############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:22:58 Total request time: 14.1 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|P61619|S61A1_HUMAN Protein transport protein Sec61 subunit alpha isoform 1 OS=Homo sapiens OX=9606 GN=SEC61A1 PE=1 SV=2 Sequence length: 476 aa. Sequence: MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF TOPCONS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii OCTOPUS predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii Philius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii PolyPhobius predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii SCAMPI predicted topology: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii SPOCTOPUS predicted topology: SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiii 2wwbA: iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMooooooooooooooooMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMooMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiii Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 5.445 11 5.733 12 5.929 13 6.456 14 6.760 15 7.226 16 8.304 17 8.007 18 9.100 19 9.567 20 10.285 21 11.192 22 12.504 23 13.136 24 13.152 25 12.898 26 12.693 27 11.447 28 10.160 29 9.698 30 8.290 31 7.412 32 6.437 33 4.839 34 3.961 35 3.100 36 2.426 37 1.017 38 0.887 39 -0.052 40 -0.467 41 -1.296 42 -1.458 43 -0.783 44 -0.598 45 -0.547 46 0.007 47 0.798 48 1.388 49 2.323 50 2.894 51 3.763 52 4.898 53 5.563 54 5.935 55 5.997 56 6.216 57 6.127 58 6.614 59 6.398 60 6.837 61 7.135 62 7.185 63 7.617 64 7.277 65 6.914 66 5.976 67 4.753 68 3.934 69 4.302 70 3.506 71 3.769 72 4.338 73 5.081 74 5.755 75 5.623 76 5.403 77 5.154 78 5.239 79 5.500 80 4.803 81 4.049 82 3.190 83 3.556 84 2.731 85 2.371 86 2.662 87 3.080 88 2.470 89 3.130 90 2.834 91 2.960 92 3.377 93 3.227 94 3.907 95 4.448 96 4.743 97 5.118 98 5.304 99 6.398 100 7.010 101 7.533 102 7.367 103 8.061 104 9.504 105 10.292 106 10.411 107 11.162 108 11.212 109 11.037 110 10.535 111 9.878 112 9.322 113 8.324 114 7.392 115 6.896 116 5.815 117 5.439 118 5.412 119 5.535 120 5.147 121 5.045 122 4.764 123 3.610 124 3.072 125 2.996 126 2.880 127 2.794 128 3.145 129 3.777 130 3.872 131 4.493 132 5.366 133 6.745 134 7.162 135 7.774 136 7.661 137 7.599 138 7.253 139 7.445 140 7.026 141 6.460 142 5.921 143 5.396 144 4.693 145 4.250 146 3.602 147 2.945 148 2.203 149 1.484 150 1.327 151 0.610 152 0.116 153 0.156 154 -0.526 155 -0.891 156 -1.650 157 -1.140 158 -0.526 159 -0.291 160 -0.211 161 0.773 162 1.413 163 2.296 164 2.438 165 3.757 166 4.328 167 5.120 168 6.046 169 6.435 170 6.991 171 7.387 172 6.734 173 6.537 174 6.215 175 5.813 176 4.716 177 3.856 178 3.524 179 3.368 180 3.222 181 3.070 182 3.012 183 3.285 184 2.799 185 3.460 186 3.321 187 2.977 188 3.451 189 4.441 190 4.624 191 5.326 192 5.910 193 6.719 194 6.890 195 7.299 196 6.665 197 6.987 198 6.843 199 7.015 200 6.787 201 7.694 202 8.299 203 8.757 204 8.485 205 8.314 206 8.129 207 6.716 208 5.365 209 5.504 210 4.703 211 4.088 212 3.388 213 3.178 214 2.655 215 2.587 216 2.864 217 3.459 218 3.340 219 4.282 220 4.577 221 4.797 222 5.650 223 7.179 224 7.855 225 7.979 226 8.266 227 8.447 228 8.061 229 8.845 230 8.699 231 8.995 232 9.246 233 8.714 234 8.544 235 8.758 236 8.224 237 8.036 238 7.709 239 7.236 240 6.990 241 6.145 242 5.109 243 4.413 244 4.367 245 4.032 246 3.571 247 2.429 248 1.406 249 0.847 250 0.479 251 -0.117 252 -0.080 253 -0.002 254 -0.462 255 0.754 256 1.132 257 2.213 258 2.777 259 3.751 260 4.900 261 5.403 262 5.962 263 5.899 264 5.790 265 6.143 266 7.169 267 7.701 268 8.875 269 9.090 270 9.121 271 10.019 272 10.051 273 10.343 274 9.520 275 9.292 276 8.269 277 7.739 278 7.297 279 7.279 280 7.194 281 7.654 282 7.527 283 7.053 284 5.780 285 5.350 286 5.591 287 4.788 288 4.266 289 4.073 290 3.566 291 3.917 292 3.274 293 3.542 294 3.756 295 3.636 296 3.982 297 4.334 298 3.933 299 4.039 300 4.337 301 4.607 302 4.736 303 4.706 304 4.692 305 4.647 306 5.149 307 5.173 308 4.852 309 4.636 310 4.532 311 4.850 312 4.516 313 4.627 314 4.321 315 3.295 316 2.835 317 3.071 318 3.574 319 3.833 320 4.715 321 5.577 322 6.570 323 7.128 324 7.171 325 6.705 326 7.199 327 7.314 328 7.657 329 7.150 330 7.769 331 8.677 332 8.184 333 8.296 334 8.177 335 7.174 336 5.858 337 5.778 338 5.796 339 5.808 340 6.150 341 6.450 342 5.779 343 6.188 344 6.773 345 7.011 346 6.851 347 7.033 348 7.438 349 7.407 350 7.233 351 8.485 352 8.829 353 9.152 354 9.294 355 9.480 356 8.708 357 8.064 358 7.149 359 6.171 360 5.255 361 5.380 362 5.098 363 4.240 364 3.854 365 3.419 366 2.032 367 1.618 368 1.442 369 1.500 370 0.848 371 1.000 372 2.225 373 2.843 374 3.804 375 4.822 376 5.677 377 6.553 378 6.698 379 7.332 380 7.297 381 6.978 382 7.041 383 7.482 384 8.557 385 8.971 386 9.542 387 10.770 388 11.936 389 13.134 390 13.635 391 13.125 392 13.203 393 12.794 394 12.522 395 12.158 396 11.277 397 11.440 398 10.763 399 10.423 400 10.447 401 10.518 402 10.820 403 11.357 404 11.429 405 11.438 406 10.590 407 9.451 408 8.498 409 8.782 410 8.818 411 9.045 412 9.383 413 9.430 414 8.661 415 8.894 416 8.563 417 7.678 418 6.657 419 5.854 420 5.470 421 4.039 422 2.653 423 2.952 424 2.005 425 1.621 426 1.557 427 2.048 428 1.366 429 1.245 430 1.819 431 2.046 432 2.177 433 2.876 434 3.255 435 3.421 436 3.984 437 4.436 438 4.397 439 3.599 440 3.067 441 3.138 442 2.445 443 2.248 444 2.173 445 1.779 446 1.039 447 1.529 448 1.695 449 1.080 450 1.962 451 2.340 452 2.223 453 2.378 454 2.786 455 3.778 456 4.315 457 5.241 458 6.810 459 7.565 460 8.020 461 8.579 462 8.646 463 9.064 464 9.207 465 8.750 466 7.648 467 7.125 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 80.00 12 80.00 13 80.00 14 80.00 15 80.00 16 80.00 17 80.00 18 80.00 19 80.00 20 80.00 21 80.00 22 79.05 23 79.05 24 79.05 25 79.05 26 79.05 27 79.05 28 79.05 29 79.05 30 79.05 31 79.05 32 79.05 33 79.05 34 79.05 35 79.05 36 79.05 37 79.05 38 79.05 39 79.05 40 79.05 41 79.05 42 79.05 43 78.10 44 77.14 45 78.10 46 79.05 47 80.00 48 80.95 49 81.90 50 82.86 51 83.81 52 84.76 53 85.71 54 86.67 55 87.62 56 88.57 57 89.52 58 90.48 59 91.43 60 92.38 61 93.33 62 94.29 63 95.24 64 98.10 65 98.10 66 96.19 67 94.29 68 92.38 69 90.48 70 88.57 71 86.67 72 84.76 73 82.86 74 80.95 75 79.05 76 77.14 77 75.24 78 73.33 79 71.43 80 69.52 81 67.62 82 65.71 83 63.81 84 61.90 85 60.00 86 59.05 87 57.14 88 57.14 89 57.14 90 57.14 91 57.14 92 57.14 93 57.14 94 57.14 95 57.14 96 57.14 97 57.14 98 57.14 99 57.14 100 57.14 101 57.14 102 57.14 103 57.14 104 57.14 105 56.19 106 56.19 107 57.14 108 60.95 109 62.86 110 64.76 111 66.67 112 68.57 113 70.48 114 72.38 115 74.29 116 76.19 117 78.10 118 80.00 119 81.90 120 83.81 121 85.71 122 87.62 123 89.52 124 91.43 125 93.33 126 95.24 127 93.33 128 92.38 129 90.48 130 88.57 131 86.67 132 84.76 133 80.95 134 77.14 135 77.14 136 77.14 