Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 17
			

			

				Annotation dbPTM details
				N6-acetyllysine.
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				3QZT
			

			

				Model
				-
			

			

				Chain
				B
			

			

				Position
				16
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
Sort by:
PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012


MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
            **** *****                                                                                 
------------KGGAXRHRKV---------------------------------------------------------------------------------
            MM__H___MM                                                                                 
              CCCCCC                                                                                   
              ZZddZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XXGAXRHRXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 3QZT ALY B   16  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   ALA B  15                 N   ALY B  16     1555   1555  1.32  
LINK         C   ALY B  16                 N   ARG B  17     1555   1555  1.32  
HETATM  956  OH  ALY B  16      24.246   2.921  10.348  1.00 13.84           O  
ANISOU  956  OH  ALY B  16     1649   1961   1646   -174      9      7       O  
HETATM  957  CH  ALY B  16      24.296   2.979  11.542  1.00 13.58           C  
ANISOU  957  CH  ALY B  16     1606   1868   1683   -141     29    -18       C  
HETATM  958  CH3 ALY B  16      23.119   2.510  12.345  1.00 16.35           C  
ANISOU  958  CH3 ALY B  16     1959   2185   2068   -169     28    -58       C  
HETATM  959  NZ  ALY B  16      25.354   3.433  12.196  1.00 19.15           N  
ANISOU  959  NZ  ALY B  16     2305   2539   2430    -97     51     -9       N  
HETATM  960  CE  ALY B  16      26.466   3.948  11.373  1.00 23.57           C  
ANISOU  960  CE  ALY B  16     2845   3133   2979    -72     61     40       C  
HETATM  961  CD  ALY B  16      27.838   4.213  11.916  1.00 27.85           C  
ANISOU  961  CD  ALY B  16     3372   3639   3572    -30     79     62       C  
HETATM  962  CG  ALY B  16      28.659   4.501  10.671  1.00 28.81           C  
ANISOU  962  CG  ALY B  16     3471   3810   3664    -20    112    107       C  
HETATM  963  CB  ALY B  16      29.993   3.821  10.766  1.00 33.58           C  
ANISOU  963  CB  ALY B  16     4075   4379   4305     22    173    100       C  
HETATM  964  CA  ALY B  16      31.041   4.839  10.394  1.00 33.72           C  
ANISOU  964  CA  ALY B  16     4023   4413   4378     41    183    179       C  
HETATM  965  N   ALY B  16      31.348   4.550   9.003  1.00 36.97           N  
ANISOU  965  N   ALY B  16     4456   4878   4712     28    272    172       N  
HETATM  966  C   ALY B  16      32.160   4.596  11.327  1.00 33.12           C  
ANISOU  966  C   ALY B  16     3904   4268   4410     78    175    207       C  
HETATM  967  O   ALY B  16      32.990   3.702  11.118  1.00 34.46           O  
ANISOU  967  O   ALY B  16     4059   4404   4629    113    245    201       O