############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:27:06 Total request time: 12.4 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|O15554|KCNN4_HUMAN Intermediate conductance calcium-activated potassium channel protein 4 OS=Homo sapiens GN=KCNN4 PE=1 SV=1 Sequence length: 427 aa. Sequence: MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK TOPCONS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii OCTOPUS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Philius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiMMMMMMMMMMMMMMMMMMooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii PolyPhobius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SCAMPI predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SPOCTOPUS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii 4twkB: ----------------------------------------------------------------------------------------------------------------------------------------------------iMMMMMMMMMMMMMMMMMMMMMMM--ooooooooooooooooooooooooooooooooooooooooooooooooooooooo--ooooooLLLLLLLLLLLLLLLLLooooooooMMMMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiii-------------------------------------------------------------------------------------------------------------------- Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 3.866 11 5.728 12 7.275 13 8.683 14 9.671 15 11.112 16 10.964 17 11.006 18 10.555 19 9.996 20 8.833 21 7.720 22 7.502 23 6.730 24 6.304 25 6.237 26 5.499 27 5.229 28 4.807 29 4.878 30 3.165 31 2.281 32 1.397 33 0.481 34 0.463 35 0.757 36 1.670 37 1.487 38 1.551 39 1.332 40 1.238 41 1.535 42 2.270 43 2.427 44 2.810 45 2.805 46 2.719 47 2.428 48 1.978 49 1.818 50 1.528 51 1.226 52 1.600 53 1.165 54 1.286 55 1.009 56 1.072 57 1.906 58 1.995 59 2.406 60 2.035 61 1.362 62 1.133 63 0.559 64 0.323 65 0.239 66 0.151 67 -0.108 68 0.013 69 -0.034 70 -0.360 71 0.086 72 -0.373 73 -0.235 74 0.533 75 0.827 76 1.179 77 1.333 78 1.346 79 1.944 80 2.800 81 4.060 82 5.275 83 6.202 84 6.007 85 6.609 86 7.191 87 7.252 88 7.405 89 7.854 90 7.478 91 7.671 92 8.007 93 8.137 94 8.401 95 8.446 96 8.547 97 8.380 98 8.126 99 7.376 100 6.561 101 5.348 102 5.618 103 5.683 104 5.522 105 5.000 106 4.859 107 4.585 108 3.779 109 4.112 110 4.736 111 4.524 112 4.621 113 4.546 114 4.010 115 4.438 116 5.250 117 5.610 118 6.208 119 6.619 120 7.927 121 8.042 122 8.716 123 9.383 124 9.572 125 9.968 126 9.224 127 9.226 128 8.762 129 8.505 130 8.917 131 9.195 132 9.020 133 9.206 134 9.191 135 8.334 136 7.537 137 7.858 138 8.456 139 8.123 140 8.452 141 8.855 142 8.097 143 7.585 144 7.398 145 7.128 146 6.703 147 6.042 148 4.816 149 3.659 150 3.156 151 2.668 152 1.762 153 0.944 154 1.007 155 1.988 156 1.902 157 1.923 158 1.941 159 1.071 160 0.881 161 1.109 162 1.857 163 1.845 164 2.385 165 2.062 166 1.457 167 2.313 168 2.613 169 2.893 170 3.301 171 3.163 172 3.626 173 3.311 174 3.232 175 3.558 176 3.733 177 4.818 178 6.308 179 7.149 180 7.327 181 6.702 182 6.096 183 6.205 184 5.948 185 5.613 186 4.956 187 5.351 188 5.898 189 6.344 190 6.626 191 6.360 192 6.956 193 6.306 194 6.549 195 7.275 196 6.760 197 6.350 198 5.893 199 5.436 200 5.417 201 5.794 202 4.817 203 5.066 204 4.754 205 4.903 206 4.288 