############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:24:25 Total request time: 41.1 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|O43826|G6PT1_HUMAN Glucose-6-phosphate exchanger SLC37A4 OS=Homo sapiens OX=9606 GN=SLC37A4 PE=1 SV=1 Sequence length: 429 aa. Sequence: MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE TOPCONS predicted topology: ooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii OCTOPUS predicted topology: oooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii Philius predicted topology: ooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii PolyPhobius predicted topology: iiiiiiiMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii SCAMPI predicted topology: oooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiii SPOCTOPUS predicted topology: oooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiii 4gc0A: --iiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMooo-ooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMM-MMiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMM-MMMMMMMMMiiiiiiiiiiiiiiiiiiii------iiiiiiiiiiiiiiiiiiiiiiiiiM-MMMMMMMMMMMMMMM-MMMMMMooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMMMMMMMMM--MiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMM--MMMMMMMMiiiiiiiiii----- Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 5.631 11 5.296 12 4.405 13 3.941 14 2.321 15 1.624 16 1.465 17 0.907 18 1.868 19 2.405 20 3.178 21 3.795 22 4.257 23 5.446 24 6.139 25 6.343 26 6.682 27 7.354 28 7.887 29 7.019 30 6.235 31 6.431 32 6.033 33 5.980 34 6.339 35 5.819 36 6.256 37 6.043 38 6.730 39 7.302 40 7.694 41 8.897 42 8.887 43 9.672 44 10.043 45 10.628 46 10.509 47 10.380 48 10.731 49 10.314 50 9.045 51 7.935 52 7.379 53 6.160 54 6.309 55 6.111 56 5.645 57 5.517 58 5.875 59 6.877 60 6.687 61 6.583 62 7.031 63 7.192 64 7.017 65 6.518 66 6.266 67 5.840 68 5.956 69 5.855 70 5.503 71 5.243 72 5.652 73 5.962 74 6.295 75 6.548 76 6.235 77 5.302 78 4.626 79 4.439 80 3.804 81 2.676 82 2.398 83 1.248 84 0.755 85 0.042 86 -0.024 87 -0.239 88 0.118 89 0.852 90 1.337 91 1.254 92 1.881 93 1.965 94 2.554 95 3.103 96 3.575 97 3.254 98 2.679 99 2.350 100 1.566 101 1.098 102 1.457 103 1.428 104 1.921 105 2.677 106 3.478 107 2.956 108 3.141 109 2.879 110 3.107 111 3.061 112 3.116 113 3.930 114 4.434 115 4.855 116 5.149 117 5.553 118 6.029 119 6.467 120 6.076 121 6.991 122 8.409 123 9.244 124 10.064 125 10.027 126 11.085 127 10.850 128 10.328 129 8.750 130 7.343 131 6.466 132 5.124 133 4.821 134 4.696 135 5.228 136 5.074 137 5.454 138 5.320 139 5.341 140 4.949 141 4.576 142 3.595 143 3.266 144 3.988 145 3.616 146 3.539 147 3.865 148 4.136 149 3.962 150 3.573 151 3.704 152 3.631 153 3.832 154 3.479 155 3.883 156 3.044 157 3.483 158 4.104 159 4.114 160 3.913 161 4.611 162 4.268 163 4.482 164 5.185 165 5.745 166 5.432 167 5.065 168 4.510 169 3.998 170 3.096 171 2.464 172 1.446 173 1.060 174 0.627 175 0.178 176 -0.397 177 -1.209 178 -1.491 179 -0.467 180 0.052 181 1.137 182 1.641 183 1.614 184 2.279 185 3.006 186 3.777 187 3.951 188 4.368 189 5.462 190 5.233 191 6.274 192 7.734 193 8.301 194 9.517 195 10.790 196 12.300 197 12.793 198 12.543 199 12.122 200 