############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:34:53 Total request time: 6.5 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|P04156|PRIO_HUMAN Major prion protein OS=Homo sapiens OX=9606 GN=PRNP PE=1 SV=1 Sequence length: 253 aa. Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG TOPCONS predicted topology: SSSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMo OCTOPUS predicted topology: oMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMo Philius predicted topology: SSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMo PolyPhobius predicted topology: SSSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMo SCAMPI predicted topology: oMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoo SPOCTOPUS predicted topology: SSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMi 1skhA: -iiiMMMMMMMMMMMMMMMMMMoooooo--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 0.646 11 1.032 12 0.760 13 0.356 14 1.408 15 2.078 16 2.811 17 4.011 18 4.804 19 6.414 20 7.397 21 8.675 22 9.308 23 10.477 24 10.969 25 11.589 26 12.206 27 11.809 28 11.089 29 10.660 30 10.017 31 10.204 32 10.289 33 10.369 34 10.703 35 11.382 36 11.250 37 11.350 38 11.672 39 11.210 40 10.606 41 10.919 42 10.649 43 11.136 44 11.419 45 11.989 46 12.467 47 13.139 48 13.122 49 12.844 50 12.602 51 11.914 52 11.804 53 11.531 54 11.004 55 10.726 56 9.999 57 9.640 58 10.166 59 10.614 60 10.740 61 10.776 62 10.563 63 10.506 64 10.058 65 10.109 66 10.352 67 10.988 68 11.133 69 11.094 70 10.909 71 10.506 72 10.058 73 10.109 74 10.352 75 10.988 76 11.133 77 11.094 78 10.909 79 10.506 80 10.058 81 10.109 82 10.352 83 10.849 84 10.709 85 10.562 86 9.935 87 9.675 88 9.848 89 10.196 90 9.739 91 10.325 92 10.349 93 10.418 94 10.521 95 10.847 96 11.733 97 12.298 98 12.785 99 14.314 100 14.442 101 14.591 102 15.373 103 15.151 104 14.735 105 14.785 106 13.824 107 12.977 108 12.147 109 11.691 110 10.444 111 9.462 112 8.324 113 7.165 114 6.465 115 5.855 116 4.747 117 4.693 118 3.967 119 3.635 120 3.149 121 2.073 122 2.469 123 2.928 124 2.971 125 3.211 126 3.800 127 3.942 128 4.435 129 4.185 130 4.144 131 4.658 132 4.671 133 4.957 134 5.400 135 6.574 136 6.467 137 7.066 138 7.764 139 7.953 140 8.421 141 8.313 142 8.276 143 9.420 144 10.731 145 11.455 146 13.104 147 13.377 148 13.797 149 14.355 150 14.003 151 14.280 152 13.555 153 12.691 154 11.752 155 11.349 156 10.746 157 10.424 158 11.049 159 11.857 160 11.892 161 12.217 162 12.267 163 12.270 164 13.073 165 13.575 166 13.311 167 13.038 168 12.686 169 12.212 170 11.457 171 11.470 172 12.247 173 12.091 174 11.747 175 10.899 176 10.809 177 10.539 178 10.402 179 10.437 180 9.914 181 9.243 182 8.916 183 8.417 184 7.755 185 8.217 186 8.557 187 8.697 188 8.993 189 9.126 190 9.444 191 10.037 192 10.401 193 10.747 194 10.786 195 10.819 196 10.230 197 9.735 198 10.581 199 10.708 200 10.699 201 10.607 202 11.297 203 11.716 204 11.517 205 11.308 206 10.438 207 9.524 208 9.742 209 9.009 210 8.319 211 7.780 212 7.790 213 8.260 214 8.688 215 9.126 216 9.418 217 9.179 218 10.179 219 10.617 220 11.165 221 11.268 222 11.205 223 11.132 224 10.935 225 10.340 226 9.781 227 9.273 228 9.296 229 8.551 230 8.231 231 6.833 232 5.781 233 4.375 234 3.889 235 3.737 236 4.042 237 2.985 238 2.524 239 1.951 240 1.040 241 0.029 242 -0.262 243 -0.513 244 -0.001 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 56.19 12 54.29 13 54.29 14 54.29 15 54.29 16 54.29 17 54.29 18 54.29 19 54.29 20 54.29 21 54.29 22 54.29 23 54.29 24 54.29 25 54.29 26 54.29 27 54.29 28 54.29 29 55.24 30 56.19 31 57.14 32 58.10 33 60.00 34 60.00 35 60.00 36 60.00 37 60.00 38 60.00 39 60.00 40 60.00 41 60.00 42 60.00 43 60.00 44 60.00 45 60.00 46 60.00 47 60.00 48 60.00 49 60.00 50 60.00 51 60.00 52 60.00 53 60.00 54 60.00 55 60.00 56 60.00 57 60.00 58 60.00 59 60.00 60 60.00 61 60.00 62 60.00 63 60.00 64 60.00 65 60.00 66 60.00 67 60.00 68 60.00 69 60.00 70 60.00 71 60.00 72 60.00 73 60.00 74 60.00 75 60.00 76 60.00 77 60.00 78 60.00 79 60.00 80 60.00 81 60.00 82 60.00 83 60.00 84 60.00 85 60.00 86 60.00 87 60.00 88 60.00 89 60.00 90 60.00 91 60.00 92 60.00 93 60.00 94 60.00 95 60.00 96 60.00 97 60.00 98 60.00 99 60.00 100 60.00 101 58.10 102 57.14 103 56.19 104 55.24 105 54.29 106 53.33 107 52.38 108 51.43 109 50.48 110 49.52 111 48.57 112 47.62 113 46.67 114 45.71 115 44.76 116 43.81 117 42.86 118 41.90 119 40.95 120 40.00 121 39.05 122 41.90 123 43.81 124 45.71 125 47.62 126 49.52 127 51.43 128 53.33 129 55.24 130 57.14 131 59.05 132 60.95 133 62.86 134 64.76 135 66.67 136 68.57 137 70.48 138 72.38 139 74.29 140 76.19 141 78.10 142 80.00 143 80.00 144 80.00 145 80.00 146 80.00 147 80.00 148 80.00 149 80.00 150 80.00 151 80.00 152 80.00 153 80.00 154 80.00 155 80.00 156 80.00 157 80.00 158 80.00 159 80.00 160 80.00 161 80.00 162 80.00 163 80.00 164 80.00 165 80.00 166 80.00 167 80.00 168 80.00 169 80.00 170 80.00 171 80.00 172 80.00 173 80.00 174 80.00 175 80.00 176 80.00 177 80.00 178 80.00 179 80.00 180 80.00 181 80.00 182 80.00 183 80.00 184 80.00 185 80.00 186 80.00 187 80.00 188 80.00 189 80.00 190 80.00 191 80.00 192 80.00 193 80.00 194 80.00 195 80.00 196 80.00 197 80.00 198 80.00 199 80.00 200 80.00 201 80.00 202 80.00 203 80.00 204 80.00 205 80.00 206 80.00 207 80.00 208 80.00 209 80.00 210 80.00 211 80.00 212 80.00 213 80.00 214 80.00 215 80.00 216 80.00 217 80.00 218 80.00 219 80.00 220 79.05 221 76.19 222 77.14 223 78.10 224 79.05 225 80.00 226 80.95 227 81.90 228 82.86 229 83.81 230 84.76 231 85.71 232 86.67 233 87.62 234 88.57 235 89.52 236 90.48 237 91.43 238 92.38 239 93.33 240 94.29 241 96.19 242 99.05 ##############################################################################