############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:51:21 Total request time: 24.5 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|Q8NBQ5|DHB11_HUMAN Estradiol 17-beta-dehydrogenase 11 OS=Homo sapiens GN=HSD17B11 PE=1 SV=3 Sequence length: 300 aa. Sequence: MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKISVKFDAVIGYKMKAQ TOPCONS predicted topology: ooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo OCTOPUS predicted topology: ooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo Philius predicted topology: SSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo PolyPhobius predicted topology: iiMMMMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo SCAMPI predicted topology: ooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SPOCTOPUS predicted topology: ooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo Homology: No homologous hits found Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 -0.796 11 -0.282 12 -0.381 13 -0.341 14 -0.135 15 0.580 16 0.062 17 0.321 18 0.891 19 2.225 20 3.271 21 3.967 22 4.026 23 5.204 24 6.444 25 7.147 26 7.868 27 8.922 28 9.735 29 10.474 30 10.171 31 9.296 32 8.991 33 8.162 34 7.329 35 6.783 36 6.284 37 6.141 38 5.415 39 4.643 40 4.701 41 4.617 42 4.012 43 3.874 44 4.060 45 4.115 46 4.485 47 4.194 48 4.854 49 5.662 50 6.237 51 6.869 52 7.442 53 7.416 54 7.319 55 7.291 56 6.520 57 6.107 58 6.466 59 6.015 60 6.591 61 7.260 62 7.759 63 8.193 64 7.791 65 7.821 66 8.926 67 9.082 68 8.992 69 9.331 70 9.117 71 8.709 72 8.786 73 9.655 74 9.495 75 10.135 76 10.288 77 10.101 78 10.193 79 10.243 80 9.980 81 8.931 82 8.499 83 8.487 84 7.897 85 6.974 86 7.113 87 7.699 88 7.582 89 7.729 90 8.186 91 7.932 92 7.717 93 8.582 94 9.136 95 9.595 96 10.024 97 10.761 98 10.360 99 10.791 100 11.198 101 12.037 102 12.084 103 12.180 104 12.670 105 12.149 106 11.739 107 11.291 108 9.730 109 8.933 110 9.178 111 9.463 112 8.476 113 7.891 114 7.369 115 6.639 116 5.998 117 5.725 118 5.711 119 6.014 120 5.308 121 5.170 122 4.852 123 4.570 124 5.358 125 5.748 126 6.786 127 8.072 128 8.332 129 8.859 130 8.759 131 9.057 132 8.860 133 9.987 134 10.330 135 11.031 136 11.080 137 10.228 138 9.631 139 10.148 140 9.603 141 8.665 142 7.807 143 6.704 144 6.054 145 5.552 146 4.973 147 4.839 148 4.805 149 4.839 150 5.012 151 5.359 152 5.131 153 5.776 154 5.698 155 6.533 156 7.438 157 8.077 158 7.888 159 8.438 160 8.815 161 8.713 162 8.511 163 8.453 164 8.154 165 8.021 166 8.105 167 7.991 168 7.620 169 7.564 170 7.279 171 7.380 172 6.452 173 5.666 174 4.643 175 4.129 176 3.278 177 3.124 178 3.428 179 3.756 180 4.150 181 4.133 182 4.090 183 4.315 184 4.459 185 4.616 186 3.927 187 4.744 188 4.640 189 4.707 190 3.938 191 4.157 192 4.991 193 6.148 194 6.338 195 6.899 196 7.321 197 6.968 198 7.398 199 7.147 200 7.422 201 7.377 202 6.946 203 6.785 204 6.014 205 5.882 206 5.173 207 4.361 208 4.289 209 4.917 210 5.653 211 5.071 212 4.729 213 5.957 214 6.091 215 6.324 216 6.203 217 5.410 218 5.579 219 5.903 220 6.184 221 6.695 222 6.658 223 7.264 224 7.032 225 7.486 226 8.551 227 8.715 228 8.108 229 8.458 230 9.324 231 9.844 232 10.047 233 10.065 234 9.640 235 10.245 236 10.195 237 9.317 238 8.586 239 8.977 240 9.015 241 9.055 242 8.586 243 9.063 244 9.293 245 9.241 246 9.402 247 9.561 