Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 13
			

			

				Annotation dbPTM details
				N6-acetyllysine.
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				4N4F
			

			

				Model
				-
			

			

				Chain
				C
			

			

				Position
				12
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
Sort by:
PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
     ******* *** *********                                                                             
-----KGGKGLGXGGAXRHRKVLRDN-----------------------------------------------------------------------------
     MM_____HMMMMMMMMMMMMM                                                                             
       CCCCCC                                                                                          
       ZZcdZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XXGKGLGXXXXXXXXXXXXXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 4N4F ALY C   12  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   GLY C  11                 N   ALY C  12     1555   1555  1.32  
HETATM 1613  OH  ALY C  12     -25.735  11.402 -12.721  1.00 32.08           O  
HETATM 1614  CH  ALY C  12     -26.583  11.152 -13.550  1.00 32.87           C  
HETATM 1615  CH3 ALY C  12     -26.854   9.799 -14.150  1.00 30.85           C  
HETATM 1616  NZ  ALY C  12     -27.370  12.114 -13.942  1.00 30.64           N  
HETATM 1617  CE  ALY C  12     -27.275  13.520 -13.445  1.00 29.85           C  
HETATM 1618  CD  ALY C  12     -28.615  14.132 -12.980  1.00 32.81           C  
HETATM 1619  CG  ALY C  12     -28.411  15.471 -12.236  1.00 35.14           C  
HETATM 1620  CB  ALY C  12     -29.786  15.865 -11.666  1.00 39.16           C  
HETATM 1621  CA  ALY C  12     -29.743  17.283 -11.163  1.00 39.94           C  
HETATM 1622  N   ALY C  12     -28.826  17.358 -10.058  1.00 36.25           N  
HETATM 1623  C   ALY C  12     -31.118  17.653 -10.690  1.00 46.57           C  
HETATM 1624  O   ALY C  12     -32.092  17.768 -11.468  1.00 49.53           O  
TER    1625      ALY C  12