEIAQEFRQAFNNRDIDHLNSILSNPRNQELLDINGMEPETGDTVLHEFVKKRDILLCRWILDHGGDPFKRDSRGKLPIDLLKKVSSKEQNDKKNAIDLELKKMLEKAAREQSVIDVT
3zwq_A	2.0	-	-	313	A3MVR4	A3MVR4_PYRCJ	P. calidifontis	Alpha/beta hydrolase fold-3 domain protein	True	False	False	False	False	42	18	40	AAQLQFRP	CCCCCCCC	8	0.958	0.91	0.75	18.51	e3zwqA1	"""a/b three-layered sandwiches"""	7579.1.1.2	1-313	1-313	"""-"""	"""-"""	"""alpha/beta-Hydrolases"""	"""Hydrolase_4"""	3.40.50.1820	1-313	1-313	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""alpha/beta hydrolase"""	1-313	1-313	"""Alpha and beta proteins (a/b)"""	"""alpha/beta-Hydrolases"""	"""alpha/beta-Hydrolases"""	"""-"""	Optimal • Dom. n°1	n/a	1-313	1-313	MPLSPILRQILQQLAAQLQFRPDMDVKTVREQFEKSSLILVKMANEPIHRVEDITIPGRGGPIRARVYRPRDGERLPAVVYYHGGGFVLGSVETHDHVCRRLANLSGAVVVSVDYRLAPEHKFPAAVEDAYDAAKWVADNYDKLGVDNGKIAVAGDSAGGNLAAVTAIMARDRGESFVKYQVLIYPAVNLTGSPTVSRVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPYASPIFADLSNLPPALVITAEYDPLRDEGELYAHLLKTRGVRAVAVRYNGVIHGFVNFYPILEEGREAVSQIAASIKSMAVA
6rmk_A	1.8	-	-	231	P02945	BACR_HALSA	H. salinarum	Bacteriorhodopsin	False	True	False	False	False	78	5	17	FTSKAESMRPE	CHHHHCCCCHH	11	0.82	0.843	1.25	18.95	e6rmkA1	"""alpha bundles"""	5001.1.1.7	4-234	1-231	"""-"""	"""-"""	"""Family A G protein-coupled receptor-like"""	"""Bac_rhodopsin"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	4-234	1-231	"""Membrane and cell surface proteins and peptides"""	"""Class A G protein-coupled receptor (GPCR)-like"""	"""Class A G protein-coupled receptor (GPCR)-like"""	"""Bacteriorhodopsin-like"""	Optimal • Dom. n°1	n/a	1-231	4-234	ITGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRSRAIFGEAE
2qos_C	1.81	-	-	173	P07357	CO8A_HUMAN	H. sapiens	Complement component C8 alpha chain	True	False	False	False	False	18	43	39	FLQEQGHR	HHHHHHHH	8	0.888	0.826	0.98	15.68	e2qosC1	"""beta barrels"""	9.1.1.10	10-182	1-173	"""Lipocalins/Streptavidin"""	"""-"""	"""Lipocalins"""	"""Lipocalin"""	2.40.128.20	10-182	1-173	"""Mainly Beta"""	"""Beta Barrel"""	"""Lipocalin"""	"""-"""	10-182	1-173	"""All beta proteins"""	"""Lipocalins"""	"""Lipocalins"""	"""Retinol binding protein-like"""	Optimal • Dom. n°1	n/a	1-173	10-182	ASPISTIQPKANFDAQQFAGTWLLVAVGSAARFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARGARGAVHVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR
1jg6_A	1.9	-	-	351	P04547	GSTB_BPT4	E. phage T4	DNA beta-glucosyltransferase	False	False	False	True	False	39	18	43	WPNVKNRPW	HHHHCCCCC	9	0.915	0.898	0.95	21.89	e1jg6A2, e1jg6A1	"""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"""	7512.1.1.8, 7512.1.1.13	171-351, 1-170	171-351, 1-170	"""-"", ""-"""	"""-"", ""-"""	"""UDP-Glycosyltransferase/glycogen phosphorylase"", ""UDP-Glycosyltransferase/glycogen phosphorylase"""	"""Glyco_trans_1_2_like"", ""T4-Gluco-transf"""	3.40.50.2000, 3.40.50.2000	1-166,333-349, 167-332	1-166,333-349, 167-332	"""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""3-Layer(aba) Sandwich"""	"""Rossmann fold"", ""Rossmann fold"""	"""Glycogen Phosphorylase B;"", ""Glycogen Phosphorylase B;"""	1-351	1-351	"""Alpha and beta proteins (a/b)"""	"""UDP-Glycosyltransferase/glycogen phosphorylase"""	"""UDP-Glycosyltransferase/glycogen phosphorylase"""	"""beta-Glucosyltransferase (DNA-modifying)"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-172,337-351, 173-336	1-172,337-351, 173-336	MKIAIINMGNNVINFKTVPSSETIYLFKVISEMGLNVDIISLKNGVYTKSFDEVDVNDYDRLIVVNSSINFFGGKPNLAILSAQKFMAKYKSKIYYLFTDIRLPFSQSWPNVKNRPWAYLYTEEELLIKSPIKVISQGINLDIAKAAHKKVDNVIEFEYFPIEQYKIHMNDFQLSKPTKKTLDVIYGGSFRSGQRESKMVEFLFDTGLNIEFFGNAREKQFKNPKYPWTKAPVFTGKIPMNMVSEKNSQAIAALIIGDKNYNDNFITLRVWETMASDAVMLIDEEFDTKHRIINDARFYVNNRAELIDRVNELKHSDVLRKEMLSIQHDILNKTRAKKAEWQDAFKKAIDL
1w2f_A	1.8	-	-	276	P23677	IP3KA_HUMAN	H. sapiens	Inositol-trisphosphate 3-kinase A	True	False	True	False	False	39	22	39	EAPTEEEHAQR	CCCCHHHHHHC	11	0.85	0.765	1.24	19.5	e1w2fA1	"""a+b complex topology"""	206.1.2.2	186-461	1-276	"""-"""	"""Protein kinase/SAICAR synthase/ATP-grasp"""	"""SAICAR synthase"""	"""IPK"""	3.30.470.160	187-461	2-276	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""D-amino Acid Aminotransferase; Chain A, domain 1"""	"""Inositol polyphosphate kinase"""	186-461	1-276	"""Alpha and beta proteins (a+b)"""	"""SAICAR synthase-like"""	"""SAICAR synthase-like"""	"""Inositol polyphosphate kinase (IPK)"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-84,134-276, 85-133	186-269,319-461, 270-318	MSWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER
2xrl_A	1.85	-	-	207	P0ACT4	TETR4_ECOLX	E. coli	Tetracycline repressor protein class D	False	True	True	False	False	73	0	27	AALTDRPAAPDE	HHHHHCCCCCCC	12	0.826	0.9	1.57	20.86	e2xrlA1, e2xrlA2	"""alpha arrays"", ""alpha bundles"""	101.1.1.354, 191.1.1.4	2-67, 68-208	1-66, 67-207	"""HTH"", ""-"""	"""HTH"", ""-"""	"""tri-helical"", ""Tetracyclin repressor-like, C-terminal domain"""	"""TetR_N"", ""TetR_C"""	1.10.10.60, 1.10.357.10	2-66, 67-207	1-65, 66-206	"""Mainly Alpha"", ""Mainly Alpha"""	"""Orthogonal Bundle"", ""Orthogonal Bundle"""	"""Arc Repressor Mutant, subunit A"", ""Tetracycline Repressor; domain 2"""	"""Homeodomain-like"", ""Tetracycline Repressor, domain 2"""	3-67, 68-208	2-66, 67-207	"""All alpha proteins"", ""All alpha proteins"""	"""DNA/RNA-binding 3-helical bundle"", ""Tetracyclin repressor-like, C-terminal domain"""	"""Homeodomain-like"", ""Tetracyclin repressor-like, C-terminal domain"""	"""-"", ""Tetracyclin repressor-like, C-terminal domain"""	Optimal • Dom. n°1	n/a	1-207	2-208	SRLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGARPDEKQYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLREALQIMDSDDGEQAFLHGLESLIRGFEVQLTALLQIV
1sul_B	2.0	-	-	195	P38424	ENGB_BACSU	B. subtilis	Probable GTP-binding protein EngB	True	False	False	False	False	35	22	44	KNLARTSSKPGKT	CCCCCCCCCCCCC	13	0.929	0.904	0.79	16.36	e1sulB1	"""a/b three-layered sandwiches"""	2004.1.1.258	1-195	1-195	"""P-loop domains-like"""	"""P-loop domains-related"""	"""P-loop containing nucleoside triphosphate hydrolases"""	"""MnmE_helical_2nd"""	3.40.50.300	1-195	1-195	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""P-loop containing nucleotide triphosphate hydrolases"""	1-195	1-195	"""Alpha and beta proteins (a/b)"""	"""P-loop containing nucleoside triphosphate hydrolases"""	"""P-loop containing nucleoside triphosphate hydrolases"""	"""G proteins"""	Optimal • Dom. n°1	n/a	1-195	1-195	MKVTKSEIVISAVKPEQYPEGGLPEIALAGRSNVGKSSFINSLINRKNLARTSSKPGKTQTLNFYIINDELHFVDVPGYGFAKVSKSEREAWGRMIETYITTREELKAVVQIVDLRHAPSNDDVQMYEFLKYYGIPVIVIATKADKIPKGKWDKHAKVVRQTLNIDPEDELILFSSETKKGKDEAWGAIKKMINR
4iwb_A	1.75	-	-	165	O67803	FLAA_AQUAE	A. aeolicus	Flagellin	True	False	False	False	False	79	0	21	GAEAYFQNQ	CCCCCCCCC	9	0.944	0.932	0.72	16.37	e4iwbA1	"""alpha bundles"""	601.13.1.3	2-166	1-165	"""Four-helical up-and-down bundle"""	"""-"""	"""Flagellar export chaperone FliS"""	"""FliS"""	1.20.120.340	2-166	1-165	"""Mainly Alpha"""	"""Up-down Bundle"""	"""Four Helix Bundle (Hemerythrin (Met), subunit A)"""	"""Flagellar protein FliS"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-165	2-166	GRNVDFAKEMTEFTKYQIRMQSGVAMLAQANALPQLVLQLLRGAEAYFQNQVETATPLEQIILLYDKAIECLERAIEIYDQVNELEKRKEFVENIDRVYDIISALKSFLDHEKGKEIAKNLDTIYTIILNTLVKVDKTKEELQKILEILKDLREAWEEVKKKVHH
3gea_A	1.699	-	-	274	P14191	FAEG3_ECOLX	E. coli	K88 fimbrial protein AD	True	True	True	False	False	8	41	51	TPVTSGVD	CCCCCCCC	8	0.948	0.94	0.76	20.19	e3geaA1	"""beta sandwiches"""	11.1.5.23	1-274	1-4,11-253,258-274	"""Immunoglobulin-like beta-sandwich"""	"""Immunoglobulin-related"""	"""Common fold of diphtheria toxin/transcription factors/cytochrome f"""	"""Fimbrial_K88"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-274	1-274	WMTGHHHHHHRQKWEWKVGTGLNGFGSVLNDLTNGGTKLTITVTGNKPILLGRTKEAFATPVTSGVDGIPHIAFTDYEGASVELRNPDGETEKGLAYFVLPMKNAEGTKVGSVKVNASYAGALGRGGVTSADGELMSLFAEGSHAIFYGGLPTNVKNSELKGGSAAAARTELFGSLSKNDILGQIQRVNANITSLVNVPGSFNENMAYTDGSVVSVAYALGIANGQTIEATFNQAVTTSTQWSAPLNVAITYYDNKQMTGDFNGSVDIGGSITA
