############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:22:10 Total request time: 13.0 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|A6NFX1|MFS2B_HUMAN Major facilitator superfamily domain-containing protein 2B OS=Homo sapiens GN=MFSD2B PE=2 SV=3 Sequence length: 497 aa. Sequence: MAAPPAPAAKGSPQPEPHAPEPGPGSAKRGREDSRAGRLSFCTKVCYGIGGVPNQIASSATAFYLQLFLLDIAQIPAAQVSLVLFGGKVSGAAADPVAGFFINRSQRTGSGRLMPWVLGCTPFIALAYFFLWFLPPFTSLRGLWYTTFYCLFQALATFFQVPYTALTMLLTPCPRERDSATAYRMTVEMAGTLMGATVHGLIVSGAHRPHRCEATATPGPVTVSPNAAHLYCIAAAVVVVTYPVCISLLCLGVKERPDPSAPASGPGLSFLAGLSLTTRHPPYLKLVISFLFISAAVQVEQSYLVLFCTHASQLHDHVQGLVLTVLVSAVLSTPLWEWVLQRFGKKTSAFGIFAMVPFAILLAAVPTAPVAYVVAFVSGVSIAVSLLLPWSMLPDVVDDFQLQHRHGPGLETIFYSSYVFFTKLSGACALGISTLSLEFSGYKAGVCKQAEEVVVTLKVLIGAVPTCMILAGLCILMVGSTPKTPSRDASSRLSLRR TOPCONS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii OCTOPUS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooo Philius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMooooooooooMMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiii PolyPhobius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMoooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii SCAMPI predicted topology: oooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiMMMMMMMMMMMMMMMMMMMMMooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii SPOCTOPUS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooo 4m64B: --------------------------------------iiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMMMMiiiiiii-iiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 11.889 11 12.545 12 13.508 13 14.011 14 13.869 15 14.056 16 14.371 17 14.042 18 13.904 19 14.023 20 13.576 21 13.366 22 12.980 23 13.275 24 13.222 25 13.534 26 13.621 27 13.758 28 13.876 29 14.258 30 13.545 31 13.024 32 12.067 33 11.404 34 10.449 35 9.757 36 8.990 37 8.561 38 7.849 39 7.689 40 6.706 41 6.557 42 6.135 43 5.551 44 5.504 45 6.152 46 6.714 47 6.294 48 6.241 49 6.893 50 6.629 51 6.706 52 6.546 53 6.411 54 5.957 55 6.037 56 5.704 57 6.373 58 5.846 59 5.696 60 4.911 61 4.052 62 4.145 63 3.484 64 2.714 65 2.731 66 2.850 67 3.185 68 2.927 69 2.514 70 2.885 71 2.935 72 3.502 73 3.626 74 3.724 75 3.511 76 2.609 77 3.218 78 3.572 79 3.888 80 3.962 81 3.977 82 4.490 83 4.575 84 4.349 85 4.600 86 4.744 87 5.405 88 5.667 89 5.570 90 6.191 91 5.778 92 5.945 93 5.787 94 6.688 95 6.762 96 6.579 97 6.722 98 6.409 99 6.543 100 6.821 101 7.296 102 8.067 103 8.588 104 8.687 105 8.663 106 8.757 107 8.590 108 8.246 109 7.017 110 7.193 111 7.176 112 6.980 113 6.694 114 5.950 115 4.974 116 4.183 117 3.367 118 3.045 119 2.448 120 1.527 121 0.634 122 0.243 123 0.204 124 -0.217 125 -1.019 126 -0.349 127 0.392 128 0.897 129 0.949 130 1.634 131 1.425 132 1.120 133 1.740 134 1.463 135 1.300 136 1.474 137 