Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				S(Ser) 2
			

			

				Annotation dbPTM details
				N-acetylserine.
Phosphoserine.
Phosphoserine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				2KWO
			

			

				Model
				1
			

			

				Chain
				B
			

			

				Position
				1
			

			

				SCOP Class
				None
			

			

				MODRES
				N-ACETYL-SERINE                          
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
  *******************                                                                                  
-XGRGKGGKGLGKGGAKRHRK----------------------------------------------------------------------------------
 H___________________                                                                                  
 CCCCSSSSCSCSSCSCCCCC                                                                                  
 ZZiaadjklpmnoopghiZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XGRGKGGKGLGKGGAKRHRK 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				



This structure was solved By NMR.
The PDB records below correspond to the MODEL 1.


MODRES 2KWO SAC B    1  SER  N-ACETYL-SERINE                                    
LINK         C   SAC B   1                 N   GLY B   2     1555   1555  1.33  
HETATM    1  C1A SAC B   1       6.398   5.235  -0.718  1.00  0.00           C  
HETATM    2  C2A SAC B   1       7.559   4.950  -1.677  1.00  0.00           C  
HETATM    3  OAC SAC B   1       5.533   6.045  -1.055  1.00  0.00           O  
HETATM    4  N   SAC B   1       6.323   4.561   0.427  1.00  0.00           N  
HETATM    5  CA  SAC B   1       5.113   4.593   1.247  1.00  0.00           C  
HETATM    6  C   SAC B   1       4.872   5.995   1.794  1.00  0.00           C  
HETATM    7  O   SAC B   1       5.788   6.817   1.842  1.00  0.00           O  
HETATM    8  CB  SAC B   1       5.211   3.584   2.395  1.00  0.00           C  
HETATM    9  OG  SAC B   1       4.223   3.832   3.379  1.00  0.00           O  
HETATM   10  H1  SAC B   1       7.035   3.926   0.654  1.00  0.00           H  
HETATM   11 H2A1 SAC B   1       7.359   5.415  -2.632  1.00  0.00           H  
HETATM   12 H2A2 SAC B   1       7.663   3.885  -1.810  1.00  0.00           H  
HETATM   13 H2A3 SAC B   1       8.472   5.353  -1.267  1.00  0.00           H  
HETATM   14  HA  SAC B   1       4.278   4.323   0.614  1.00  0.00           H  
HETATM   15  HB2 SAC B   1       5.068   2.587   2.007  1.00  0.00           H  
HETATM   16  HB3 SAC B   1       6.185   3.653   2.853  1.00  0.00           H  
HETATM   17  HG  SAC B   1       4.040   3.022   3.861  1.00  0.00           H