Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 17
			

			

				Annotation dbPTM details
				N6-acetyllysine.
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				3UVX
			

			

				Model
				-
			

			

				Chain
				B
			

			

				Position
				16
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				12
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
           * *** *****                                                                                 
-----------GXGGAXRHRKV---------------------------------------------------------------------------------
           _H___H_MMMM                                                                                 
           CCCSCCC                                                                                     
           ZZbcfZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
GXGGAXRXXXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

REMARK 500    ALY B  16   O   -  C   -  N   ANGL. DEV. = -21.9 DEGREES          
REMARK 500    ALY B  16         27.94                                           
MODRES 3UVX ALY B   16  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   ALA B  15                 N   ALY B  16     1555   1555  1.34  
LINK         C   ALY B  16                 N   ARG B  17     1555   1555  1.38  
HETATM 1107  OH  ALY B  16      28.582  38.317  22.867  1.00 41.47           O  
HETATM 1108  CH  ALY B  16      27.796  38.009  23.753  1.00 56.71           C  
HETATM 1109  CH3 ALY B  16      26.776  36.931  23.537  1.00 46.69           C  
HETATM 1110  NZ  ALY B  16      27.800  38.598  24.961  1.00 37.90           N  
HETATM 1111  CE  ALY B  16      28.681  39.670  25.441  1.00 39.69           C  
HETATM 1112  CD  ALY B  16      29.913  39.026  26.084  1.00 32.67           C  
HETATM 1113  CG  ALY B  16      29.608  38.587  27.519  1.00 39.96           C  
HETATM 1114  CB  ALY B  16      30.778  37.874  28.185  1.00 38.97           C  
HETATM 1115  CA  ALY B  16      30.447  37.391  29.603  1.00 39.56           C  
HETATM 1116  N   ALY B  16      30.174  38.512  30.493  1.00 45.02           N  
HETATM 1117  C   ALY B  16      31.551  36.559  30.251  1.00 56.50           C  
HETATM 1118  O   ALY B  16      32.037  35.630  29.589  1.00 50.95           O