1.568 138 1.908 139 2.319 140 2.907 141 3.664 142 3.692 143 3.522 144 4.377 145 3.778 146 3.045 147 3.086 148 2.798 149 1.848 150 1.547 151 1.923 152 1.511 153 2.310 154 2.446 155 2.502 156 2.522 157 2.431 158 2.944 159 3.225 160 3.041 161 2.954 162 3.183 163 3.006 164 3.060 165 3.820 166 3.757 167 4.155 168 4.350 169 5.076 170 5.376 171 6.095 172 6.655 173 7.635 174 8.249 175 8.708 176 9.185 177 9.167 178 8.946 179 9.522 180 9.622 181 9.288 182 9.042 183 8.766 184 7.625 185 7.040 186 6.137 187 5.460 188 4.531 189 3.862 190 4.371 191 4.614 192 4.408 193 4.337 194 4.192 195 4.290 196 4.332 197 4.123 198 3.906 199 3.914 200 4.300 201 4.885 202 5.110 203 5.823 204 6.974 205 7.342 206 8.092 207 8.793 208 9.412 209 9.830 210 9.995 211 10.653 212 10.489 213 10.135 214 9.401 215 9.197 216 9.326 217 8.881 218 8.662 219 7.986 220 7.818 221 7.480 222 7.349 223 6.779 224 6.607 225 6.534 226 6.455 227 6.291 228 5.520 229 4.977 230 4.319 231 3.974 232 3.592 233 3.081 234 2.842 235 1.940 236 1.164 237 0.944 238 1.385 239 0.680 240 0.995 241 1.333 242 1.132 243 1.463 244 1.362 245 1.584 246 2.216 247 2.367 248 3.048 249 3.956 250 5.029 251 6.120 252 7.068 253 8.017 254 8.944 255 9.950 256 10.855 257 11.101 258 11.694 259 11.354 260 11.287 261 10.864 262 9.640 263 9.000 264 8.535 265 6.927 266 6.734 267 5.535 268 4.769 269 4.028 270 3.598 271 4.228 272 4.189 273 4.765 274 4.765 275 4.340 276 4.662 277 4.719 278 5.895 279 6.035 280 6.924 281 7.082 282 6.537 283 5.590 284 5.350 285 4.616 286 4.268 287 3.589 288 2.875 289 2.632 290 1.745 291 1.847 292 1.904 293 2.596 294 3.192 295 2.925 296 3.547 297 3.537 298 3.703 299 3.699 300 4.245 301 5.172 302 5.344 303 5.698 304 5.705 305 5.349 306 5.797 307 6.301 308 6.465 309 6.730 310 7.141 311 7.531 312 7.366 313 7.836 314 7.903 315 7.968 316 8.211 317 7.757 318 7.333 319 7.133 320 6.106 321 5.562 322 4.183 323 3.366 324 3.260 325 2.970 326 1.954 327 0.965 328 1.629 329 0.972 330 1.008 331 1.298 332 2.366 333 3.408 334 3.714 335 4.514 336 5.559 337 6.111 338 6.288 339 7.204 340 7.730 341 8.322 342 8.555 343 8.410 344 7.444 345 7.529 346 7.223 347 5.991 348 5.959 349 5.023 350 4.556 351 3.156 352 2.259 353 1.553 354 0.804 355 0.270 356 -0.173 357 0.242 358 -0.007 359 0.192 360 1.164 361 1.050 362 1.414 363 1.748 364 1.843 365 1.981 366 2.166 367 1.788 368 2.160 369 2.473 370 2.758 371 3.108 372 3.557 373 3.241 374 2.995 375 2.709 376 2.508 377 1.942 378 1.539 379 0.756 380 1.353 381 1.288 382 1.668 383 1.711 384 1.457 385 1.962 386 2.907 387 3.305 388 3.296 389 3.902 390 4.879 391 4.862 392 5.977 393 6.030 394 6.894 395 7.372 396 7.991 397 9.434 398 10.463 399 10.831 400 11.631 401 10.956 402 11.499 403 11.823 404 11.069 405 10.312 406 9.759 407 9.440 408 8.664 409 7.836 410 7.700 411 6.659 412 6.574 413 6.099 