248 8.471 249 7.632 250 6.700 251 6.252 252 6.544 253 6.953 254 6.125 255 5.979 256 5.756 257 5.023 258 4.315 259 3.750 260 3.291 261 3.868 262 3.729 263 2.844 264 2.306 265 2.984 266 4.246 267 4.947 268 5.452 269 5.526 270 5.309 271 5.169 272 4.571 273 4.911 274 5.272 275 5.745 276 5.966 277 6.420 278 6.395 279 6.910 280 6.207 281 6.820 282 7.172 283 7.647 284 7.297 285 7.064 286 6.886 287 7.083 288 7.104 289 7.232 290 7.176 291 7.822 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 78.10 12 79.05 13 80.00 14 79.05 15 78.10 16 77.14 17 76.19 18 75.24 19 74.29 20 73.33 21 72.38 22 71.43 23 70.48 24 69.52 25 68.57 26 66.67 27 64.76 28 62.86 29 60.95 30 59.05 31 57.14 32 55.24 33 53.33 34 51.43 35 50.48 36 49.52 37 48.57 38 47.62 39 46.67 40 45.71 41 44.76 42 43.81 43 42.86 44 41.90 45 40.95 46 40.00 47 41.90 48 43.81 49 45.71 50 47.62 51 49.52 52 51.43 53 53.33 54 55.24 55 57.14 56 59.05 57 60.95 58 62.86 59 64.76 60 66.67 61 68.57 62 70.48 63 72.38 64 74.29 65 76.19 66 78.10 67 80.00 68 80.00 69 80.00 70 80.00 71 80.00 72 80.00 73 80.00 74 80.00 75 80.00 76 80.00 77 80.00 78 80.00 79 80.00 80 80.00 81 80.00 82 80.00 83 80.00 84 80.00 85 80.00 86 80.00 87 80.00 88 80.00 89 80.00 90 80.00 91 80.00 92 80.00 93 80.00 94 80.00 95 80.00 96 80.00 97 80.00 98 80.00 99 80.00 100 80.00 101 80.00 102 80.00 103 80.00 104 80.00 105 80.00 106 80.00 107 80.00 108 80.00 109 80.00 110 80.00 111 80.00 112 80.00 113 80.00 114 80.00 115 80.00 116 80.00 117 80.00 118 80.00 119 80.00 120 80.00 121 80.00 122 80.00 123 80.00 124 80.00 125 80.00 126 80.00 127 80.00 128 80.00 129 80.00 130 80.00 131 80.00 132 80.00 133 80.00 134 80.00 135 80.00 136 80.00 137 80.00 138 80.00 139 80.00 140 80.00 141 80.00 142 80.00 143 80.00 144 80.00 145 80.00 146 80.00 147 80.00 148 80.00 149 80.00 150 80.00 151 80.00 152 80.00 153 80.00 154 80.00 155 80.00 156 80.00 157 80.00 158 80.00 159 80.00 160 80.00 161 80.00 162 80.00 163 80.00 164 80.00 165 80.00 166 80.00 167 80.00 168 80.00 169 80.00 170 80.00 171 80.00 172 80.00 173 80.00 174 80.00 175 80.00 176 80.00 177 80.00 178 80.00 179 80.00 180 80.00 181 80.00 182 80.00 183 80.00 184 80.00 185 80.00 186 80.00 187 80.00 188 80.00 189 80.00 190 80.00 191 80.00 192 80.00 193 80.00 194 80.00 195 80.00 196 80.00 197 80.00 198 80.00 199 80.00 200 80.00 201 80.00 202 80.00 203 80.00 204 80.00 205 80.00 206 80.00 207 80.00 208 80.00 209 80.00 210 80.00 211 80.00 212 80.00 213 80.00 214 80.00 215 80.00 216 80.00 217 80.00 218 80.00 219 80.00 220 80.00 221 80.00 222 80.00 223 80.00 224 80.00 225 80.00 226 80.00 227 80.00 228 80.00 229 80.00 230 80.00 231 80.00 232 80.00 233 80.00 234 80.00 235 80.00 236 80.00 237 80.00 238 80.00 239 80.00 240 80.00 241 80.00 242 80.00 243 80.00 244 80.00 245 80.00 246 80.00 247 80.00 248 80.00 249 80.00 250 80.00 251 80.00 252 80.00 253 80.00 254 80.00 255 80.00 256 80.00 257 80.00 258 80.00 259 80.00 260 80.00 261 80.00 262 80.00 263 80.00 264 80.00 265 80.00 266 80.00 267 80.00 268 80.00 269 80.00 270 80.00 271 80.00 272 80.00 273 80.00 274 80.00 275 80.00 276 80.00 277 80.00 278 80.00 279 80.00 280 80.00 281 80.00 282 80.00 283 80.00 284 80.00 285 80.00 286 80.00 287 80.00 288 80.00 289 80.00 ##############################################################################