Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 17
			

			

				Annotation dbPTM details
				N6-acetyllysine.
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				3QZS
			

			

				Model
				-
			

			

				Chain
				C
			

			

				Position
				16
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
            **** *****                                                                                 
------------KGGAXRHRKV---------------------------------------------------------------------------------
            MM__H_____                                                                                 
              CCCCCCCC                                                                                 
              ZZdddfZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XXGAXRHRKV 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 3QZS ALY C   16  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   ALA C  15                 N   ALY C  16     1555   1555  1.33  
LINK         C   ALY C  16                 N   ARG C  17     1555   1555  1.33  
HETATM 1862  OH  ALY C  16      10.869   7.643   7.313  1.00 11.39           O  
ANISOU 1862  OH  ALY C  16     2535   1002    790    -60   -240    -63       O  
HETATM 1863  CH  ALY C  16      12.042   7.868   7.519  1.00 15.07           C  
ANISOU 1863  CH  ALY C  16     2997   1374   1355    -89   -471    -60       C  
HETATM 1864  CH3 ALY C  16      12.578   7.723   8.901  1.00 12.20           C  
ANISOU 1864  CH3 ALY C  16     2829   1055    750    -51   -677   -125       C  
HETATM 1865  NZ  ALY C  16      12.864   8.266   6.555  1.00 16.15           N  
ANISOU 1865  NZ  ALY C  16     2925   1413   1797   -139   -553     43       N  
HETATM 1866  CE  ALY C  16      12.243   8.340   5.244  1.00 17.27           C  
ANISOU 1866  CE  ALY C  16     2879   1662   2020   -136   -345    133       C  
HETATM 1867  CD  ALY C  16      12.182   9.705   4.632  1.00 23.53           C  
ANISOU 1867  CD  ALY C  16     3487   2377   3077   -154   -401    228       C  
HETATM 1868  CG  ALY C  16      11.523   9.654   3.230  1.00 18.80           C  
ANISOU 1868  CG  ALY C  16     2681   2013   2448   -136   -192    389       C  
HETATM 1869  CB  ALY C  16      12.520   9.290   2.171  1.00 20.17           C  
ANISOU 1869  CB  ALY C  16     2597   2438   2628   -103   -149    617       C  
HETATM 1870  CA  ALY C  16      11.965   9.158   0.734  1.00 19.64           C  
ANISOU 1870  CA  ALY C  16     2319   2772   2369    -17     31    736       C  
HETATM 1871  N   ALY C  16      13.190   9.021  -0.094  1.00 25.44           N  
ANISOU 1871  N   ALY C  16     2762   3826   3077     67     82    981       N  
HETATM 1872  C   ALY C  16      10.988  10.187   0.169  1.00 19.23           C  
ANISOU 1872  C   ALY C  16     2139   2764   2404    -52     56    928       C  
HETATM 1873  O   ALY C  16      11.382  11.323  -0.213  1.00 20.95           O  
ANISOU 1873  O   ALY C  16     2076   2968   2916   -107    -17   1324       O