Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 13
			

			

				Annotation dbPTM details
				N6-acetyllysine.
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				4QUT
			

			

				Model
				-
			

			

				Chain
				B
			

			

				Position
				12
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
         *** ***                                   *                                                   
---------GLGXGGA-----------------------------------Y---------------------------------------------------
         ___H_MM                                   M                                                   
         CCCCC                                                                                         
         ZZjZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
GLGXGXXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 4QUT ALY B   12  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   GLY B  11                 N   ALY B  12     1555   1555  1.33  
LINK         C   ALY B  12                 N   GLY B  13     1555   1555  1.33  
HETATM 1196  OH  ALY B  12      24.385  43.471 -11.689  1.00 18.34           O  
ANISOU 1196  OH  ALY B  12     2144   2694   2130     11    171     82       O  
HETATM 1197  CH  ALY B  12      24.640  44.326 -10.819  1.00 20.20           C  
ANISOU 1197  CH  ALY B  12     2362   2909   2403    -32    198     66       C  
HETATM 1198  CH3 ALY B  12      23.837  44.415  -9.539  1.00 20.35           C  
ANISOU 1198  CH3 ALY B  12     2375   2909   2447    -39    159     56       C  
HETATM 1199  NZ  ALY B  12      25.600  45.245 -10.982  1.00 22.89           N  
ANISOU 1199  NZ  ALY B  12     2692   3242   2765    -82    270     53       N  
HETATM 1200  CE  ALY B  12      26.352  45.252 -12.239  1.00 25.84           C  
ANISOU 1200  CE  ALY B  12     3077   3627   3115    -76    319     68       C  
HETATM 1201  CD  ALY B  12      27.235  46.488 -12.479  1.00 30.37           C  
ANISOU 1201  CD  ALY B  12     3652   4167   3719   -141    425     57       C  
HETATM 1202  CG  ALY B  12      28.565  46.397 -11.809  1.00 32.83           C  
ANISOU 1202  CG  ALY B  12     3875   4541   4057   -205    440    -18       C  
HETATM 1203  CB  ALY B  12      29.367  47.708 -11.892  1.00 33.44           C  
ANISOU 1203  CB  ALY B  12     3948   4581   4178   -298    558    -50       C  
HETATM 1204  CA  ALY B  12      29.921  48.024 -13.274  1.00 33.54           C  
ANISOU 1204  CA  ALY B  12     3999   4566   4177   -295    647    -14       C  
HETATM 1205  N   ALY B  12      30.535  46.855 -13.874  1.00 30.62           N  
ANISOU 1205  N   ALY B  12     3588   4278   3768   -246    599    -16       N  
HETATM 1206  C   ALY B  12      30.924  49.170 -13.193  1.00 41.36           C  
ANISOU 1206  C   ALY B  12     4967   5527   5221   -407    774    -69       C  
HETATM 1207  O   ALY B  12      30.716  50.134 -12.449  1.00 43.38           O  
ANISOU 1207  O   ALY B  12     5237   5724   5522   -476    827   -101       O