Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 17
			

			

				Annotation dbPTM details
				N6-acetyllysine.
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				3QZS
			

			

				Model
				-
			

			

				Chain
				D
			

			

				Position
				16
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
            **** *****                                                                                 
------------KGGAXRHRKV---------------------------------------------------------------------------------
            MM__H_____                                                                                 
              CCCCCCCC                                                                                 
              ZZcddfZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XXGAXRHRKV 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 3QZS ALY D   16  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   ALA D  15                 N   ALY D  16     1555   1555  1.33  
LINK         C   ALY D  16                 N   ARG D  17     1555   1555  1.32  
HETATM 1933  OH  ALY D  16     -12.059  -2.498  34.748  1.00 15.62           O  
ANISOU 1933  OH  ALY D  16     2392   2186   1356    -27    354    337       O  
HETATM 1934  CH  ALY D  16     -10.870  -2.688  34.564  1.00 17.75           C  
ANISOU 1934  CH  ALY D  16     2543   2583   1619     13    516    453       C  
HETATM 1935  CH3 ALY D  16     -10.198  -2.454  33.240  1.00 15.33           C  
ANISOU 1935  CH3 ALY D  16     2419   2170   1234    154    738    539       C  
HETATM 1936  NZ  ALY D  16     -10.063  -3.042  35.538  1.00 18.91           N  
ANISOU 1936  NZ  ALY D  16     2376   2983   1826    -52    523    537       N  
HETATM 1937  CE  ALY D  16     -10.621  -3.216  36.863  1.00 21.26           C  
ANISOU 1937  CE  ALY D  16     2551   3365   2161   -169    346    465       C  
HETATM 1938  CD  ALY D  16     -10.689  -4.576  37.465  1.00 20.98           C  
ANISOU 1938  CD  ALY D  16     2459   3398   2116     -6    298    516       C  
HETATM 1939  CG  ALY D  16     -11.274  -4.445  38.900  1.00 20.97           C  
ANISOU 1939  CG  ALY D  16     2370   3457   2141   -152    154    442       C  
HETATM 1940  CB  ALY D  16     -10.202  -4.447  39.986  1.00 20.84           C  
ANISOU 1940  CB  ALY D  16     2077   3747   2096   -235    111    535       C  
HETATM 1941  CA  ALY D  16     -10.753  -4.096  41.371  1.00 20.36           C  
ANISOU 1941  CA  ALY D  16     2045   3696   1996   -389    -19    447       C  
HETATM 1942  N   ALY D  16      -9.600  -3.962  42.283  1.00 24.99           N  
ANISOU 1942  N   ALY D  16     2387   4597   2512   -510   -127    533       N  
HETATM 1943  C   ALY D  16     -11.813  -5.065  41.901  1.00 17.65           C  
ANISOU 1943  C   ALY D  16     1842   3200   1664   -228    -18    418       C  
HETATM 1944  O   ALY D  16     -11.523  -6.228  42.213  1.00 18.40           O  
ANISOU 1944  O   ALY D  16     1893   3371   1726    -38      8    511       O