207 3.532 208 2.887 209 2.384 210 1.837 211 1.037 212 0.510 213 -0.169 214 -0.989 215 -0.752 216 -0.469 217 0.264 218 1.341 219 1.851 220 1.912 221 2.306 222 2.350 223 3.679 224 3.751 225 4.589 226 5.631 227 7.124 228 7.194 229 7.717 230 8.292 231 8.540 232 8.165 233 8.041 234 7.024 235 6.780 236 7.027 237 6.372 238 6.354 239 5.580 240 4.995 241 4.677 242 3.482 243 3.309 244 2.672 245 2.023 246 1.289 247 1.444 248 1.263 249 1.850 250 2.687 251 3.619 252 4.116 253 4.311 254 4.669 255 4.386 256 4.431 257 4.530 258 4.996 259 5.125 260 5.093 261 5.133 262 4.946 263 4.876 264 4.305 265 4.036 266 3.679 267 3.304 268 2.674 269 2.186 270 2.039 271 1.655 272 1.202 273 0.627 274 0.283 275 0.370 276 0.416 277 0.497 278 0.918 279 1.192 280 0.750 281 1.158 282 1.258 283 2.216 284 3.006 285 3.950 286 5.557 287 6.612 288 7.810 289 8.245 290 9.693 291 11.230 292 11.398 293 11.596 294 11.627 295 11.931 296 11.608 297 11.713 298 10.926 299 10.829 300 9.989 301 10.728 302 10.014 303 10.088 304 11.006 305 11.127 306 11.198 307 11.099 308 11.336 309 10.694 310 9.917 311 10.628 312 11.151 313 11.017 314 10.385 315 10.238 316 9.140 317 8.779 318 8.546 319 8.624 320 7.703 321 7.634 322 7.429 323 7.107 324 7.664 325 8.676 326 10.135 327 10.946 328 11.661 329 12.439 330 12.079 331 11.824 332 12.128 333 11.986 334 11.946 335 11.945 336 11.804 337 11.860 338 11.462 339 11.513 340 12.004 341 11.545 342 10.299 343 8.914 344 8.300 345 6.790 346 6.160 347 5.323 348 5.428 349 6.014 350 5.910 351 6.376 352 6.703 353 7.147 354 8.843 355 10.423 356 10.947 357 11.956 358 12.817 359 12.269 360 12.203 361 12.588 362 11.964 363 11.044 364 10.627 365 9.957 366 10.294 367 9.692 368 8.836 369 8.243 370 7.739 371 8.231 372 7.637 373 7.202 374 7.465 375 8.334 376 7.672 377 8.039 378 8.701 379 9.159 380 9.485 381 9.658 382 9.187 383 8.547 384 9.097 385 8.813 386 9.514 387 9.950 388 11.205 389 11.765 390 11.372 391 11.709 392 11.501 393 10.965 394 10.010 395 10.553 396 10.063 397 9.252 398 8.854 399 9.022 400 8.534 401 8.038 402 8.372 403 7.402 404 6.858 405 5.934 406 6.113 407 5.836 408 5.622 409 6.207 410 5.597 411 5.467 412 5.837 413 6.903 414 7.152 415 7.947 416 9.404 417 10.184 418 10.264 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 100.00 12 100.00 13 100.00 14 99.05 15 97.14 16 97.14 17 97.14 18 97.14 19 97.14 20 97.14 21 97.14 22 97.14 23 97.14 24 97.14 25 97.14 26 97.14 27 97.14 28 97.14 29 97.14 30 97.14 31 97.14 32 97.14 33 97.14 34 97.14 35 96.19 36 96.19 37 96.19 38 96.19 39 96.19 40 96.19 41 96.19 42 96.19 43 96.19 44 96.19 45 96.19 46 94.29 47 92.38 48 90.48 49 88.57 50 86.67 51 85.71 52 84.76 53 83.81 54 82.86 55 81.90 56 82.86 57 83.81 58 82.86 59 81.90 60 80.95 61 80.00 62 79.05 63 78.10 64 77.14 65 76.19 66 75.24 67 76.19 68 77.14 69 78.10 70 78.10 71 78.10 72 78.10 73 78.10 74 78.10 75 78.10 76 78.10 77 78.10 78 78.10 79 78.10 80 78.10 81 78.10 82 78.10 83 78.10 84 78.10 85 78.10 86 78.10 87 78.10 88 78.10 89 78.10 90 77.14 91 77.14 92 75.24 93 72.38 94 69.52 95 68.57 96 67.62 97 66.67 98 65.71 99 64.76 100 63.81 101 62.86 102 61.90 103 60.95 104 60.00 105 59.05 106 58.10 107 57.14 108 56.19 109 55.24 110 53.33 111 52.38 112 51.43 113 53.33 114 55.24 115 57.14 116 