Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 6
			

			

				Annotation dbPTM details
				N6-acetyllysine.
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				4QUU
			

			

				Model
				-
			

			

				Chain
				B
			

			

				Position
				5
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
   ** ** *** ***                                                                                       
---RGXGGXGLGXGGAY--------------------------------------------------------------------------------------
   __H__MMMMMMMMM                                                                                      
   CCCCC                                                                                               
   ZZeZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
RGXGGXXXXXXXXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 4QUU ALY B    5  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   GLY B   4                 N   ALY B   5     1555   1555  1.33  
LINK         C   ALY B   5                 N   GLY B   6     1555   1555  1.34  
HETATM 1182  OH  ALY B   5      24.068  43.444 -11.689  1.00 27.26           O  
ANISOU 1182  OH  ALY B   5     2960   4491   2905     81    345    447       O  
HETATM 1183  CH  ALY B   5      24.194  44.348 -10.891  1.00 27.96           C  
ANISOU 1183  CH  ALY B   5     3025   4514   3083    -18    378    437       C  
HETATM 1184  CH3 ALY B   5      23.382  44.419  -9.617  1.00 27.66           C  
ANISOU 1184  CH3 ALY B   5     3010   4398   3101    -61    311    375       C  
HETATM 1185  NZ  ALY B   5      24.998  45.381 -11.030  1.00 30.93           N  
ANISOU 1185  NZ  ALY B   5     3357   4871   3523   -102    484    470       N  
HETATM 1186  CE  ALY B   5      25.850  45.594 -12.177  1.00 34.56           C  
ANISOU 1186  CE  ALY B   5     3789   5389   3952    -81    582    543       C  
HETATM 1187  CD  ALY B   5      27.187  45.002 -11.864  1.00 35.96           C  
ANISOU 1187  CD  ALY B   5     3850   5694   4120   -112    574    479       C  
HETATM 1188  CG  ALY B   5      28.020  45.098 -13.100  1.00 36.94           C  
ANISOU 1188  CG  ALY B   5     3946   5889   4202    -75    673    557       C  
HETATM 1189  CB  ALY B   5      29.430  44.696 -12.745  1.00 38.35           C  
ANISOU 1189  CB  ALY B   5     3984   6207   4380   -117    681    493       C  
HETATM 1190  CA  ALY B   5      30.261  44.414 -13.983  1.00 39.75           C  
ANISOU 1190  CA  ALY B   5     4130   6487   4485    -44    758    566       C  
HETATM 1191  N   ALY B   5      29.634  43.365 -14.791  1.00 37.16           N  
ANISOU 1191  N   ALY B   5     3896   6192   4032    122    689    598       N  
HETATM 1192  C   ALY B   5      31.637  43.998 -13.530  1.00 44.42           C  
ANISOU 1192  C   ALY B   5     4567   7239   5072    -78    759    495       C  
HETATM 1193  O   ALY B   5      32.488  44.856 -13.284  1.00 47.67           O  
ANISOU 1193  O   ALY B   5     4867   7674   5572   -216    851    470       O