5ap9_A	1.8	-	-	269	O59952	LIP_THELA	T. lanuginosus	Lipase	True	True	False	False	False	30	24	46	GKNNDAPAGTN	HHHCCCCCCCE	11	0.952	0.949	0.7	17.39	e5ap9A1	"""a/b three-layered sandwiches"""	7579.1.1.13	1-269	1-269	"""-"""	"""-"""	"""alpha/beta-Hydrolases"""	"""Lipase_3"""	3.40.50.1820	1-269	1-269	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""alpha/beta hydrolase"""	1-269	1-269	"""Alpha and beta proteins (a/b)"""	"""alpha/beta-Hydrolases"""	"""alpha/beta-Hydrolases"""	"""Fungal lipases"""	Optimal • Dom. n°1	n/a	1-269	1-269	EVSQDLFNQFNLFAQYSAAAYCGKNNDAPAGTNITCTGNACPEVEKADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSCENWIGNLNFDLKEINDICSGCRGHDGFTSSWRSVADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGNGYDIDVFSYGAPRVGNRAFAEFLTVQTGGTLYRITHTNDIVPRLPPREFGYSHSSPEYWIKSGTLVPVTRNDIVKIEGIDATGGNNQPNIPDCPAHLWYFGLIGTCL
6y8q_A	1.83	-	-	195	Q8DZ36	Q8DZ36_STRA5	S. agalactiae serotype V	Abortive infection protein AbiGI	True	True	False	False	False	45	18	36	RGYRFNTPPAN	CCCCCCCCCCC	11	0.767	0.732	1.32	20.06	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-55, 56-195	1-55, 56-195	SKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYLQQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERIICDFVIHREKIDSELFVKTLQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI
1fpo_A	1.8	-	-	171	P0A6L9	HSCB_ECOLI	E. coli	Co-chaperone protein HscB	True	False	False	False	False	75	0	25	YHPDKFASGSQAEQ	CCHHHHCCCCHHHH	14	0.862	0.58	1.37	20.62	e1fpoA2, e1fpoA1	"""alpha bundles"", ""alpha bundles"""	622.1.1.2, 650.1.1.1	77-171, 1-76	77-171, 1-76	"""YvfG-like"", ""-"""	"""-"", ""-"""	"""HSC20 (HSCB), C-terminal oligomerisation domain"", ""Chaperone J-domain"""	"""HSCB_C"", ""DnaJ"""	1.10.287.110, 1.20.1280.20	1-79, 80-171	1-79, 80-171	"""Mainly Alpha"", ""Mainly Alpha"""	"""Orthogonal Bundle"", ""Up-down Bundle"""	"""Helix Hairpins"", ""Monooxygenase"""	"""DnaJ domain"", ""HscB, C-terminal domain"""	1-76, 77-171	1-76, 77-171	"""All alpha proteins"", ""All alpha proteins"""	"""Long alpha-hairpin"", ""Open three-helical up-and-down bundle"""	"""Chaperone J-domain"", ""HSC20 (HSCB), C-terminal oligomerisation domain"""	"""Chaperone J-domain"", ""HSC20 (HSCB), C-terminal oligomerisation domain"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-84, 85-171	1-84, 85-171	MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTCRKLRFLDKLRSSAEQLEEKLLDF
3kro_D	1.95	-	-	295	Q9SBR3	Q9SBR3_MENPI	M. piperita	Geranyl diphosphate synthase large subunit	True	True	True	False	False	72	2	27	KSSKELGKTAGKDLVADK	CCHHHHCCCCCHHHHCCC	18	0.879	0.783	1.1	19.09	e3kroD1	"""alpha bundles"""	141.1.1.11	1-295	1-295	"""-"""	"""-"""	"""Terpenoid synthases"""	"""polyprenyl_synt"""	1.10.600.10	1-295	1-295	"""Mainly Alpha"""	"""Orthogonal Bundle"""	"""Farnesyl Diphosphate Synthase"""	"""Farnesyl Diphosphate Synthase"""	2-295	2-295	"""All alpha proteins"""	"""Terpenoid synthases"""	"""Terpenoid synthases"""	"""-"""	Optimal • Dom. n°1	n/a	1-295	1-295	MFDFDGYMLRKAKSVNKALEAAVQMKEPLKIHESMRYSLLAGGKRVRPMLCIAACELVGGDESTAMPAACAVEMIHTMSLMHDDLPCMDNDDLRRGKPTNHMAFGESVAVLAGDALLSFAFEHVAAATKGAPPERIVRVLGELAVSIGSEGLVAGQVVDVCSEGMAEVGLDHLEFIHHHKTAALLQGSVVLGAILGGGKEEEVAKLRKFANCIGLLFQVVDDILDVTKSSKELGKTAGKDLVADKTTYPKLIGVEKSKEFADRLNREAQEQLLHFHPHRAAPLIALANYIAYRDN
4pid_A	1.59	-	-	204	P03252	PRO_ADE02	H. adenovirus C serotype 2	Protease	True	True	True	False	False	41	14	45	IASSPDRC	HHHCCCCC	8	0.95	0.926	0.76	16.55	e4pidA1	"""a+b complex topology"""	219.1.1.33	1-204	1-204	"""Cysteine proteinases-like"""	"""-"""	"""Cysteine proteinases"""	"""Peptidase_C5"""	3.40.395.10	1-204	1-204	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Adenoviral Proteinase; Chain"""	"""Adenoviral Proteinase; Chain A"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-204	1-204	MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRETGGVHWMAFAWNPRSKTCYLFEPFGFSDQRLKQVYQFEYESLLRRSAIASSPDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLITGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCHLKNM
2hlq_A	1.45	-	-	100	Q13873	BMPR2_HUMAN	H. sapiens	Bone morphogenetic protein receptor type-2	False	False	False	False	True	6	36	58	QQDLGIGESRISHE	HHHHCCCHHHEECC	14	0.749	0.685	1.57	13.94	e2hlqA1	"""few secondary structure elements"""	382.1.1.1	32-131	1-100	"""-"""	"""-"""	"""Snake toxin-like"""	"""Activin_recp"""	2.10.60.10	32-131	1-100	"""Mainly Beta"""	"""Ribbon"""	"""CD59"""	"""CD59"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-100	32-131	ALCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENF
2y8w_A	1.8	-	-	215	Q53WG9	CAS6_THET8	T. thermophilus	CRISPR-associated endoribonuclease Cse3	True	False	False	False	False	21	36	43	VRRKKDGEEAGKLL	EEECCCCCCCCEEE	14	0.909	0.89	1.06	18.04	e2y8wA2, e2y8wA1	"""a+b two layers"", ""a+b two layers"""	304.51.1.56, 304.51.1.57	88-211, -3-87	92-215, 1-91	"""Alpha-beta plaits"", ""Alpha-beta plaits"""	"""-"", ""-"""	"""CRISPR transcript (pre-crRNA) processing endoribonuclease-related"", ""CRISPR transcript (pre-crRNA) processing endoribonuclease-related"""	"""CRISPR_assoc_C"", ""CRISPR_assoc_N"""	3.30.70.1200, 3.30.70.1210	-3-87, 88-211	1-91, 92-215	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""2-Layer Sandwich"""	"""Alpha-Beta Plaits"", ""Alpha-Beta Plaits"""	"""Crispr-associated protein; domain 1"", ""Crispr-associated protein; domain 2"""	88-211, 1-87	92-215, 5-91	"""Alpha and beta proteins (a+b)"", ""Alpha and beta proteins (a+b)"""	"""Ferredoxin-like"", ""Ferredoxin-like"""	"""Ferredoxin-like domains from CRISPR-associated proteins"", ""Ferredoxin-like domains from CRISPR-associated proteins"""	"""CRISPR-associated endoribonuclease Cse3-like"", ""-"""	Optimal • Dom. n°1	n/a	1-215	-3-211	GTGAMWLTKLVLNPASRAARRDLANPYEMHRTLSKAVSRALEEGRERLLWRLEPARGLEPPVVLVQTLTEPDWSVLDEGYAQVFPPKPFHPALKPGQRLRFRLRANPAKRLAATGKRVALKTPAEKVAWLERRLEEGGFRLLEGERGPWVQILQDTFLEVRRKKDGEEAGKLLQVQAVLFEGRLEVVDPERALATLRRGVGPGKALGLGLLSVAP
1yfq_A	1.1	-	-	342	P26449	BUB3_YEAST	S. cerevisiae	Cell cycle arrest protein BUB3	False	False	True	False	False	2	49	49	DDQGDDYNS	CCCCCCCCC	9	0.885	0.903	1.22	20.19	e1yfqA1	"""beta duplicates or obligate multimers"""	5.1.4.40	1-342	1-342	"""beta-propeller-like"""	"""beta-propeller"""	"""7-bladed"""	"""ANAPC4_WD40_9"""	2.130.10.10	1-342	1-342	"""Mainly Beta"""	"""7 Propeller"""	"""Methylamine Dehydrogenase; Chain H"""	"""YVTN repeat-like/Quinoprotein amine dehydrogenase"""	1-341	1-341	"""All beta proteins"""	"""7-bladed beta-propeller"""	"""WD40 repeat-like"""	"""Cell cycle arrest protein BUB3"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-56,190-342, 57-189	1-56,190-342, 57-189	MQIVQIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNFIDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEANLGICRICKYGDDKLIAASWDGLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCEDDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCHRLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIACSDNILCLATSDDTFKTNAAIDQTIELNASSIYIIFDYENP
6xq1_A	1.51	-	-	212	Q15109	RAGE_HUMAN	H. sapiens	Advanced glycosylation end product-specific receptor	True	True	True	False	False	3	46	51	GLPRHRALRTA	CCCCCCCEECC	11	0.784	0.601	1.59	25.33	e6xq1A1, e6xq1A2	"""beta sandwiches"", ""beta sandwiches"""	11.1.1.2545, 11.1.1.2545	20-118, 119-231	1-99, 100-212	"""Immunoglobulin-like beta-sandwich"", ""Immunoglobulin-like beta-sandwich"""	"""Immunoglobulin-related"", ""Immunoglobulin-related"""	"""Immunoglobulin/Fibronectin type III/E set domains/PapD-like"", ""Immunoglobulin/Fibronectin type III/E set domains/PapD-like"""	"""I-set_15"", ""I-set_15"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-99, 100-212	20-118, 119-231	GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWE
7emu_A	1.35	-	-	183	G3XD33	G3XD33_PSEAE	P. aeruginosa	Heme acquisition protein HasAp	False	True	False	False	False	30	38	33	VNHRPGQGV	CCCCCCCCC	9	0.903	0.852	1.01	16.0	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-183	1-183	MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQGVDGSNTGGFNPGPFDGSQYALKSTASDAAFIAGGDLHYTLFSNPSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLGLDSPIAQGRDGTVHKVVYGLMSGDSSALQGQIDALLKAVDPSLSINSTFDQLAAAGVAHATPA
1i6j_A	2.0	-	-	256	P03355	POL_MLVMS	M. murine leukemia virus	Gag-Pol polyprotein	True	False	False	False	False	33	23	43	KKPGTNDY	EHHHCCCE	8	0.899	0.929	1.05	20.79	e1i6jA1	"""a+b two layers"""	304.48.1.19	24-278	2-256	"""Alpha-beta plaits"""	"""Adenylyl and guanylyl cyclase catalytic domain-like"""	"""Adenylyl and guanylyl cyclase catalytic domain-like"""	"""RVT_1"""	3.10.10.10, 3.30.70.270	52-121,166-187, 25-50,125-158,188-273	30-99,144-165, 3-28,103-136,166-251	"""Alpha Beta"", ""Alpha Beta"""	"""Roll"", ""2-Layer Sandwich"""	"""HIV Type 1 Reverse Transcriptase; Chain A, domain 1"", ""Alpha-Beta Plaits"""	"""HIV Type 1 Reverse Transcriptase, subunit A, domain 1"", ""-"""	23-278	1-256	"""Multi-domain proteins (alpha and beta)"""	"""DNA/RNA polymerases"""	"""DNA/RNA polymerases"""	"""Reverse transcriptase"""	Optimal • Dom. n°1	n/a	1-256	23-278	MTWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
5e5q_A	1.6	-	-	63	Q948Z4	SNAK1_SOLTU	S. tuberosum	Snakin-1	False	False	False	False	True	52	3	44	SNFCDSKCKLRCSKA	CHHHHHHHHHHCCCC	15	0.835	0.756	0.75	10.97	e5e5qA1	"""few secondary structure elements"""	397.8.1.1	1-63	1-63	"""Toxic hairpin"""	"""-"""	"""GASA/snakin"""	"""GASA"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-63	1-63	GSNFCDSKCKLRCSKAGLADRCLKYCGICCEECKCVPSGTYGNKHECPCYRDKKNSKGKSKCP
7vwk_A	2.0	-	-	260	L8PIV2	NaN	S. viridochromogenes Tue57	Antibiotic	True	False	False	False	False	16	37	47	DPGLVSRRLAEVGVP	CHHHHHHHHHHHCCC	15	0.919	0.891	1.02	18.69	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-260	915-1174	DSHTLLGTPGGVAGSDLRLWHSTLDDDSRPYPGSHALNGVEIVPAAVLAVTFLAAGAEGEERRALQDMTMTHPVLTAGQRQIQVVREGEVVRLASRTVADAADPNPAWLVHAEARTAAPDLAGLAARSLLDPGEHRLEPADPGLVSRRLAEVGVPSTGFDWSVERLSAGLGVLHAQVLSPDASSWAPLLDAVMSIAPAAFVGLPQLRMVVHVDEITVDGTPPEAATVEVALDPRVADTVHALVTDGEGRPVASLRGLRYP
3vzb_A	2.0	-	-	360	Q9NYA1	SPHK1_HUMAN	H. sapiens	Sphingosine kinase 1	True	True	True	False	False	30	30	39	VGSKTPASPVVV	CCCCCCCCCCCC	12	0.935	0.875	0.88	20.47	e3vzbA1, e3vzbA2	"""beta sandwiches"", ""a/b three-layered sandwiches"""	4004.1.1.3, 2007.1.4.1	146-364, 5-145	142-360, 1-141	"""-"", ""Flavodoxin-like"""	"""-"", ""Class I glutamine amidotransferase-like"""	"""NAD kinase beta sandwich domain-like"", ""Phosphofructokinase N-terminal domain"""	"""KOG1116"", ""DAGK_cat"""	2.60.200.40, 3.40.50.10330	151-364, 5-150	147-360, 1-146	"""Mainly Beta"", ""Alpha Beta"""	"""Sandwich"", ""3-Layer(aba) Sandwich"""	"""Tumour Suppressor Smad4"", ""Rossmann fold"""	"""-"", ""Probable inorganic polyphosphate/atp-NAD kinase; domain 1"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-360	5-364	AMGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG
5x1u_B	1.8	-	-	208	Q5WZ95	Q5WZ95_LEGPL	L. pneumophila	IcmP protein	True	False	False	False	False	61	2	37	KDDALLDNPVPGEEMT	CCCCCCCCCCCCCCCC	16	0.885	0.875	1.28	19.42	e5x1uB1	"""alpha complex topology"""	1165.1.1.1	162-369	1-208	"""-"""	"""-"""	"""DotM cytosolic domain"""	"""UNK_F_TYPE"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-208	162-369	ALTPMEFARKYNLLRKDDALLDNPVPGEEMTAGIRRGDAKRVFTMQLGPYWDGFERCSPQAYALSAVFMARMNRDRDAANNILKVLDKTFVDGKPDFSVARPVMKKYQNSELVQEVVAKHAYVLTVIASLLEAAREDGVVPSSEFLWLKPVDRRLWYMLNCVGRQTPYSEVAGPFAHWKAEKEMGRRSLVPMIDEAIRALEIAVKEVR
3cc1_A	2.0	-	-	433	Q9KBQ5	Q9KBQ5_HALH5	H. halodurans	Alpha-galactosidase	True	True	True	False	False	29	24	47	YAHHFKTNANM	CCCCCCCCCHH	11	0.917	0.927	1.09	23.16	e3cc1A2, e3cc1A3	"""beta sandwiches"", ""a/b barrels"""	12.1.1.47, 2002.1.1.222	344-432, 0-137,158-343	345-433, 1-138,159-344	"""Glycosyl hydrolase domain-like"", ""TIM beta/alpha-barrel"""	"""-"", ""-"""	"""Glycosyl hydrolase domain"", ""TIM barrels"""	"""Melibiase_2_C_2"", ""Glyco_hydro_31_N"""	2.60.40.1180, 3.20.20.70	345-432, 0-344	346-433, 1-345	"""Mainly Beta"", ""Alpha Beta"""	"""Sandwich"", ""Alpha-Beta Barrel"""	"""Immunoglobulin-like"", ""TIM Barrel"""	"""Golgi alpha-mannosidase II"", ""Aldolase class I"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-53,219-433, 54-218	0-52,218-432, 53-217	GMEVNRLSALTPPMGWNSWDCYGASVTEEEVLGNAEYMANHLKKYGWEYIVVDIQWYEPTANSSAYNPFAPLCMDEYGRLLPATNRFPSAKNGAGFKPLSDAIHDLGLKFGIHIMRGIPRQAVYENSPVLGSTKTAREIAHTNSICPWNTDMYGVDPTKEGAQSYYNSLFELYAQWGVDFVKVDDIAASRLYDTHLEEIKMIQRAIQACGRPMVLSLSPGPAPIKYAHHFKTNANMWRITDDFWDDWSLLYQMFERCEVWEKHIGTGHWPDCGMLPLGHIGIRSVDGPGGDRWTRFTKDEQLTMMNLWAICHSPLMFGGELRDNDEWTLSLLTNEGILSINQKSVLNRFVYREEDKVAWAANGRNGEAYVALFNLHDQQKTLQFRLDMVGIMETVQLFNVWDRSFLQSLAPSESFQIELKPHQSMMLKLSPDR
3vpd_A	1.95	-	-	281	Q5SH23	LYSX_THET8	T. thermophilus	Alpha-aminoadipate--LysW ligase LysX	True	True	False	False	False	40	26	33	RSAHWITNTARGG	ECCCCCCCHHHCC	13	0.831	0.775	1.13	20.42	e3vpdA1, e3vpdA2	"""a+b complex topology"", ""a/b three-layered sandwiches"""	206.1.3.22, 2003.1.10.17	89-281, 1-88	89-281, 1-88	"""-"", ""Rossmann-like"""	"""Protein kinase/SAICAR synthase/ATP-grasp"", ""Rossmann-related"""	"""ATP-grasp"", ""PreATP-grasp domain"""	"""RimK"", ""LysX_arch"""	3.30.470.20, 3.30.1490.20, 3.40.50.20	173-281, 104-172, 1-103	173-281, 104-172, 1-103	"""Alpha Beta"", ""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""D-amino Acid Aminotransferase; Chain A, domain 1"", ""Dna Ligase; domain 1"", ""Rossmann fold"""	"""ATP-grasp fold, B domain"", ""ATP-grasp fold, A domain"", ""-"""	1-88, 89-281	1-88, 89-281	"""Alpha and beta proteins (a/b)"", ""Alpha and beta proteins (a+b)"""	"""PreATP-grasp domain"", ""ATP-grasp"""	"""PreATP-grasp domain"", ""Glutathione synthetase ATP-binding domain-like"""	"""-"", ""Lysine biosynthesis enzyme LysX ATP-binding domain"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-104,172-281, 105-171	1-104,172-281, 105-171	MLAILYDRIRPDERMLFERAEALGLPYKKVYVPALPMVLGERPEALEGVTVALERCVSQSRGLAAARYLTALGIPVVNRPEVIEACGDKWATSVALAKAGLPQPKTALATDREEALRLMEAFGYPVVLKPVIGSWGRLLAKVTDRAAAEALLEHKEVLGGFQHQLFYIQEYVEKPGRDIRVFVVGERAIAAIYRRSAHWITNTARGGQAENCPLTEEIARLSVGAAEAVGGGVVAVDLFESERGLLVNEVNHTMEFKNSVHTTGVDIPGEILRYAWEVARG
4nq6_A	1.8	-	-	222	P04190	BLA2_BACCE	B. cereus	Metallo-beta-lactamase type 2	False	True	True	False	False	26	31	43	GSFNGEAV	EECCCCEE	8	0.937	0.909	0.8	16.64	e4nq6A1	"""a+b four layers"""	247.1.1.37	6-227	1-222	"""-"""	"""-"""	"""Metallo-hydrolase/oxidoreductase"""	"""Lactamase_B"""	3.60.15.10	6-227	1-222	"""Alpha Beta"""	"""4-Layer Sandwich"""	"""Metallo-beta-lactamase; Chain A"""	"""Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"""	6-227	1-222	"""Alpha and beta proteins (a+b)"""	"""Metallo-hydrolase/oxidoreductase"""	"""Metallo-hydrolase/oxidoreductase"""	"""Zn metallo-beta-lactamase"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-122, 123-222	6-127, 128-227	KTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK
1se4_A	1.9	-	-	239	P01552	ETXB_STAAU	S. aureus	Enterotoxin type B	False	False	False	False	True	17	38	45	KKTNDINSHQTD	CCCCCCCCCCCC	12	0.897	0.894	1.13	18.87	e1se4A1, e1se4A2	"""beta barrels"", ""a+b two layers"""	2.2.1.8, 221.1.1.33	1-121, 122-238	1-121, 122-238	"""OB-fold"", ""beta-Grasp"""	"""-"", ""Ubiquitin-related"""	"""Bacterial enterotoxins"", ""Ubiquitin-like"""	"""Stap_Strp_toxin"", ""Stap_Strp_tox_C"""	2.40.50.110, 3.10.20.120	32-121, 2-31,128-231	32-121, 2-31,128-231	"""Mainly Beta"", ""Alpha Beta"""	"""Beta Barrel"", ""Roll"""	"""OB fold (Dihydrolipoamide Acetyltransferase, E2P)"", ""Ubiquitin-like (UB roll)"""	"""-"", ""-"""	1-121, 122-239	1-121, 122-239	"""All beta proteins"", ""Alpha and beta proteins (a+b)"""	"""OB-fold"", ""beta-Grasp (ubiquitin-like)"""	"""Bacterial enterotoxins"", ""Superantigen toxins, C-terminal domain"""	"""Superantigen toxins, N-terminal domain"", ""Superantigen toxins, C-terminal domain"""	Optimal • Dom. n°1	n/a	1-239	1-239	ESQPDPKPDELHKSSKFTGLMENMKVLYDDNHVSAINVKSIDQFLYFDLIYSIKDTKLGNYDNVRVEFKNKDLADKYKDKYVDVFGANYYYQCYFSKKTNDINSHQTDKRKTCMYGGVTEHNGNQLDKYRSITVRVFEDGKNLLSFDVQTNKKKVTAQELDYLTRHYLVKNKKLYEFNNSPYETGYIKFIENENSFWYDMMPAPGDKFDQSKYLMMYNDNKMVDSKDVKIEVYLTTKKK