58.10 117 59.05 118 60.00 119 60.95 120 61.90 121 62.86 122 63.81 123 64.76 124 65.71 125 66.67 126 67.62 127 68.57 128 69.52 129 70.48 130 71.43 131 73.33 132 75.24 133 75.24 134 74.29 135 73.33 136 72.38 137 70.48 138 69.52 139 69.52 140 69.52 141 69.52 142 69.52 143 69.52 144 69.52 145 69.52 146 69.52 147 69.52 148 69.52 149 69.52 150 69.52 151 69.52 152 69.52 153 69.52 154 70.48 155 71.43 156 72.38 157 74.29 158 76.19 159 75.24 160 75.24 161 75.24 162 75.24 163 75.24 164 75.24 165 75.24 166 75.24 167 75.24 168 75.24 169 75.24 170 75.24 171 75.24 172 75.24 173 75.24 174 75.24 175 76.19 176 77.14 177 78.10 178 78.10 179 78.10 180 80.00 181 80.00 182 80.00 183 80.00 184 80.00 185 80.00 186 79.05 187 78.10 188 77.14 189 75.24 190 74.29 191 73.33 192 72.38 193 72.38 194 72.38 195 73.33 196 74.29 197 75.24 198 76.19 199 77.14 200 78.10 201 78.10 202 79.05 203 80.00 204 80.95 205 81.90 206 82.86 207 84.76 208 86.67 209 88.57 210 90.48 211 89.52 212 88.57 213 87.62 214 85.71 215 83.81 216 81.90 217 80.00 218 78.10 219 76.19 220 74.29 221 72.38 222 71.43 223 69.52 224 67.62 225 65.71 226 63.81 227 61.90 228 60.00 229 58.10 230 56.19 231 55.24 232 56.19 233 57.14 234 58.10 235 59.05 236 60.00 237 60.00 238 60.00 239 60.00 240 60.00 241 60.00 242 60.00 243 60.00 244 60.00 245 60.95 246 62.86 247 64.76 248 66.67 249 68.57 250 70.48 251 72.38 252 73.33 253 73.33 254 74.29 255 75.24 256 77.14 257 79.05 258 80.95 259 82.86 260 84.76 261 86.67 262 88.57 263 90.48 264 92.38 265 94.29 266 95.24 267 95.24 268 95.24 269 95.24 270 95.24 271 95.24 272 95.24 273 96.19 274 98.10 275 96.19 276 94.29 277 94.29 278 94.29 279 94.29 280 94.29 281 94.29 282 94.29 283 94.29 284 94.29 285 94.29 286 94.29 287 94.29 288 94.29 289 94.29 290 94.29 291 94.29 292 94.29 293 94.29 294 94.29 295 94.29 296 97.14 297 100.00 298 100.00 299 100.00 300 100.00 301 100.00 302 100.00 303 100.00 304 100.00 305 100.00 306 100.00 307 100.00 308 100.00 309 100.00 310 100.00 311 100.00 312 100.00 313 100.00 314 100.00 315 100.00 316 100.00 317 100.00 318 100.00 319 100.00 320 100.00 321 100.00 322 100.00 323 100.00 324 100.00 325 100.00 326 100.00 327 100.00 328 100.00 329 100.00 330 100.00 331 100.00 332 100.00 333 100.00 334 100.00 335 100.00 336 100.00 337 100.00 338 100.00 339 100.00 340 100.00 341 100.00 342 100.00 343 100.00 344 100.00 345 100.00 346 100.00 347 100.00 348 100.00 349 100.00 350 100.00 351 100.00 352 100.00 353 100.00 354 100.00 355 100.00 356 100.00 357 100.00 358 100.00 359 100.00 360 100.00 361 100.00 362 100.00 363 100.00 364 100.00 365 100.00 366 100.00 367 100.00 368 100.00 369 100.00 370 100.00 371 100.00 372 100.00 373 100.00 374 100.00 375 100.00 376 100.00 377 100.00 378 100.00 379 100.00 380 100.00 381 100.00 382 100.00 383 100.00 384 100.00 385 100.00 386 100.00 387 100.00 388 100.00 389 100.00 390 100.00 391 100.00 392 100.00 393 100.00 394 100.00 395 100.00 396 100.00 397 100.00 398 100.00 399 100.00 400 100.00 401 100.00 402 100.00 403 100.00 404 100.00 405 100.00 406 100.00 407 100.00 408 100.00 409 100.00 410 100.00 411 100.00 412 100.00 413 100.00 414 100.00 415 100.00 416 100.00 ##############################################################################