11.475 201 11.288 202 10.852 203 10.852 204 11.673 205 12.315 206 13.391 207 13.595 208 12.821 209 13.541 210 13.809 211 12.831 212 12.262 213 11.077 214 10.602 215 9.705 216 8.881 217 7.699 218 6.621 219 5.708 220 4.657 221 5.119 222 4.643 223 4.313 224 3.579 225 2.618 226 2.452 227 2.691 228 1.976 229 1.694 230 1.962 231 2.195 232 2.153 233 1.546 234 1.209 235 1.531 236 2.587 237 2.904 238 3.421 239 4.684 240 4.501 241 4.830 242 4.711 243 4.985 244 5.860 245 6.329 246 6.534 247 7.055 248 6.928 249 7.214 250 6.948 251 6.735 252 6.825 253 7.326 254 7.710 255 7.832 256 7.848 257 7.122 258 6.666 259 6.687 260 6.467 261 7.080 262 6.972 263 6.476 264 6.211 265 5.455 266 5.002 267 4.885 268 4.886 269 4.623 270 4.692 271 4.401 272 4.191 273 3.550 274 2.870 275 3.319 276 3.781 277 3.688 278 4.020 279 4.699 280 4.272 281 4.923 282 5.248 283 5.978 284 6.580 285 7.182 286 7.612 287 7.006 288 7.010 289 7.499 290 7.928 291 7.733 292 8.538 293 9.408 294 8.789 295 8.313 296 7.998 297 7.753 298 7.706 299 7.484 300 6.897 301 6.658 302 5.712 303 5.330 304 4.297 305 3.444 306 3.138 307 2.412 308 1.023 309 0.330 310 0.417 311 -0.036 312 -0.060 313 0.552 314 1.363 315 2.509 316 3.537 317 4.522 318 5.464 319 5.958 320 5.508 321 5.228 322 5.219 323 4.938 324 4.755 325 4.714 326 5.298 327 5.686 328 5.671 329 4.936 330 4.739 331 3.813 332 3.403 333 3.163 334 2.056 335 1.449 336 1.525 337 1.072 338 1.225 339 1.729 340 1.958 341 2.625 342 3.116 343 3.012 344 3.224 345 3.330 346 3.822 347 3.994 348 4.074 349 4.254 350 5.129 351 5.476 352 5.367 353 5.891 354 6.180 355 6.155 356 6.936 357 7.862 358 8.501 359 8.716 360 8.416 361 8.652 362 8.211 363 7.819 364 6.964 365 6.555 366 5.861 367 5.825 368 5.559 369 4.579 370 3.691 371 3.937 372 4.271 373 3.554 374 3.872 375 3.224 376 2.919 377 3.058 378 3.110 379 3.138 380 2.995 381 3.861 382 3.932 383 4.573 384 4.028 385 4.686 386 4.860 387 5.104 388 5.588 389 6.096 390 6.117 391 5.716 392 6.611 393 5.991 394 5.848 395 5.241 396 4.784 397 4.321 398 4.008 399 3.415 400 2.540 401 2.519 402 1.912 403 1.686 404 0.948 405 0.679 406 0.822 407 1.975 408 2.281 409 2.381 410 2.547 411 2.353 412 2.944 413 4.056 414 4.789 415 5.421 416 6.254 417 6.682 418 7.318 419 7.700 420 8.698 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 86.67 12 87.62 13 88.57 14 89.52 15 90.48 16 91.43 17 91.43 18 91.43 19 90.48 20 89.52 21 88.57 22 87.62 23 86.67 24 85.71 25 84.76 26 83.81 27 82.86 28 81.90 29 80.95 30 80.00 31 79.05 32 78.10 33 77.14 34 76.19 35 75.24 36 74.29 37 73.33 38 74.29 39 76.19 40 78.10 41 80.00 42 80.00 43 80.00 44 80.00 45 80.00 46 80.00 47 80.00 48 80.00 49 80.00 50 80.00 51 80.00 52 80.00 53 80.00 54 80.00 55 80.00 56 80.00 57 80.95 58 81.90 59 82.86 60 83.81 61 84.76 62 85.71 63 86.67 64 86.67 65 86.67 66 86.67 67 86.67 68 85.71 69 84.76 70 83.81 71 82.86 72 83.81 73 84.76 74 85.71 75 86.67 76 87.62 77 88.57 78 88.57 79 88.57 80 88.57 81 88.57 82 88.57 83 88.57 84 88.57 85 88.57 86 89.52 87 88.57 88 87.62 89 85.71 90 86.67 91 87.62 92 88.57 93 88.57 94 88.57 95 88.57 96 88.57 97 88.57 98 88.57 99 88.57 100 88.57 101 88.57 102 88.57 103 86.67 104 84.76 105 82.86 106 81.90 107 79.05 108 78.10 109 77.14 110 