4bym_A	1.598	-	-	342	Q939Q9	Q939Q9_PAULE	P. lemoignei	Lipase	True	False	True	False	False	28	17	56	QADYDWADGMPY	CCCCCHHHCCCC	12	0.973	0.968	0.6	18.58	e4bymA1	"""a/b three-layered sandwiches"""	7579.1.1.12	1-342	1-342	"""-"""	"""-"""	"""alpha/beta-Hydrolases"""	"""Lipase_2"""	3.40.50.1820	1-342	1-342	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""alpha/beta hydrolase"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-342	1-342	LTCGTNSGFVCKGTQTQYAGGFAPGVGYGGFGGGSCTATKTPVIFIHGNGDNAISFDMPPGNVSGYGTPARSVYAELKARGYNDCEIFGVTYLSSSEQGSAQYNEHSSTKYAIIKTFIDKVKAYTGKSQVDIVAHSMGVSMSLATLQYYNNWTSVRKFINLAGGIRGLYSCYYTGYANAAAPTCGSQNYYNSYTFGFFPEGWYYGVWVSNPWTGSGSTNSMRDMPAKRTAVSFYTLSAGFKDQVGCATASFWAGCDSAAKFASTTSNVKAQINVGAGSNATQADYDWADGMPYNAGGGDTTNGVGHFRTKTNTGAIIQRMLLTTCTGLDCAAEYTTGPKAAY
3hhp_A	1.45	-	-	312	P61889	MDH_ECOLI	E. coli	Malate dehydrogenase	True	False	False	False	False	47	18	35	VARKPGMDRSD	CCCCCCCCHHH	11	0.928	0.942	0.91	19.1	e3hhpA1, e3hhpA2	"""a+b complex topology"", ""a/b three-layered sandwiches"""	279.1.1.2, 2003.1.1.40	146-312, 1-145	146-312, 1-145	"""-"", ""Rossmann-like"""	"""-"", ""Rossmann-related"""	"""LDH C-terminal domain-like"", ""NAD(P)-binding Rossmann-fold domains"""	"""Ldh_1_C_1"", ""Ldh_1_N"""	3.40.50.720, 3.90.110.10	1-146, 147-312	1-146, 147-312	"""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""Alpha-Beta Complex"""	"""Rossmann fold"", ""L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2"""	"""NAD(P)-binding Rossmann-like Domain"", ""Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"""	1-145, 146-312	1-145, 146-312	"""Alpha and beta proteins (a/b)"", ""Alpha and beta proteins (a+b)"""	"""NAD(P)-binding Rossmann-fold domains"", ""LDH C-terminal domain-like"""	"""NAD(P)-binding Rossmann-fold domains"", ""LDH C-terminal domain-like"""	"""-"", ""Lactate & malate dehydrogenases, C-terminal domain"""	Optimal • Dom. n°1	n/a	1-312	1-312	MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
3h8k_A	1.8	-	-	164	P60604	UB2G2_HUMAN	H. sapiens	Ubiquitin-conjugating enzyme E2 G2	True	False	False	False	False	34	16	49	GDDPMGYESS	CCCCCCCCCC	10	0.901	0.85	0.86	16.47	e3h8kA1	"""a+b two layers"""	216.1.1.7	2-165	1-164	"""UBC-like"""	"""-"""	"""UBC-like"""	"""UQ_con"""	3.10.110.10	2-165	1-164	"""Alpha Beta"""	"""Roll"""	"""Ubiquitin Conjugating Enzyme"""	"""Ubiquitin Conjugating Enzyme"""	2-165	1-164	"""Alpha and beta proteins (a+b)"""	"""UBC-like"""	"""UBC-like"""	"""UBC-related"""	Optimal • Dom. n°1	n/a	1-164	2-165	AGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL
1zah_A	1.8	-	-	363	P00883	ALDOA_RABIT	O. cuniculus	Fructose-bisphosphate aldolase A	True	False	False	False	False	45	14	41	SGQAGAAASESLFIS	CCCCCCCCCCCCCCC	15	0.912	0.888	1.0	20.34	e1zahA1	"""a/b barrels"""	2002.1.1.70	1-347	1-347	"""TIM beta/alpha-barrel"""	"""-"""	"""TIM barrels"""	"""Glycolytic"""	3.20.20.70	1-363	1-363	"""Alpha Beta"""	"""Alpha-Beta Barrel"""	"""TIM Barrel"""	"""Aldolase class I"""	1-363	1-363	"""Alpha and beta proteins (a/b)"""	"""TIM beta/alpha-barrel"""	"""Aldolase"""	"""Class I aldolase"""	Optimal • Dom. n°1	n/a	1-363	1-363	PHSHPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY
3r8r_A	1.9	-	-	212	P19669	TAL_BACSU	B. subtilis	Transaldolase	True	True	True	False	False	53	19	27	PSLVAKEANV	HHHHHCCCCC	10	0.841	0.88	2.07	17.69	e3r8rA1	"""a/b barrels"""	2002.1.1.183	1-212	1-212	"""TIM beta/alpha-barrel"""	"""-"""	"""TIM barrels"""	"""TAL_FSA"""	3.20.20.70	1-212	1-212	"""Alpha Beta"""	"""Alpha-Beta Barrel"""	"""TIM Barrel"""	"""Aldolase class I"""	1-212	1-212	"""Alpha and beta proteins (a/b)"""	"""TIM beta/alpha-barrel"""	"""Aldolase"""	"""-"""	Optimal • Dom. n°1	n/a	1-212	1-212	MLFFVDTANIDEIREANELGILAGVTTNPSLVAKEANVSFHDRLREITDVVKGSVSAEVISLKAEEMIEEGKELAKIAPNITVKIPMTSDGLKAVRALTDLGIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGHNGLDLISEVKQIFDIHGLDTQIIAASIRHPQHVTEAALRGAHIGTMPLKVIHALTKHPLTDKGIEQFLADWNK
4s3j_B	1.6	-	-	433	-	-	B. cereus	Hydrolase	True	True	False	False	False	35	23	42	SNQKGKFF	CCCCCCCC	8	0.945	0.944	0.87	23.15	e4s3jB2, e4s3jB3, e4s3jB4, e4s3jB1	"""alpha arrays"", ""alpha arrays"", ""a+b two layers"", ""a/b barrels"""	101.15.1.9, 101.15.1.9, 284.2.1.5, 2002.1.1.78	0-51, 52-100, 324-384, 101-323,384-432	1-52, 53-101, 325-385, 102-324,385-433	"""HTH"", ""HTH"", ""FKBP-like"", ""TIM beta/alpha-barrel"""	"""-"", ""-"", ""-"", ""-"""	"""LysM domain"", ""LysM domain"", ""Chitinase insertion domain"", ""TIM barrels"""	"""LysM"", ""LysM"", ""GH18_CFLE_spore_hydrolase"", ""Glyco_hydro_18"""	3.10.50.10, 3.20.20.80	324-383, 101-323,384-432	325-384, 102-324,385-433	"""Alpha Beta"", ""Alpha Beta"""	"""Roll"", ""Alpha-Beta Barrel"""	"""Chitinase A; domain 3"", ""TIM Barrel"""	"""-"", ""Glycosidases"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-139,282-433, 140-281	0-138,281-432, 139-280	FAIQIVTVRSGDSVYSLASKYGSTPDEIVKDNGLNPAETLVVGQALIVNTKGNNYYVQPGDSLYRISQTYNVPLASLAKVNNLSLKSILHVGQQLYVPKGTKRSVESIAYLQPSTIPIKESLVNATRAINPFLTYLAYFSFEAKRDGTLKEPTETAKIANIATQGQTIPMLVITNIENGNFSADLTSVILRDATIQNKFITNILQTAEKYGMRDIHFDFESVAPEDREAYNRFLRNVKIRLPSGYTLSTTLVPKTSSNQKGKFFEAHDYKAQGQIVDFVVIMTYDWGWQGGPPMAISPIGPVKEVLQYAKSQMPPQKIMMGQNLYGFDWKLPFKQGNPPAKAVSSVAAVALARKYNVPIRYDFTAQAPHFNYFDENGVQHEVWFEDARSIQSKFNLMKEQGIGGISYWKIGLPFPQNWRLLVENFTITKKGEN
4c5j_A	1.45	-	-	276	A0A0H3JTP0	A0A0H3JTP0_STAAM	S. aureus	Phosphomethylpyrimidine kinase	True	False	True	False	False	41	22	37	VCKGEDEVL	CEEECCEEC	9	0.93	0.922	0.85	17.8	e4c5jA1	"""a/b three-layered sandwiches"""	2003.6.1.4	1-276	1-276	"""Rossmann-like"""	"""-"""	"""Ribokinase-like"""	"""PfkB"""	3.40.1190.20	1-276	1-276	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""UDP-N-acetylmuramoyl-L-alanine"""	"""-"""	2-276	2-276	"""Alpha and beta proteins (a/b)"""	"""Ribokinase-like"""	"""Ribokinase-like"""	"""-"""	Optimal • Dom. n°1	n/a	1-276	1-276	GALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALTAIVTMDKDTWSHDVTPLPMDVFEKQLETALSIGPDAIKTGMLGTEEIIKRAGEVYEASNAQYFVVDPVMVCKGEDEVLNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLGKLNSIEDMKKAATIIFDKGAQHVIIKGGKALDQDKSYDLYYDGQTFYQLTTDMFQQSYNHGAGCTFAAATTAYLANGKSPKEAVISAKAFVASAIKNGWKMNDFVGPVDHGAYNRIEHIDVEVTEV
1i58_A	1.6	-	-	189	Q56310	CHEA_THEMA	T. maritima	Chemotaxis protein CheA	True	True	True	False	False	45	23	32	TKEKVSEVSGRG	HHHHHHHHHCCC	12	0.872	0.858	1.12	17.41	e1i58A1	"""a+b two layers"""	225.1.1.3	352-540	1-189	"""ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like"""	"""-"""	"""ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"""	"""HATPase_c"""	3.30.565.10	352-540	1-189	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""Heat Shock Protein 90"""	"""Histidine kinase-like ATPase, C-terminal domain"""	352-540	1-189	"""Alpha and beta proteins (a+b)"""	"""ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"""	"""ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"""	"""Histidine kinase"""	Optimal • Dom. n°1	n/a	1-189	352-540	GSHMVPISFVFNRFPRMVRDLAKKMNKEVNFIMRGEDTELDRTFVEEIGEPLLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRKAIEKGLIDESKAATLSDQEILNFLFVPGFSTKEKVSEVSGRGVGMDVVKNVVESLNGSISIESEKDKGTKVTIRLPLT
4kkx_A	1.77	-	-	268	P00929	TRPA_SALTY	S. typhimurium	Tryptophan synthase alpha chain	True	True	True	False	False	51	14	35	SRSGVTGAENRGALPLHH	CCCCCECCCCCCCCCCHH	18	0.935	0.937	0.79	17.69	e4kkxA1	"""a/b barrels"""	2002.1.1.184	1-268	1-268	"""TIM beta/alpha-barrel"""	"""-"""	"""TIM barrels"""	"""Trp_syntA"""	3.20.20.70	1-268	1-268	"""Alpha Beta"""	"""Alpha-Beta Barrel"""	"""TIM Barrel"""	"""Aldolase class I"""	1-268	1-268	"""Alpha and beta proteins (a/b)"""	"""TIM beta/alpha-barrel"""	"""Ribulose-phoshate binding barrel"""	"""Tryptophan biosynthesis enzymes"""	Optimal • Dom. n°1	n/a	1-268	1-268	MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQMLAELRSFVSAMKAASRA
2x26_A	1.75	-	-	308	P75853	SSUA_ECOLI	E. coli	Putative aliphatic sulfonates-binding protein	True	True	False	False	False	45	18	38	PTQLEGKQLEFRVPGNE	CCCCCCCCCCCCCCCCC	17	0.866	0.882	2.68	21.37	e2x26A1, e2x26A2	"""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"""	7523.1.1.10, 7523.1.1.100	107-212, 25-106,208-332	83-188, 1-82,184-308	"""-"", ""-"""	"""-"", ""-"""	"""Periplasmic binding protein-like II"", ""Periplasmic binding protein-like II"""	"""NMT1_2_1st_1"", ""PBP2_SsuA"""	3.40.190.10, 3.40.190.10	25-106,207-309, 107-206	1-82,183-285, 83-182	"""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""3-Layer(aba) Sandwich"""	"""D-Maltodextrin-Binding Protein; domain 2"", ""D-Maltodextrin-Binding Protein; domain 2"""	"""Periplasmic binding protein-like II"", ""Periplasmic binding protein-like II"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-82,183-308, 83-182	25-106,207-332, 107-206	SPEALRIGYQKGSIGMVLAKSHQLLEKRYPESKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVGVEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQPTYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPYAEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKPVNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQLEFRVPGNENLYFQ
1pqu_A	1.92	-	-	371	P44801	DHAS_HAEIN	H. influenzae	Aspartate-semialdehyde dehydrogenase	True	True	True	False	False	40	21	39	AGQKAPVFGGKDAGD	CCCECCCHHHCCCCE	15	0.903	0.904	1.25	22.87	e1pquA1, e1pquA2	"""a+b two layers"", ""a/b three-layered sandwiches"""	298.1.1.14, 2003.1.1.59	135-357, 1-133,358-371	135-357, 1-133,358-371	"""FwdE/GAPDH domain-like"", ""Rossmann-like"""	"""-"", ""Rossmann-related"""	"""Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"", ""NAD(P)-binding Rossmann-fold domains"""	"""Semialdhyde_dhC"", ""Semialdhyde_dh"""	3.30.360.10, 3.40.50.720	136-353, 1-135,354-371	136-353, 1-135,354-371	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""Dihydrodipicolinate Reductase; domain 2"", ""Rossmann fold"""	"""Dihydrodipicolinate Reductase; domain 2"", ""NAD(P)-binding Rossmann-like Domain"""	1-133,358-371, 134-357	1-133,358-371, 134-357	"""Alpha and beta proteins (a/b)"", ""Alpha and beta proteins (a+b)"""	"""NAD(P)-binding Rossmann-fold domains"", ""FwdE/GAPDH domain-like"""	"""NAD(P)-binding Rossmann-fold domains"", ""Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"""	"""Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain"", ""GAPDH-like"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-134,354-371, 135-353	1-134,354-371, 135-353	MKNVGFIGWRGMVGSVLMDRMSQENDFENLNPVFFTTSQAGQKAPVFGGKDAGDLKSAFDIEELKKLDIIVTCQGGDYTNEVYPKLKATGWDGYWVDAASALRMKDDAIIVLDPVNQHVISEGLKKGIKTFVGGNCTVSLMLMAIGGLFEKDLVEWISVATYQAASGAGAKNMRELLSQMGLLEQAVSSELKDPASSILDIERKVTAKMRADNFPTDNFGAALGGSLIPWIDKLLPETGQTKEEWKGYAETNKILGLSDNPIPVDGLCVRIGALRCNSQAFTIKLKKDLPLEEIEQIIASHNEWVKVIPNDKEITLRELTPAKVTGTLSVPVGRLRKLAMGPEYLAAFTVGDQLLWGAAEPVRRILKQLVA
5c2i_A	1.89	-	-	468	Q8YWM0	Q8YWM0_NOSS1	N. sp.	Alr1585 protein	True	True	False	False	False	33	19	47	LLTTDGHF	HCCCCCCH	8	0.967	0.965	0.74	22.54	e5c2iA1, e5c2iA2	"""a+b two layers"", ""a+b two layers"""	304.4.1.72, 304.4.1.108	2-191, 192-469	1-190, 191-468	"""Alpha-beta plaits"", ""Alpha-beta plaits"""	"""-"", ""-"""	"""Dimeric alpha+beta barrel"", ""Dimeric alpha+beta barrel"""	"""EfeB"", ""Dyp_perox_C"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-468	2-469	ALTEKDLKNLPEDGIDSENPGKYRNLLNDLQGNILKGHGRDHSVHLFLQFKPEQVEVVKQWIQSFAQTYITSAKKQADEAFKYRQKGVSGDVFANFFLSRHGYEYLEIEPFQIPGDKPFRMGMKNEEIRSSLGDPKIATWELGFQSEIHALVLIADDDIVDLLQIVNQITQKLRQIAEIVHREDGFILRNQAGQIIEHFGFVHGVSQPLFMKRDVVRERVNNCDFDKWDPKAPLDSILVEDPNGNTKDSYGSYLVYRKLEQNVKAFREDQRKLAQKLNIQENLAGALIVGRFADGTPVTLSDIPTYAVTPTNNFNYDGDLAATKCPFHSHTRKTNPRGDTARLLTTDGHFDEAFKEERGHRITRRAVSYGENNPSKEPVSGSGLLFLCFQSNIENQFNFMQSRWANPQNFVQVNTGPDPLIGQPSGTQKWPKKWGEPETEEYNFQLWINMKGGEYFFAPSISFLKTLA
3gqz_A	1.8	-	-	358	P00811	AMPC_ECOLI	E. coli	Beta-lactamase	True	True	False	False	False	37	23	40	VNPDSIINGSDNKIAL	CCCHHHHCCCCCCCCC	16	0.937	0.915	0.86	20.05	e3gqzA4, e3gqzA3	"""alpha complex topology"", ""a+b three layers"""	4019.1.1.25, 223.3.1.22	61-224, 4-60,225-361	58-221, 1-57,222-358	"""-"", ""Profilin-like"""	"""-"", ""-"""	"""alpha-helical domain in beta-lactamase/transpeptidase-like proteins"", ""a+b domain in beta-lactamase/transpeptidase-like proteins"""	"""Beta-lactamase_1st"", ""Beta-lactamase_2nd"""	3.40.710.10	4-361	1-358	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Beta-lactamase"""	"""DD-peptidase/beta-lactamase superfamily"""	4-361	1-358	"""Multi-domain proteins (alpha and beta)"""	"""beta-lactamase/transpeptidase-like"""	"""beta-lactamase/transpeptidase-like"""	"""beta-Lactamase/D-ala carboxypeptidase"""	Optimal • Dom. n°1	n/a	1-358	4-361	APQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
2z3v_A	1.65	-	-	137	Q5SJV7	Q5SJV7_THET8	T. thermophilus	Universal stress protein family	False	True	False	False	False	47	20	34	VPDYLGEPFFEEAL	CCCCCCCCHHHHHH	14	0.893	0.842	0.96	15.69	e2z3vA1	"""a/b three-layered sandwiches"""	2005.1.1.145	2-136	2-136	"""HUP domain-like"""	"""-"""	"""HUP domains"""	"""Usp"""	3.40.50.620	1-137	1-137	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""HUPs"""	1-137	1-137	"""Alpha and beta proteins (a/b)"""	"""Adenine nucleotide alpha hydrolase-like"""	"""Adenine nucleotide alpha hydrolases-like"""	"""Universal stress protein-like"""	Optimal • Dom. n°1	n/a	1-137	1-137	MFKTILLAYDGSEHARRAAEVAKAEAEAHGARLIVVHAYEPVPDYLGEPFFEEALRRRLERAEGVLEEARALTGVPKEDALLLEGVPAEAILQAARAEKADLIVMGTRGLGALGSLFLGSQSQRVVAEAPCPVLLVR
5ktn_A	1.34	-	-	304	O57767	NADA_PYRHO	P. horikoshii	Quinolinate synthase	False	True	True	False	False	45	16	39	REATCAMANMLK	CCCCCCCHHHCC	12	0.93	0.91	0.91	20.23	e5ktnA1, e5ktnA2, e5ktnA3	"""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"""	7588.1.1.1, 7588.1.1.1, 7588.1.1.1	-3-78,261-300, 172-260, 79-171	1-82,265-304, 176-264, 83-175	"""-"", ""-"", ""-"""	"""-"", ""-"", ""-"""	"""NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase"", ""NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase"", ""NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase"""	"""NadA"", ""NadA"", ""NadA"""	3.40.50.10800, 3.40.50.10800, 3.40.50.10800	84-170, 171-252, -3-77,259-281	88-174, 175-256, 1-81,263-285	"""Alpha Beta"", ""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""3-Layer(aba) Sandwich"", ""3-Layer(aba) Sandwich"""	"""Rossmann fold"", ""Rossmann fold"", ""Rossmann fold"""	"""NadA-like"", ""NadA-like"", ""NadA-like"""	1-300	5-304	"""Alpha and beta proteins (a/b)"""	"""NadA-like"""	"""NadA-like"""	"""NadA-like"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	***, ***, ***	1-86,260-304, 87-173, 174-259	-3-82,256-300, 83-169, 170-255	GSFTMDLVEEILRLKEERNAIILAHNYQLPEVQDIADFIGDSLELARRATRVDADVIVFAGVDFMAETAKILNPDKVVLIPSREATCAMANMLKVEHILEAKRKYPNAPVVLYVNSTAEAKAYADVTVTSANAVEVVKKLDSDVVIFGPDKNLAHYVAKMTGKKIIPVPSKGHCYVHQKFTLDDVERAKKLHPNAKLMIHPECIPEVQEKADIIASTGGMIKRACEWDEWVVFTEREMVYRLRKLYPQKKFYPAREDAFCIGMKAITLKNIYESLKDMKYKVEVPEEIARKARKAIERMLEMSK
6h5c_A	1.14	-	-	252	P24670	AROD_SALTI	S. typhi	3-dehydroquinate dehydratase	True	True	False	False	False	45	19	36	KQASAPGQ	CCCCCCCC	8	0.953	0.932	0.78	17.49	e6h5cA1	"""a/b barrels"""	2002.1.1.40	1-252	1-252	"""TIM beta/alpha-barrel"""	"""-"""	"""TIM barrels"""	"""DHquinase_I"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	1-252	1-252	"""Alpha and beta proteins (a/b)"""	"""TIM beta/alpha-barrel"""	"""Aldolase"""	"""Class I aldolase"""	Optimal • Dom. n°1	n/a	1-252	1-252	MKTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKQASAPGQIAVNDLRSVLMILHNA
5lrp_A	1.941	-	-	206	Q5S581	Q5S581_MOPEI	M. virus AN20410	Nucleoprotein	True	False	True	False	False	35	19	46	KKKRGGKE	ECCCCCEE	8	0.856	0.898	1.2	17.42	e5lrpA1	"""mixed a+b and a/b"""	2484.1.1.106	365-570	1-206	"""Ribonuclease H-like"""	"""-"""	"""Ribonuclease H-like"""	"""Arena_ncap_C"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-206	365-570	GLTYSQTMELKDSMLQLDPNAKTWIDIEGRPEDPVEIAIYQPNNGQYIHFYREPTDIKQFKQDSKHSHGIDIQDLFSVQPGLTSAVIESLPKNMVLSCQGADDIRKLLDSQNRRDIKLIDVSMQKDDARKFEDKIWDEYKHLCRMHTGIVTQKKKRGGKEEVTPHCALLDCLMFEAAVIGSPQIPTPRPVLSRDLVFRTGPPRVVL