414 5.653 415 5.382 416 5.263 417 5.304 418 4.744 419 4.441 420 4.663 421 3.479 422 3.692 423 3.622 424 4.053 425 3.915 426 2.973 427 2.871 428 2.303 429 2.659 430 2.597 431 3.138 432 3.511 433 3.229 434 3.832 435 3.748 436 4.012 437 4.348 438 4.684 439 5.317 440 6.661 441 6.667 442 7.781 443 8.531 444 8.851 445 9.349 446 9.120 447 9.494 448 8.408 449 8.721 450 8.231 451 7.342 452 6.989 453 6.771 454 6.431 455 5.785 456 6.005 457 5.834 458 5.315 459 4.739 460 4.356 461 2.925 462 2.093 463 2.247 464 1.618 465 1.396 466 1.073 467 0.718 468 0.205 469 0.063 470 0.599 471 0.930 472 0.511 473 0.957 474 1.366 475 1.154 476 1.987 477 3.032 478 3.762 479 4.937 480 6.072 481 7.342 482 8.117 483 9.310 484 9.677 485 10.667 486 10.953 487 10.881 488 10.567 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 80.00 12 80.00 13 80.00 14 80.00 15 80.00 16 80.00 17 80.00 18 80.00 19 80.00 20 80.00 21 80.00 22 80.00 23 80.00 24 80.00 25 80.00 26 80.00 27 80.00 28 80.00 29 80.00 30 80.00 31 80.00 32 80.00 33 80.00 34 80.00 35 79.05 36 78.10 37 76.19 38 74.29 39 73.33 40 73.33 41 73.33 42 73.33 43 73.33 44 73.33 45 73.33 46 74.29 47 75.24 48 76.19 49 77.14 50 78.10 51 79.05 52 80.00 53 80.95 54 81.90 55 82.86 56 83.81 57 84.76 58 86.67 59 88.57 60 88.57 61 88.57 62 88.57 63 88.57 64 88.57 65 88.57 66 88.57 67 86.67 68 83.81 69 80.95 70 78.10 71 75.24 72 72.38 73 69.52 74 66.67 75 63.81 76 60.95 77 59.05 78 57.14 79 55.24 80 53.33 81 52.38 82 50.48 83 48.57 84 46.67 85 44.76 86 42.86 87 40.95 88 40.00 89 40.00 90 40.00 91 40.00 92 40.00 93 40.00 94 40.00 95 40.00 96 40.00 97 40.00 98 40.00 99 40.00 100 40.00 101 40.00 102 40.00 103 40.00 104 42.86 105 45.71 106 48.57 107 51.43 108 54.29 109 57.14 110 60.00 111 62.86 112 65.71 113 68.57 114 71.43 115 74.29 116 77.14 117 80.00 118 82.86 119 85.71 120 88.57 121 91.43 122 94.29 123 97.14 124 100.00 125 97.14 126 94.29 127 91.43 128 88.57 129 85.71 130 82.86 131 80.00 132 77.14 133 74.29 134 72.38 135 71.43 136 70.48 137 69.52 138 68.57 139 67.62 140 66.67 141 65.71 142 64.76 143 63.81 144 62.86 145 61.90 146 63.81 147 65.71 148 67.62 149 69.52 150 71.43 151 73.33 152 75.24 153 77.14 154 79.05 155 79.05 156 78.10 157 77.14 158 76.19 159 75.24 160 74.29 161 73.33 162 72.38 163 71.43 164 70.48 165 69.52 166 68.57 167 67.62 168 66.67 169 65.71 170 64.76 171 63.81 172 62.86 173 61.90 174 60.95 175 60.00 176 60.00 177 60.00 178 60.00 179 60.00 180 60.00 181 60.00 182 60.00 183 60.00 184 60.00 185 60.00 186 60.00 187 60.00 188 60.00 189 60.00 190 60.00 191 60.00 192 60.00 193 60.00 194 60.95 195 62.86 196 64.76 197 66.67 198 68.57 199 70.48 200 72.38 201 74.29 202 76.19 203 78.10 204 80.00 205 81.90 206 83.81 207 85.71 208 87.62 209 89.52 210 91.43 211 93.33 212 95.24 213 97.14 214 99.05 215 100.00 216 100.00 217 