Sequence     &     Structural     Information 
	

		
			

				PTM
			

		
		
			

				PTM
				Acetylation
			

		

		
			

				Sequence Information
			


		
		
			

				Uniprot AC
				P62805
			

			

				Organism
				HUMAN (Human)
			

			

				Modified Amino Acid
				K(Lys) 13
			

			

				Annotation dbPTM details
				N6-acetyllysine.
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
N6-acetyllysine		
			

		

		
			

				Structure Information
			


		
		
			

				PDB ID Code
				4QYD
			

			

				Model
				-
			

			

				Chain
				B
			

			

				Position
				12
			

			

				SCOP Class
				None
			

			

				MODRES
				N(6)-ACETYLLYSINE                        
			

		

		
			

				Related PTM
			


		
		
			

				Found in same PDB Chain
				-
			

			

				Found in same Uniprot AC
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PDB ID Code
  (idpdb-chain_aa)
Sequence position
  (aa_idpdb-chain)
Gallery (?)
Slide 1
Slide 2
Example Frame 



Note: As the images production is automatic, the focus on the PTM site could not be the most optimized.
      In these cases it is recommended to use the PyMOL script to visualize the PTM site in 3D.
Alignment
(?) 

	           Numerotation

	(?)       Uniprot Sequence
	(?)                Clustal
	(?)           PDB Sequence
	(?)        PDB Information
	(?)          DSSP Sequence
	(?) Protein Block Sequence
	
         1         2         3         4         5         6         7         8         9         10        
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MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
    ******** *****                                                                                     
----GKGGKGLGXGGAKR-------------------------------------------------------------------------------------
    MM______H_MMMM                                                                                     
      CCCCSCCC                                                                                         
      ZZdfbjZZ

Scripts     (PyMol,     Modeller,     ...)

PyMol 
	Download
Modeller 
	
If you want to use this structure as a template for modelisation with Modeller, you can use the following sequence to build the alignment file "*.ali".

To avoid the classical Modeller error :

			'Number of residues in the alignment and pdb files are different'(see FAQ n°17),

the missing residues, non-classical amino-acids, and sequence gaps have been replaced by a "X" symbol.
XXGGKGLGXGXXXX 
1) align this sequence with your sequence to modelised;
2) replace the "X" by "-" in the obtained alignement, then build your "*.ali" file;
3) use Modeller to make your models;
4) And finally use the following information found in the PDB to add this PTM in your models (see FAQ n°8 & 9 and this archive of Modeller usage).
			

			

			
				

MODRES 4QYD ALY B   12  LYS  N(6)-ACETYLLYSINE                                  
LINK         C   GLY B  11                 N   ALY B  12     1555   1555  1.33  
LINK         C   ALY B  12                 N   GLY B  13     1555   1555  1.33  
HETATM  981  OH  ALY B  12       5.081  95.171  97.864  1.00 23.66           O  
ANISOU  981  OH  ALY B  12     2595   3080   3313    454    845    172       O  
HETATM  982  CH  ALY B  12       5.646  95.269  98.949  1.00 28.17           C  
ANISOU  982  CH  ALY B  12     3054   3549   4102    375    682    214       C  
HETATM  983  CH3 ALY B  12       6.956  94.583  99.210  1.00 25.05           C  
ANISOU  983  CH3 ALY B  12     2569   2999   3951    386    803    513       C  
HETATM  984  NZ  ALY B  12       5.168  95.978  99.978  1.00 23.37           N  
ANISOU  984  NZ  ALY B  12     2404   2965   3509    297    391     19       N  
HETATM  985  CE  ALY B  12       3.924  96.748  99.928  1.00 21.60           C  
ANISOU  985  CE  ALY B  12     2227   2875   3105    324    285   -217       C  
HETATM  986  CD  ALY B  12       2.695  95.834 100.001  1.00 22.84           C  
ANISOU  986  CD  ALY B  12     2513   3279   2888    271    375   -431       C  
HETATM  987  CG  ALY B  12       1.388  96.610  99.799  1.00 25.65           C  
ANISOU  987  CG  ALY B  12     2856   3803   3087    322    307   -568       C  
HETATM  988  CB  ALY B  12       1.147  97.663 100.883  1.00 25.30           C  
ANISOU  988  CB  ALY B  12     2785   3708   3120    398    110   -697       C  
HETATM  989  CA  ALY B  12      -0.335  98.068 100.980  1.00 24.37           C  
ANISOU  989  CA  ALY B  12     2658   3810   2793    484    122   -811       C  
HETATM  990  N   ALY B  12      -0.769  98.703  99.745  1.00 24.83           N  
ANISOU  990  N   ALY B  12     2630   3915   2888    537    184   -689       N  
HETATM  991  C   ALY B  12      -0.502  98.981 102.166  1.00 34.07           C  
ANISOU  991  C   ALY B  12     3948   4957   4039    623    -21   -978       C  
HETATM  992  O   ALY B  12      -0.317  98.535 103.316  1.00 45.42           O  
ANISOU  992  O   ALY B  12     5476   6427   5354    624    -88  -1090       O