5nzb_A	1.695	-	-	132	A4K9Z8	PROF2_BETPN	B. pendula	Profilin-2	False	False	False	False	True	32	33	36	CDIDGQGQQ	CCCHHHHCC	9	0.813	0.719	1.32	14.28	e5nzbA1	"""a+b three layers"""	223.2.1.8	2-133	1-132	"""Profilin-like"""	"""-"""	"""profilin-like"""	"""Profilin"""	3.30.450.30	2-133	1-132	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""Beta-Lactamase"""	"""Dynein light chain 2a, cytoplasmic"""	2-133	1-132	"""Alpha and beta proteins (a+b)"""	"""Profilin-like"""	"""Profilin (actin-binding protein)"""	"""Profilin (actin-binding protein)"""	Optimal • Dom. n°1	n/a	1-132	2-133	SWQTYVDEHLMCDIDGQGQQLAASAIVGHDGSVWAQSSSFPQFKPQEITGIMKDFEEPGHLAPTGLHLGGIKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLIDQGL
7riz_A	-	MODELLER	-	309	Q6N3R9	NaN	-	Unnamed protein	True	True	True	True	False	1	53	46	WFPSRGTMM	EEEECCEEE	9	0.899	0.887	0.95	18.51	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-309	1-309	MSNVRVLATDLAFPEGPVVMPDGSVVLVEIRAQQLTRVWPDGRKEVVAKVPGGPNGAALGPDGKMYICNNGGFGWFPSRGTMMPGAPAPHEYIGGSIQRVDLQSGEVETLFDKCGEHPLKGPNDLVFDKHGGLWFTDLGKRRARDMDVGAAYYIKPGMTEITEQVFGTLPLNGIGLSPDEATMYAAETPTGRLWAFDLSGPGEVKPRDVIYRGEKGKPICGLGGYQMFDSLAVEASGNVCVATLVSGCISVIAPDGTLVEQVPTGDRVTTNIAFGGPDLKTAYITLSGKGELIAMDWSRPGLPLNFLNK
7str_C	-	MODELLER	-	130	P0DTC9	NCAP_SARS2	S. acute respiratory syndrome coronavirus 2	Nucleoprotein	True	True	True	True	False	2	25	73	RRIRGGDGKMKDL	CEEECCCCCEEEC	13	0.839	0.797	1.44	15.31	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-130	44-173	SNMNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYA
5xtk_A	1.74	MODELLER	-	152	Q8ZC05	XGPT_YERPE	Y. pestis	Xanthine-guanine phosphoribosyltransferase	True	True	True	True	False	26	26	47	SSYDHDNQRDLK	EEEEECCEEEEE	12	0.794	0.789	2.4	16.14	e5xtkA1	"""a/b three-layered sandwiches"""	7573.1.1.1	2-151	2-151	"""-"""	"""-"""	"""PRTase-like"""	"""Pribosyltran"""	3.40.50.2020	2-151	2-151	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""-"""	1-152	1-152	"""Alpha and beta proteins (a/b)"""	"""PRTase-like"""	"""PRTase-like"""	"""Phosphoribosyltransferases (PRTases)"""	Optimal • Dom. n°1	n/a	1-152	1-152	MNEKYVVTWDMLQIHARKLAQRLLPAEQWKGIIAVSRGGLVPAGILARELGIRYVDTVCISSYDHDNQRDLKVLKRAEGDGEGFIVIDDLVDTGGTATAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMAVTFVAPLSGK
7qs1_A	1.93	MODELLER	-	187	Q96F44	TRI11_HUMAN	H. sapiens	E3 ubiquitin-protein ligase TRIM11	True	True	True	True	False	6	34	60	YNSSERALA	EEECCCCEE	9	0.86	0.848	1.48	16.61	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-187	275-461	SMGLVETLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGS
6y2x_A	1.77	MODELLER	-	235	Q86UW9	DTX2_HUMAN	H. sapiens	Probable E3 ubiquitin-protein ligase DTX2	True	True	True	True	False	20	22	58	HGIQGPEHPNPGKPFTA	CEECCCCCCCCCCEEEC	17	0.673	0.575	3.4	22.24	e6y2xA1, e6y2xA2	"""a+b two layers"", ""few secondary structure elements"""	3169.1.1.1, 376.1.1.20	478-622, 391-477	91-235, 4-90	"""-"", ""RING/U-box-like"""	"""-"", ""RING/U-box-like"""	"""Carboxyl terminal domain of human deltex 3-like"", ""RING/U-box"""	"""Deltex_C"", ""zf-RING_2"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-92, 93-235	388-479, 480-622	GSEPEPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ
6s81_C	1.784	MODELLER	-	401	Q8TZW1	METK_PYRFU	P. furiosus	S-adenosylmethionine synthase	True	True	True	True	False	37	28	35	VSVFNKARENP	HHHHHHHHHCC	11	0.92	0.942	0.98	23.56	e6s81C1	"""a+b two layers"""	327.17.1.1	2-401	2-401	"""Alpha-lytic protease prodomain-like"""	"""-"""	"""S-adenosylmethionine synthetase"""	"""AdoMet_Synthase"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-401	1-401	MARNIVVEEIVRTPVEMQQVELVERKGIGHPDSIADGIAEAVSRALCREYIRRYGVILHHNTDQVEVVGGRAYPRFGGGEVVKPIYILLSGRAVELVDQELFPVHEVAIKAAKNYLKNAIRHLDVENHVIIDSRIGQGSVDLVSVFNKARENPIPLANDTSFGVGYAPLSETERLVLETEKLLNSEKFKKEYPAVGEDIKVMGLRRGNEIDLTIAAAIVDSEVATPKEYLEVKDKIKEAVEELAKEITSRKVNIYVNTADDPERGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHMSMEAAAGKNPVSHVGKIYNILAMLIAEDIAKTLPVEEVYVRILSQIGKPIDQPLVASIQVIPKPGHSVKEFEKDAYSIADEWLANITKVQKMILEDKISVF
6tto_A	1.31	MODELLER	-	317	Q6EZB3	Q6EZB3_DATME	D. metel	Hyoscyamine 6 beta-hydroxylase	True	True	True	True	False	28	27	44	PSTTIGSG	ECCCEEEE	8	0.943	0.909	0.97	19.93	e6ttoA1	"""beta sandwiches"""	10.12.1.225	35-345	5-315	"""jelly-roll"""	"""-"""	"""Double-stranded beta-helix"""	"""DIOX_N"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-317	31-347	SNADVPIIDLQQDHLLIVQQITKACQDFGLFQVINHGVPEKLMVEAMEVYKEFFALPAEEKEKFQPKGEPAKFELPLEQKAKLYVEGERRCNEEFLYWKDTLAHGCYPLHEELLNSWPEKPPTYRDVIAKYSVEVRKLTMRILDYICEGLGLKLGYFDNELTQIQMLLANYYPSCPDPSTTIGSGGHYDGNLITLLQQDLVGLQQLIVKDDKWIAVEPIPTAFVVNLGLTLKVMSNEKFEGSIHRVVTHPIRNRISIGTLIGPDYSCTIEPIKELISQENPPLYKPYPYAEFAEIYLSDKSDYDAGVKPYKINQFPN
7jyv_A	1.51	MODELLER	-	278	A0A5H2UYS3	A0A5H2UYS3_HUMAN	H. sapiens	MHC class I antigen	True	True	True	True	False	26	39	35	PPKTHMTHHPISDHEATL	CCEEEEEEEECCCCEEEE	18	0.62	0.61	2.87	24.53	e7jyvA1, e7jyvA2	"""beta sandwiches"", ""a+b two layers"""	11.1.1.2544, 233.1.1.2	182-276, 1-181	182-276, 1-181	"""Immunoglobulin-like beta-sandwich"", ""-"""	"""Immunoglobulin-related"", ""-"""	"""Immunoglobulin/Fibronectin type III/E set domains/PapD-like"", ""MHC antigen-recognition domain"""	"""C1-set_2"", ""MHC_I"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-181, 182-278	1-181, 182-278	GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSS
6f77_A	1.794	MODELLER	-	400	Q02635	AAPAT_RHIME	R. meliloti	Aspartate/prephenate aminotransferase	True	True	True	True	False	48	14	38	SATIAVSQKARELKAKGRD	CHHHHHHHHHHHHHHCCCC	19	0.94	0.94	1.05	21.78	e6f77A1, e6f77A2	"""a+b two layers"", ""a/b three-layered sandwiches"""	3016.1.1.192, 7577.1.1.5	287-401, 2-286	286-400, 2-285	"""-"", ""-"""	"""-"", ""-"""	"""C-terminal domain in some PLP-dependent transferases"", ""PLP-dependent transferases"""	"""Aminotran_1_2_C_1"", ""Aminotran_1_2_N"""	3.40.640.10, 3.90.1150.10	63-287, 2-62,288-396	63-286, 2-62,287-395	"""Alpha Beta"", ""Alpha Beta"""	"""3-Layer(aba) Sandwich"", ""Alpha-Beta Complex"""	"""Aspartate Aminotransferase; domain 2"", ""Aspartate Aminotransferase, domain 1"""	"""Type I PLP-dependent aspartate aminotransferase-like (Major domain)"", ""Aspartate Aminotransferase, domain 1"""	1-401	1-400	"""Alpha and beta proteins (a/b)"""	"""PLP-dependent transferase-like"""	"""PLP-dependent transferases"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-42,112-231,296-400, 43-111,232-295	1-42,112-232,297-401, 43-111,233-296	MAFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDAIDRGETKYTPVSGIPELREAIAKKFKRENNLDYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYAMTGWRIGYAAGPLHLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQGRRDLVVSMLNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKVIETDEDFVSELLETEGVAVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR
1bzy_A	2.0	MODELLER	-	217	P00492	HPRT_HUMAN	H. sapiens	Hypoxanthine-guanine phosphoribosyltransferase	True	True	True	True	False	29	32	39	SYCNDQSTGDIKVIGGDD	EEECCEEEEEEEEEECHH	18	0.854	0.834	1.1	17.92	e1bzyA1	"""a/b three-layered sandwiches"""	7573.1.1.1	4-217	4-217	"""-"""	"""-"""	"""PRTase-like"""	"""Pribosyltran"""	3.40.50.2020	4-217	4-217	"""Alpha Beta"""	"""3-Layer(aba) Sandwich"""	"""Rossmann fold"""	"""-"""	1-217	1-217	"""Alpha and beta proteins (a/b)"""	"""PRTase-like"""	"""PRTase-like"""	"""Phosphoribosyltransferases (PRTases)"""	Optimal • Dom. n°1	n/a	1-217	1-217	ATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