99.05 218 98.10 219 97.14 220 96.19 221 96.19 222 96.19 223 96.19 224 96.19 225 96.19 226 96.19 227 96.19 228 96.19 229 96.19 230 96.19 231 96.19 232 96.19 233 96.19 234 96.19 235 96.19 236 96.19 237 96.19 238 97.14 239 98.10 240 99.05 241 100.00 242 99.05 243 99.05 244 99.05 245 99.05 246 99.05 247 99.05 248 99.05 249 99.05 250 99.05 251 99.05 252 99.05 253 99.05 254 99.05 255 99.05 256 99.05 257 99.05 258 99.05 259 99.05 260 99.05 261 99.05 262 99.05 263 100.00 264 100.00 265 100.00 266 100.00 267 100.00 268 100.00 269 100.00 270 100.00 271 100.00 272 99.05 273 96.19 274 96.19 275 96.19 276 96.19 277 96.19 278 96.19 279 96.19 280 96.19 281 96.19 282 96.19 283 96.19 284 96.19 285 96.19 286 96.19 287 96.19 288 96.19 289 96.19 290 96.19 291 96.19 292 96.19 293 96.19 294 98.10 295 97.14 296 96.19 297 96.19 298 96.19 299 96.19 300 96.19 301 96.19 302 96.19 303 96.19 304 96.19 305 96.19 306 96.19 307 96.19 308 95.24 309 94.29 310 94.29 311 94.29 312 94.29 313 94.29 314 95.24 315 96.19 316 97.14 317 98.10 318 98.10 319 98.10 320 98.10 321 98.10 322 98.10 323 98.10 324 98.10 325 98.10 326 98.10 327 98.10 328 98.10 329 96.19 330 95.24 331 95.24 332 95.24 333 95.24 334 95.24 335 95.24 336 95.24 337 93.33 338 91.43 339 89.52 340 87.62 341 85.71 342 83.81 343 81.90 344 81.90 345 81.90 346 81.90 347 81.90 348 81.90 349 81.90 350 84.76 351 86.67 352 86.67 353 86.67 354 86.67 355 86.67 356 85.71 357 83.81 358 83.81 359 83.81 360 83.81 361 84.76 362 86.67 363 88.57 364 90.48 365 90.48 366 90.48 367 90.48 368 90.48 369 90.48 370 90.48 371 90.48 372 90.48 373 90.48 374 90.48 375 88.57 376 86.67 377 85.71 378 85.71 379 85.71 380 85.71 381 83.81 382 80.95 383 78.10 384 76.19 385 74.29 386 72.38 387 70.48 388 68.57 389 66.67 390 64.76 391 62.86 392 60.95 393 59.05 394 57.14 395 55.24 396 55.24 397 55.24 398 55.24 399 55.24 400 55.24 401 55.24 402 57.14 403 58.10 404 57.14 405 55.24 406 53.33 407 55.24 408 57.14 409 59.05 410 60.95 411 62.86 412 64.76 413 66.67 414 68.57 415 70.48 416 72.38 417 74.29 418 76.19 419 78.10 420 80.00 421 81.90 422 83.81 423 85.71 424 88.57 425 92.38 426 95.24 427 98.10 428 96.19 429 94.29 430 92.38 431 90.48 432 88.57 433 86.67 434 84.76 435 82.86 436 80.95 437 79.05 438 77.14 439 75.24 440 73.33 441 71.43 442 69.52 443 67.62 444 65.71 445 63.81 446 60.95 447 59.05 448 57.14 449 58.10 450 59.05 451 60.00 452 61.90 453 63.81 454 65.71 455 67.62 456 69.52 457 71.43 458 73.33 459 75.24 460 77.14 461 79.05 462 80.95 463 82.86 464 84.76 465 86.67 466 88.57 467 89.52 468 90.48 469 91.43 470 88.57 471 86.67 472 84.76 473 82.86 474 80.95 475 79.05 476 77.14 477 75.24 478 73.33 479 71.43 480 69.52 481 67.62 482 65.71 483 63.81 484 61.90 485 60.00 486 58.10 ##############################################################################