78.10 111 78.10 112 78.10 113 79.05 114 79.05 115 79.05 116 79.05 117 79.05 118 79.05 119 79.05 120 79.05 121 79.05 122 79.05 123 79.05 124 80.00 125 80.95 126 81.90 127 81.90 128 82.86 129 83.81 130 85.71 131 87.62 132 87.62 133 87.62 134 86.67 135 85.71 136 84.76 137 84.76 138 84.76 139 84.76 140 84.76 141 84.76 142 84.76 143 84.76 144 84.76 145 85.71 146 86.67 147 87.62 148 89.52 149 91.43 150 93.33 151 92.38 152 92.38 153 92.38 154 92.38 155 92.38 156 91.43 157 92.38 158 91.43 159 91.43 160 91.43 161 91.43 162 91.43 163 91.43 164 91.43 165 91.43 166 91.43 167 91.43 168 91.43 169 91.43 170 91.43 171 91.43 172 93.33 173 94.29 174 95.24 175 96.19 176 97.14 177 96.19 178 94.29 179 94.29 180 94.29 181 94.29 182 94.29 183 94.29 184 94.29 185 94.29 186 94.29 187 94.29 188 94.29 189 94.29 190 94.29 191 94.29 192 94.29 193 94.29 194 94.29 195 94.29 196 94.29 197 94.29 198 97.14 199 99.05 200 100.00 201 100.00 202 100.00 203 100.00 204 100.00 205 100.00 206 100.00 207 100.00 208 100.00 209 100.00 210 99.05 211 97.14 212 95.24 213 95.24 214 95.24 215 95.24 216 95.24 217 95.24 218 95.24 219 95.24 220 95.24 221 95.24 222 95.24 223 95.24 224 95.24 225 95.24 226 95.24 227 95.24 228 95.24 229 95.24 230 95.24 231 95.24 232 96.19 233 97.14 234 97.14 235 97.14 236 97.14 237 97.14 238 97.14 239 97.14 240 97.14 241 97.14 242 97.14 243 97.14 244 97.14 245 97.14 246 97.14 247 97.14 248 97.14 249 97.14 250 97.14 251 96.19 252 95.24 253 95.24 254 96.19 255 96.19 256 96.19 257 96.19 258 96.19 259 96.19 260 96.19 261 96.19 262 96.19 263 96.19 264 96.19 265 96.19 266 96.19 267 96.19 268 96.19 269 96.19 270 96.19 271 96.19 272 97.14 273 99.05 274 99.05 275 99.05 276 99.05 277 99.05 278 99.05 279 99.05 280 99.05 281 99.05 282 99.05 283 99.05 284 99.05 285 99.05 286 99.05 287 99.05 288 99.05 289 99.05 290 97.14 291 95.24 292 93.33 293 93.33 294 93.33 295 94.29 296 94.29 297 94.29 298 94.29 299 94.29 300 94.29 301 94.29 302 94.29 303 94.29 304 94.29 305 94.29 306 94.29 307 94.29 308 94.29 309 94.29 310 94.29 311 94.29 312 93.33 313 94.29 314 94.29 315 94.29 316 94.29 317 94.29 318 94.29 319 94.29 320 94.29 321 94.29 322 94.29 323 94.29 324 94.29 325 94.29 326 94.29 327 94.29 328 94.29 329 94.29 330 94.29 331 94.29 332 96.19 333 99.05 334 100.00 335 100.00 336 100.00 337 100.00 338 100.00 339 100.00 340 98.10 341 96.19 342 94.29 343 93.33 344 93.33 345 93.33 346 93.33 347 93.33 348 93.33 349 93.33 350 93.33 351 93.33 352 92.38 353 91.43 354 89.52 355 88.57 356 87.62 357 86.67 358 86.67 359 86.67 360 86.67 361 88.57 362 90.48 363 92.38 364 93.33 365 93.33 366 93.33 367 93.33 368 93.33 369 93.33 370 93.33 371 93.33 372 93.33 373 94.29 374 95.24 375 95.24 376 95.24 377 95.24 378 95.24 379 95.24 380 95.24 381 95.24 382 95.24 383 95.24 384 92.38 385 92.38 386 92.38 387 92.38 388 92.38 389 92.38 390 92.38 391 92.38 392 92.38 393 92.38 394 92.38 395 92.38 396 94.29 397 95.24 398 96.19 399 97.14 400 97.14 401 97.14 402 97.14 403 97.14 404 97.14 405 99.05 406 99.05 407 99.05 408 99.05 409 99.05 410 99.05 411 99.05 412 99.05 413 99.05 414 99.05 415 99.05 416 99.05 417 99.05 418 99.05 ##############################################################################