137 77.14 138 77.14 139 77.14 140 77.14 141 77.14 142 77.14 143 77.14 144 77.14 145 77.14 146 77.14 147 78.10 148 81.90 149 84.76 150 86.67 151 88.57 152 90.48 153 92.38 154 95.24 155 97.14 156 95.24 157 93.33 158 91.43 159 89.52 160 87.62 161 85.71 162 83.81 163 81.90 164 80.00 165 78.10 166 76.19 167 74.29 168 72.38 169 70.48 170 68.57 171 66.67 172 64.76 173 62.86 174 60.95 175 60.00 176 60.00 177 60.00 178 60.00 179 60.00 180 60.00 181 60.00 182 60.00 183 60.00 184 61.90 185 63.81 186 65.71 187 67.62 188 69.52 189 71.43 190 73.33 191 75.24 192 77.14 193 79.05 194 80.00 195 80.95 196 81.90 197 82.86 198 83.81 199 84.76 200 85.71 201 86.67 202 87.62 203 88.57 204 89.52 205 88.57 206 87.62 207 86.67 208 85.71 209 84.76 210 83.81 211 82.86 212 81.90 213 80.95 214 80.00 215 80.00 216 80.00 217 80.00 218 80.00 219 80.00 220 80.00 221 80.00 222 80.00 223 80.00 224 80.00 225 80.00 226 80.00 227 80.00 228 80.00 229 80.00 230 80.00 231 79.05 232 80.00 233 80.95 234 81.90 235 82.86 236 83.81 237 84.76 238 85.71 239 86.67 240 87.62 241 88.57 242 89.52 243 90.48 244 91.43 245 92.38 246 93.33 247 94.29 248 95.24 249 96.19 250 97.14 251 98.10 252 98.10 253 96.19 254 95.24 255 94.29 256 93.33 257 92.38 258 91.43 259 90.48 260 89.52 261 88.57 262 87.62 263 86.67 264 85.71 265 84.76 266 83.81 267 82.86 268 81.90 269 80.95 270 80.00 271 79.05 272 78.10 273 77.14 274 79.05 275 80.00 276 80.95 277 81.90 278 82.86 279 83.81 280 84.76 281 85.71 282 86.67 283 87.62 284 88.57 285 89.52 286 90.48 287 91.43 288 92.38 289 93.33 290 94.29 291 95.24 292 96.19 293 97.14 294 99.05 295 97.14 296 96.19 297 95.24 298 94.29 299 93.33 300 92.38 301 91.43 302 90.48 303 89.52 304 88.57 305 87.62 306 86.67 307 85.71 308 84.76 309 83.81 310 82.86 311 81.90 312 80.95 313 80.00 314 79.05 315 79.05 316 80.00 317 80.00 318 80.00 319 80.00 320 80.00 321 80.95 322 81.90 323 82.86 324 83.81 325 84.76 326 85.71 327 86.67 328 87.62 329 88.57 330 89.52 331 90.48 332 91.43 333 92.38 334 93.33 335 94.29 336 95.24 337 96.19 338 97.14 339 98.10 340 99.05 341 100.00 342 100.00 343 100.00 344 100.00 345 100.00 346 100.00 347 100.00 348 99.05 349 97.14 350 97.14 351 97.14 352 97.14 353 97.14 354 97.14 355 97.14 356 97.14 357 97.14 358 97.14 359 97.14 360 97.14 361 97.14 362 97.14 363 97.14 364 97.14 365 97.14 366 97.14 367 97.14 368 97.14 369 97.14 370 96.19 371 96.19 372 96.19 373 96.19 374 96.19 375 96.19 376 96.19 377 96.19 378 96.19 379 96.19 380 96.19 381 96.19 382 96.19 383 96.19 384 96.19 385 96.19 386 96.19 387 96.19 388 96.19 389 96.19 390 97.14 391 100.00 392 100.00 393 100.00 394 100.00 395 100.00 396 100.00 397 100.00 398 100.00 399 100.00 400 100.00 401 100.00 402 100.00 403 99.05 404 98.10 405 96.19 406 96.19 407 96.19 408 96.19 409 96.19 410 96.19 411 96.19 412 96.19 413 96.19 414 96.19 415 96.19 416 96.19 417 96.19 418 96.19 419 96.19 420 96.19 421 96.19 422 96.19 423 96.19 424 97.14 425 96.19 426 96.19 427 96.19 428 94.29 429 93.33 430 93.33 431 93.33 432 93.33 433 93.33 434 93.33 435 93.33 436 93.33 437 93.33 438 93.33 439 93.33 440 93.33 441 93.33 442 93.33 443 93.33 444 93.33 445 93.33 446 95.24 447 97.14 448 97.14 449 99.05 450 100.00 451 100.00 452 100.00 453 100.00 454 100.00 455 100.00 456 100.00 457 100.00 458 100.00 459 100.00 460 100.00 461 100.00 462 100.00 463 100.00 464 100.00 465 100.00 ##############################################################################