AGC: Subgroup of Ser/Thr protein kinases named after 3 representative families: the cAMP-dependent protein kinase (PKA), the cGMP-dependent protein kinase (PKG) and the protein kinase C (PKC) families
CAMK: Ca2+/calmodulin-dependent protein kinase
CK1: Casein kinase 1
CMGC: Cyclin-dependent kinase (CDK), mitogen-activated protein kinase (MAPK), glycogen synthase kinase (GSK) and CDC-like kinase (CLK)
NEK: NIMA (never in mitosis gene a)-related kinase
RGC: Receptor guanylate cyclases
STE: Serine/threonine kinases
TKL: Tyrosine kinase-like
TYR: Tyrosine kinase
Manning, G., Whyte, D. B., Martinez, R., Hunter, T. & Sudarsanam, S. The Protein Kinase Complement of the Human Genome. Science 298, 1912–1934 (2002)
Modi, V. & Dunbrack, R. L. A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains. Sci. Rep. 9, 19790 (2019)
LBCA: The last bacterial common ancestor
LACA: The last archaeal common ancestor
AECA: Archaea/eukaryota common ancestor
LECA: The last eukaryotic common ancestor
LGPCA: The last common ancestor of gamma-proteobacteria
LPBCA: The last common ancestor of cyanobacterial and deinococcus/thermus groups
LAFCA: The last common ancestor of animals and fungi
Perez-Jimenez, R. et al. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nat Struct Mol Biol 16 (2011).
Perez-Jimenez, R. et al. Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nat. Struct. Mol. Biol. 16, 890–896 (2009)