3jva_A	1.7	MODELLER	-	354	Q834W6	HYEP_ENTFA	E. faecalis	Hydrophobic dipeptide epimerase	True	True	True	True	False	41	24	35	FTIALGTIES	EEECCEEEEE	10	0.901	0.897	0.91	20.59	e3jvaA1, e3jvaA2	"""a+b two layers"", ""a/b barrels"""	218.1.1.3, 2002.1.1.1056	1-124, 125-353	1-124, 125-353	"""Enolase-N/ribosomal protein"", ""TIM beta/alpha-barrel"""	"""-"", ""-"""	"""Enolase N-terminal domain-like"", ""TIM barrels"""	"""MR_MLE_N"", ""MR_MLE_C_1"""	3.20.20.120, 3.30.390.10	115-353, 1-114	115-353, 1-114	"""Alpha Beta"", ""Alpha Beta"""	"""Alpha-Beta Barrel"", ""2-Layer Sandwich"""	"""TIM Barrel"", ""Enolase-like; domain 1"""	"""Enolase-like C-terminal domain"", ""Enolase-like, N-terminal domain"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-131,263-354, 132-262	1-131,263-354, 132-262	MKIKQVHVRASKIKLKETFTIALGTIESADSAIVEIETEEGLVGYGEGGPGIFITGETLAGTLETIELFGQAIIGLNPFNIEKIHEVMDKISAFAPAAKAAIDIACYDLMGQKAQLPLYQLLGGYDNQVITDITLGIDEPNVMAQKAVEKVKLGFDTLKIKVGTGIEADIARVKAIREAVGFDIKLRLDANQAWTPKDAVKAIQALADYQIELVEQPVKRRDLEGLKYVTSQVNTTIMADESCFDAQDALELVKKGTVDVINIKLMKCGGIHEALKINQICETAGIECMIGCMAEETTIGITAAAHLAAAQKNITRADLDATFGLETAPVTGGVSLEAKPLLELGEAAGLGISH
7tbu_A	1.85	MODELLER	-	458	Q5AME2	ARO1_CANAL	C. albicans	Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase	True	True	True	True	False	31	22	46	EISKRGVSSYD	CCCCCEEECCC	11	0.872	0.871	1.78	23.98	e7tbuA2, e7tbuA1	"""a+b two layers"", ""a+b two layers"""	328.6.1.1, 328.6.1.1	409-637, 387-408,638-841	23-251, 1-22,252-455	"""IF3-like"", ""IF3-like"""	"""-"", ""-"""	"""EPT/RTPC-like"", ""EPT/RTPC-like"""	"""EPSP_synthase_N_1"", ""EPSP_synthase_N_1"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-30,250-458, 31-249	387-416,636-844, 417-635	TDEVLVHPFTNPPKENIIVPPGSKSISNRALILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGNLVTSGEELYLGNAGTASRFLTTVASLVGKSQASDDVILTGNARMQERPIGPLVDALRSNGSEIEYLNKQGSLPLKISAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEEYTYHIPKGTYKNPSEYVIESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDAKFAVDVLKPMGCKVEQTTTSTTVTGPPRGHLKPLPHVDMEPMTDAFLTASVVAAVAKGGSSTSITGIANQRVKECNRIEAMVTELAKFGVPANELPDGIEIHGIDIEDLKTPEISKRGVSSYDDHRVAMSFSLLAGLCKEPVLILERSTTGKTWPGWWDILHSKFKIELDGYE
5jca_L	1.5	MODELLER	-	474	Q8U195	SUDHA_PYRFU	P. furiosus	Sulfide dehydrogenase subunit alpha	True	True	True	True	False	39	19	41	GEPDESGR	EEECCCCC	8	0.879	0.907	1.24	24.23	e5jcaL3, e5jcaL1, e5jcaL2	"""alpha arrays"", ""a/b three-layered sandwiches"", ""a/b three-layered sandwiches"""	187.1.1.3, 2003.1.2.30, 2003.1.3.40	2-155, 249-417, 156-248,418-472	2-155, 249-417, 156-248,418-472	"""alpha-helical ferredoxin-like"", ""Rossmann-like"", ""Rossmann-like"""	"""-"", ""Rossmann-related"", ""Rossmann-related"""	"""alpha-helical ferredoxin"", ""FAD/NAD(P)-binding domain"", ""Nucleotide-binding domain"""	"""Fer4_20"", ""Pyr_redox_2_3"", ""Pyr_redox_2"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	****, ****, ****	1-142, 143-253,404-474, 254-403	1-142, 143-253,404-474, 254-403	MPRLIKDRVPTPERSVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLIYGIPEFRLPKEIVKKELENLRRLGVKIETNVLVGKTITFEELREEYDAIFIGTGAGTPRIYPWPGVNLNGIYSANEFLTRINLMKAYKFPEYDTPIKVGKRVAVIGGGNTAMDAARSALRLGAEVWILYRRTRKEMTAREEEIKHAEEEGVKFMFLVTPKRFIGDENGNLKAIELEKMKLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNKTFLETVPGLKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHQYLSKEK
3enb_A	1.85	MODELLER	-	222	Q6P2Q9	PRP8_HUMAN	H. sapiens	Pre-mRNA-processing-splicing factor 8	True	True	True	True	False	42	21	37	IHKTFEGNLTTK	EEECCCCCEEEE	12	0.814	0.768	1.3	19.05	e3enbA1	"""mixed a+b and a/b"""	2484.1.1.46	1771-1989	3-221	"""Ribonuclease H-like"""	"""-"""	"""Ribonuclease H-like"""	"""PRP8_domainIV"""	1.20.80.40, 3.30.420.230	1922-1989, 1771-1921	154-221, 3-153	"""Mainly Alpha"", ""Alpha Beta"""	"""Up-down Bundle"", ""2-Layer Sandwich"""	"""Acyl-CoA Binding Protein"", ""Nucleotidyltransferase; domain 5"""	"""-"", ""-"""	1771-1989	3-221	"""Alpha and beta proteins (a/b)"""	"""Ribonuclease H-like motif"""	"""Ribonuclease H-like"""	"""Prp8 beta-finger domain-like"""	Optimal • Dom. n°1	n/a	1-222	1769-1990	GELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILAD
3r5x_A	2.0	MODELLER	-	307	Q81Q29	DDL_BACAN	B. anthracis	D-alanine--D-alanine ligase	True	True	True	True	False	39	27	34	AAEFFDYNAKYDDAS	EEEEECCEEEEEEEE	15	0.885	0.899	1.38	21.49	e3r5xA1, e3r5xA2	"""a+b complex topology"", ""a/b three-layered sandwiches"""	206.1.3.1, 2003.1.10.4	95-303, -2-94	98-306, 1-97	"""-"", ""Rossmann-like"""	"""Protein kinase/SAICAR synthase/ATP-grasp"", ""Rossmann-related"""	"""ATP-grasp"", ""PreATP-grasp domain"""	"""ATP-grasp"", ""Dala_Dala_lig_N"""	3.30.470.20, 3.30.1490.20, 3.40.50.20	83-108,176-303, 109-175, -2-82	86-111,179-306, 112-178, 1-85	"""Alpha Beta"", ""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""D-amino Acid Aminotransferase; Chain A, domain 1"", ""Dna Ligase; domain 1"", ""Rossmann fold"""	"""ATP-grasp fold, B domain"", ""ATP-grasp fold, A domain"", ""-"""	1-93, 94-303	4-96, 97-306	"""Alpha and beta proteins (a/b)"", ""Alpha and beta proteins (a+b)"""	"""PreATP-grasp domain"", ""ATP-grasp"""	"""PreATP-grasp domain"", ""Glutathione synthetase ATP-binding domain-like"""	"""D-Alanine ligase N-terminal domain"", ""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-113,178-307, 114-177	-2-110,175-304, 111-174	SNAMRIGVIMGGVSSEKQVSIMTGNEMIANLDKNKYEIVPITLNEKMDLIEKAKDIDFALLALHGKYGEDGTVQGTLESLGIPYSGSNMLSSGICMDKNISKKILRYEGIETPDWIELTKMEDLNFDELDKLGFPLVVKPNSGGSSVGVKIVYDKDELISMLETVFEWDSEVVIEKYIKGEEITCSIFDGKQLPIISIRHAAEFFDYNAKYDDASTIEEVIELPAELKERVNKASLACYKALKCSVYARVDMMVKDGIPYVMEVNTLPGMTQASLLPKSADAAGIHYSKLLDMIIETSLRVRKEEGF
2oa9_A	1.5	MODELLER	-	249	Q8RNV5	Q8RNV5_KOCVA	K. varians	R.MvaI	True	True	True	True	False	30	35	36	YHSGKKKGKTHDH	CCCCCCCCCEEEC	13	0.851	0.665	1.44	22.19	e2oa9A1	"""a/b three-layered sandwiches"""	2008.1.1.35	-2-246	1-249	"""Restriction endonuclease-like"""	"""-"""	"""Restriction endonuclease-like"""	"""MvaI_BcnI"""	3.30.70.3570, 3.40.210.20	64-159,189-232, -2-63,160-188,233-246	67-162,192-235, 1-66,163-191,236-249	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""Alpha-Beta Plaits"", ""PvuII Endonuclease; Chain A"""	"""MvaI/BcnI restriction endonuclease, recognition domain"", ""MvaI/BcnI restriction endonuclease, catalytic domain"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-249	-2-246	MKSMSEYLNLLKEAIQNVVDGGWHETKRKGNTGIGKTFEDLLEKEEDNLDAPDFHDIEIKTHETAAKSLLTLFTKSPTNPRGANTMLRNRYGKKDEYGNNILHQTVSGNRKTNSNSYNYDFKIDIDWESQVVRLEVFDKQDIMIDNSVYWSFDSLQNQLDKKLKYIAVISAESKIENEKKYYKYNSANLFTDLTVQSLCRGIENGDIKVDIRIGAYHSGKKKGKTHDHGTAFRINMEKLLEYGEVKVIV
8dqj_D	-	MODELLER	-	276	A0A3G3IHP7	NaN	-	Unnamed protein	True	True	True	True	False	41	22	37	QEESDVYKE	EEEECCCEE	9	0.862	0.788	1.55	22.04	-	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-60,246-276, 61-245	0-59,245-275, 60-244	SGTVKYTDAQIQRLREYGNGTYEQKVFEDLASRDAAFSKEMSVASTDNEKKIKGMIANPSRHGLTQLMNDIADALVAEGFIEVRTPIFISKDALARMTITEDKPLFKQVFWIDEKRALRPMLAPNLYSVMRDLRDHTDGPVKIFEMGSCFRKESHSGMHLEEFTMLSLCDMGPRGDATEVLKNYISVVMKAAGLPDYDLVQEESDVYKETIDVEINGQEVCSAAVGPHYLDAAHDVHEPTSGAGFGLERLLTIREKYSTVKKGGASISYLNGAKIN
4mts_A	1.8	MODELLER	-	131	Q9I5L8	Q9I5L8_PSEAE	P. aeruginosa	Aldoketomutase	True	True	True	True	False	16	40	44	EAGLMQHGRS	EEEECCCCCC	10	0.756	0.705	1.47	15.83	e4mtsA2, e4mtsA1	"""a+b two layers"", ""a+b two layers"""	211.1.1.48, 211.1.1.59	65-129, 1-64	65-129, 1-64	"""-"", ""-"""	"""-"", ""-"""	"""Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"", ""Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"""	"""Glyoxalase_1"", ""Glyoxalase_6"""	3.10.180.10	1-129	1-129	"""Alpha Beta"""	"""Roll"""	"""2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1"""	"""2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"""	1-131	1-131	"""Alpha and beta proteins (a+b)"""	"""Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"""	"""Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"""	"""-"""	Optimal • Dom. n°1	n/a	1-131	1-131	MRILHSMLRVADLEAALEFYTRALDMRLLRRRDYPEGRFTLAFVGYQDERAAAALELTHNWDRDGYTQGDGYGHLAIEVEDAAVTCARARALGYRVTREAGLMQHGRSVIAFLEDPDGYKVELIQKGTQFD
