Sequence     &     Structural     Information
	
PTM
PTM Acetylation
Sequence Information
Uniprot AC P62805
Organism HUMAN (Human)
Modified Amino Acid K(Lys) 17
Annotation dbPTM details N6-acetyllysine.
N6-acetyllysine
Structure Information
PDB ID Code 3UVY
Model -
Chain B
Position 16
SCOP Class None
MODRES N(6)-ACETYLLYSINE
Related PTM
Found in same PDB Chain 20
Found in same Uniprot AC
Sort by: PDB ID Code (idpdb-chain_aa) Sequence position (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?)

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
               * *** *****                                                                             
---------------AXRHRXVLRDN-----------------------------------------------------------------------------
               _H___H____M                                                                             
               CCCCCCSCCC                                                                              
               ZZccfbdcZZ                                                                              

Scripts     (PyMol,     Modeller,     ...)

PyMol
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Modeller
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
			
AXRHRXVLRDX
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			
REMARK 500 ALY B 16 O - C - N ANGL. DEV. = -12.8 DEGREES
REMARK 500 ALY B 16 72.60 -104.04
REMARK 500 ALY B 16 25.01
MODRES 3UVY ALY B 16 LYS N(6)-ACETYLLYSINE
LINK C ALA B 15 N ALY B 16 1555 1555 1.31
LINK C ALY B 16 N ARG B 17 1555 1555 1.32
HETATM 926 OH ALY B 16 68.911 23.491 15.917 1.00 19.26 O
HETATM 927 CH ALY B 16 69.117 23.369 14.728 1.00 27.06 C
HETATM 928 CH3 ALY B 16 68.034 23.474 13.689 1.00 13.18 C
HETATM 929 NZ ALY B 16 70.347 23.132 14.331 1.00 20.29 N
HETATM 930 CE ALY B 16 71.477 22.998 15.252 1.00 18.08 C
HETATM 931 CD ALY B 16 72.475 24.107 14.954 1.00 22.23 C
HETATM 932 CG ALY B 16 73.692 24.034 15.849 1.00 25.64 C
HETATM 933 CB ALY B 16 73.263 24.294 17.260 1.00 16.36 C
HETATM 934 CA ALY B 16 74.306 24.922 18.162 1.00 21.40 C
HETATM 935 N ALY B 16 73.723 24.967 19.518 1.00 24.05 N
HETATM 936 C ALY B 16 74.716 26.284 17.598 1.00 29.79 C
HETATM 937 O ALY B 16 73.839 27.161 17.450 1.00 28.59 O