5m1k_A	1.2	MODELLER	-	191	A0A1L4BKS3	TERL_BPG20	T. phage G20c	Terminase, large subunit	True	True	True	True	False	30	26	43	RTASGNQVMRAYGR	ECCCCCEEEEECCC	14	0.897	0.867	0.93	16.41	e5m1kA1	"""mixed a+b and a/b"""	2484.1.1.111	254-442	2-190	"""Ribonuclease H-like"""	"""-"""	"""Ribonuclease H-like"""	"""Terminase_6C"""	3.30.420.240	254-442	2-190	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""Nucleotidyltransferase; domain 5"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-191	253-443	GPAMNSVFSGLDMLILLPYERRGTRLVVEDYRPDHIYCIGADFGKNQDYSVFSVLDLDTGAIACLERMNGATWSDQVARLKALSEDYGHAYVVADTWGVGDAIAEELDAQGINYTPLPVKSSSVKEQLISNLALLMEKGQVAVPNDKTILDELRNFRYYRTASGNQVMRAYGRGHDDIVMSLALAYSQYEG
1q8r_A	1.899	MODELLER	-	120	P0AG74	RUSA_ECOLI	E. coli	Crossover junction endodeoxyribonuclease RusA	True	True	True	True	False	31	32	38	YRHNRGRTH	EEECCCCEE	9	0.869	0.9	0.89	14.99	e1q8rA1	"""a+b three layers"""	301.4.1.1	1-118	1-118	"""Bacillus chorismate mutase-like"""	"""-"""	"""Holliday junction resolvase RusA"""	"""RusA"""	3.30.1330.70	1-118	1-118	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""60s Ribosomal Protein L30; Chain"""	"""Holliday junction resolvase RusA"""	1-120	1-120	"""Alpha and beta proteins (a+b)"""	"""Bacillus chorismate mutase-like"""	"""Holliday junction resolvase RusA"""	"""Holliday junction resolvase RusA"""	Optimal • Dom. n°1	n/a	1-120	1-120	MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE
6yrs_A	1.7	MODELLER	-	269	-	-	s. construct	Hydrolase	True	True	True	True	False	44	17	39	TGGKLLRAGLPADWRIGD	CCCCCCHHHCCCCCEEEE	18	0.936	0.861	0.89	18.59	e6yrsA1, e6yrsA2	"""alpha complex topology"", ""a+b three layers"""	4019.1.1.72, 223.3.1.97	67-180, 28-66,181-294	42-155, 4-41,156-267	"""-"", ""Profilin-like"""	"""-"", ""-"""	"""alpha-helical domain in beta-lactamase/transpeptidase-like proteins"", ""a+b domain in beta-lactamase/transpeptidase-like proteins"""	"""Peptidase_S11_1st_1"", ""Beta-lactamase2"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-269	25-296	MAAQLSEQLAELEKRSGGRVGVIVLDTATGRRIAYRGDERFPMMSTFKALLAAAVLARVDAGKERLGRRITYSKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGPAALTAFLRSIGDEVTRLDRWEPELNEAAPGDERDTTMPAAMAATLRTLLLGDALSPASRQQLVDWLVANKTGGKLLRAGLPADWRIGDKSGAGEHGSRNIIAVIGPPGRAPIIVVIYLTESQVDADARDAVIAEVGRLVVEAFHHHHHH
6hzh_B	1.83	MODELLER	-	346	-	-	C. trachomatis	Peptide binding protein	True	True	True	True	False	33	22	46	DDENGVYTPTVM	EECCCEEEECCC	12	0.891	0.882	1.15	20.18	e6hzhB1, e6hzhB2	"""alpha complex topology"", ""a+b three layers"""	4019.1.1.73, 223.3.1.78	331-440, 265-330,441-622	55-164, 5-54,165-346	"""-"", ""Profilin-like"""	"""-"", ""-"""	"""alpha-helical domain in beta-lactamase/transpeptidase-like proteins"", ""a+b domain in beta-lactamase/transpeptidase-like proteins"""	"""Transpeptidase_1st_1"", ""Transpeptidase_2nd"""	-	-	-	"""-"""	"""-"""	"""-"""	"""-"""	268-622	8-346	"""Multi-domain proteins (alpha and beta)"""	"""beta-lactamase/transpeptidase-like"""	"""beta-lactamase/transpeptidase-like"""	"""-"""	Optimal • Dom. n°1	n/a	1-346	261-622	GPGYQDPLTINADLQRVAEESLNAAVKRVGGVWGSAAVLEIGTGRLLALAPGGTRSVSAIYEPGSVGKLVTLAAAIDQKKVTPTSTFTVSSTRDMPNGERISDDSPHETQDMTVAGIIAHSYNTGTVQIGDTVSDSVRYEYMQKFGWGAKTGITLPSEESGILRPHTEWGDRDHYTTMFGQGVAVTTIQLAQMVAVFGQKGVLIPPRIIDGYDDENGVYTPTVMGESRQVVSEDTAQTVLNIMQGATQPGGTAEGIGAVKGYNVAAKTGTAENVGSSGSLTDTAATFTALIPAENPKIAVAVVIYKENGTVYGSTASAPVFVDIAQFAMREMKIPPSTVPLYKYPW
4s2w_A	1.992	MODELLER	-	161	P0A776	RPPH_ECOLI	E. coli	RNA pyrophosphohydrolase	True	True	True	True	False	25	30	45	SGDAEINMQTSSTPEFDG	CCHHHCCCCCCCCCCEEE	18	0.856	0.812	1.19	15.92	e4s2wA1	"""a+b two layers"""	221.4.1.3	1-161	1-161	"""beta-Grasp"""	"""-"""	"""Nudix"""	"""NUDIX_1"""	3.90.79.10	1-161	1-161	"""Alpha Beta"""	"""Alpha-Beta Complex"""	"""Nucleoside Triphosphate Pyrophosphohydrolase"""	"""Nucleoside Triphosphate Pyrophosphohydrolase"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1	n/a	1-161	1-161	SMIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLAA
4rcz_A	1.429	MODELLER	-	415	Q980A5	IF2G_SACS2	S. solfataricus	Translation initiation factor 2 subunit gamma	True	True	True	True	False	17	38	44	EELKRGMTI	HHHHHCCCC	9	0.936	0.93	0.97	22.82	e4rczA2, e4rczA1, e4rczA4, e4rczA3	"""beta barrels"", ""beta barrels"", ""a/b three-layered sandwiches"", ""few secondary structure elements"""	1.1.7.21, 1.1.8.1, 2004.1.1.258, 375.1.1.53	205-325, 326-415, 2-54,88-204, 55-87	205-325, 326-415, 2-54,88-204, 55-87	"""cradle loop barrel"", ""cradle loop barrel"", ""P-loop domains-like"", ""Rubredoxin-like"""	"""RIFT-related"", ""RIFT-related"", ""P-loop domains-related"", ""Rubredoxin-related"""	"""Alanine racemase-C"", ""Aminomethyltransferase beta-barrel domain"", ""P-loop containing nucleoside triphosphate hydrolases"", ""Rubredoxin-related"""	"""GTP_EFTU_D2_2"", ""eIF2_C"", ""MnmE_helical_2nd"", ""DUF35_N_like"""	2.40.30.10, 2.40.30.10, 3.40.50.300	208-322, 323-415, 2-207	208-322, 323-415, 2-207	"""Mainly Beta"", ""Mainly Beta"", ""Alpha Beta"""	"""Beta Barrel"", ""Beta Barrel"", ""3-Layer(aba) Sandwich"""	"""Elongation Factor Tu (Ef-tu); domain 3"", ""Elongation Factor Tu (Ef-tu); domain 3"", ""Rossmann fold"""	"""Translation factors"", ""Translation factors"", ""P-loop containing nucleotide triphosphate hydrolases"""	207-320, 321-415, 2-206	207-320, 321-415, 2-206	"""All beta proteins"", ""All beta proteins"", ""Alpha and beta proteins (a/b)"""	"""Reductase/isomerase/elongation factor common domain"", ""Elongation factor/aminomethyltransferase common domain"", ""P-loop containing nucleoside triphosphate hydrolases"""	"""Translation proteins"", ""EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"", ""P-loop containing nucleoside triphosphate hydrolases"""	"""-"", ""-"", ""G proteins"""	Optimal • Dom. n°1, Optimal • Dom. n°2, Optimal • Dom. n°3	****, ****, ****	1-206, 207-322, 323-415	1-206, 207-322, 323-415	MAWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI
6iqm_A	1.85	MODELLER	-	340	D7VA33	D7VA33_LACPN	L. plantarum subsp. plantarum ATCC 14917 = JCM 1149 = CGMCC 1.2437	Glyceraldehyde-3-phosphate dehydrogenase	True	True	True	True	False	28	27	45	QNIPWVKNDGVDF	HHCCHHHHHCCCE	13	0.867	0.865	1.76	21.44	e6iqmA1, e6iqmA2	"""a+b two layers"", ""a/b three-layered sandwiches"""	298.1.1.9, 2003.1.1.419	156-321, 1-155,322-340	156-321, 1-155,322-340	"""FwdE/GAPDH domain-like"", ""Rossmann-like"""	"""-"", ""Rossmann-related"""	"""Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"", ""NAD(P)-binding Rossmann-fold domains"""	"""Gp_dh_C_1"", ""Gp_dh_N_1"""	3.30.360.10	155-322	155-322	"""Alpha Beta"""	"""2-Layer Sandwich"""	"""Dihydrodipicolinate Reductase; domain 2"""	"""Dihydrodipicolinate Reductase; domain 2"""	-	-	"""-"""	"""-"""	"""-"""	"""-"""	Optimal • Dom. n°1, Optimal • Dom. n°2	****, ****	1-154,326-340, 155-325	1-154,326-340, 155-325	MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVGVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL
2zos_B	1.7	MODELLER	-	249	O58690	MPGP_PYRHO	P. horikoshii	Mannosyl-3-phosphoglycerate phosphatase	True	True	True	True	False	33	24	44	FDVKGKEVGN	CCCCCEEECC	10	0.913	0.934	1.04	19.19	e2zosB1, e2zosB2	"""a+b two layers"", ""a/b three-layered sandwiches"""	3012.1.1.16, 2006.1.1.75	94-176, 1-93,177-243	94-176, 1-93,177-243	"""-"", ""HAD domain-like"""	"""-"", ""HAD domain-related"""	"""Cof C2 cap domain"", ""HAD-like"""	"""UNK_F_TYPE"", ""Hydrolase_3"""	3.30.980.20, 3.40.50.1000	94-176, 2-93,177-243	94-176, 2-93,177-243	"""Alpha Beta"", ""Alpha Beta"""	"""2-Layer Sandwich"", ""3-Layer(aba) Sandwich"""	"""Threonyl-tRNA Synthetase; Chain A, domain 2"", ""Rossmann fold"""	"""Putative mannosyl-3-phosphoglycerate phosphatase; domain 2"", ""HAD superfamily/HAD-like"""	1-249	1-249	"""Alpha and beta proteins (a/b)"""	"""HAD-like"""	"""HAD-like"""	"""Predicted hydrolases Cof"""	Optimal • Dom. n°1, Optimal • Dom. n°2	***, ***	1-93,178-249, 94-177	1-93,178-249, 94-177	MIRLIFLDIDKTLIPGYEPDPAKPIIEELKDMGFEIIFNSSKTRAEQEYYRKELEVETPFISENGSAIFIPKGYFPFDVKGKEVGNYIVIELGIRVEKIREELKKLENIYGLKYYGNSTKEEIEKFTGMPPELVPLAMEREYSETIFEWSRDGWEEVLVEGGFKVTMGSRFYTVHGNSDKGKAAKILLDFYKRLGQIESYAVGDSYNDFPMFEVVDKVFIVGSLKHKKAQNVSSIIDVLEVIKHHHHHH