############################################################################## TOPCONS2 result file Generated from http://commonbackend.computenode.pcons3.se at 2018-10-26 16:23:30 Total request time: 14.6 seconds. ############################################################################## Sequence number: 1 Sequence name: sp|Q8TCT8|SPP2A_HUMAN Signal peptide peptidase-like 2A OS=Homo sapiens OX=9606 GN=SPPL2A PE=1 SV=2 Sequence length: 520 aa. Sequence: MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWTALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDCATNEENPVISGEQIVQQ TOPCONS predicted topology: SSSSSSSSSSSSSSSSSSSSSSSSSoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii OCTOPUS predicted topology: ooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Philius predicted topology: SSSSSSSSSSSSSSSSSSSSSSSSSooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMiiiiiiiMMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii PolyPhobius predicted topology: oooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMMMMoooooMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SCAMPI predicted topology: iiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii SPOCTOPUS predicted topology: SSSSSSSSSSSSSSSSSSSSSSSSSoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMoMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooooooooooooooooooooooooooooooooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiMMMMMMMMMMMMMMMMMMMMMooooooMMMMMMMMMMMMMMMMMMMMMiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Homology: No homologous hits found Predicted Delta-G-values (kcal/mol) (left column=sequence position; right column=Delta-G) 10 4.247 11 3.149 12 2.812 13 1.908 14 1.501 15 1.479 16 1.453 17 2.134 18 2.690 19 2.369 20 2.431 21 1.979 22 2.842 23 3.069 24 3.927 25 4.774 26 5.823 27 5.781 28 6.057 29 6.409 30 7.137 31 7.097 32 7.532 33 7.755 34 8.081 35 8.215 36 8.157 37 8.643 38 9.433 39 9.650 40 9.580 41 8.767 42 8.445 43 7.548 44 7.585 45 7.248 46 6.788 47 6.311 48 6.935 49 7.229 50 6.931 51 7.001 52 7.319 53 7.051 54 7.415 55 6.835 56 6.041 57 6.021 58 5.841 59 5.908 60 6.064 61 5.861 62 6.325 63 5.334 64 4.813 65 5.271 66 5.502 67 5.499 68 5.676 69 5.857 70 6.367 71 6.816 72 7.080 73 7.018 74 7.247 75 7.587 76 7.300 77 7.973 78 8.067 79 7.752 80 7.756 81 7.449 82 8.385 83 8.179 84 7.756 85 8.268 86 7.530 87 7.341 88 6.801 89 5.644 90 6.005 91 6.375 92 6.170 93 6.356 94 6.091 95 5.757 96 6.018 97 6.590 98 7.401 99 8.182 100 8.779 101 9.729 102 10.338 103 10.083 104 9.145 105 8.693 106 7.498 107 7.743 108 8.370 109 7.537 110 7.071 111 6.365 112 5.716 113 5.805 114 5.918 115 5.813 116 5.937 117 6.255 118 6.187 119 6.782 120 7.374 121 7.550 122 8.329 123 9.454 124 9.929 125 10.591 126 10.367 127 9.769 128 9.373 129 9.176 130 8.957 131 8.546 132 7.970 133 6.797 134 5.990 135 5.663 136 4.695 137 4.667 138 4.751 139 4.434 140 5.786 141 6.706 142 7.265 143 8.011 144 9.004 145 10.187 146 11.432 147 11.389 148 11.060 149 10.862 150 10.674 151 9.966 152 9.442 153 9.016 154 8.655 155 9.059 156 8.636 157 8.494 158 9.077 159 8.435 160 8.731 161 8.841 162 9.344 163 9.083 164 8.786 165 8.149 166 8.168 167 7.712 168 7.357 169 6.475 170 5.891 171 5.144 172 3.572 173 2.238 174 1.260 175 0.789 176 -0.542 177 -0.891 178 -0.280 179 -0.664 180 -0.704 181 -0.199 182 0.393 183 0.559 184 1.051 185 2.471 186 2.955 187 3.828 188 4.946 189 4.825 190 5.201 191 5.522 192 5.513 193 5.510 194 5.512 195 6.722 196 7.133 197 7.363 198 8.680 199 9.324 200 9.255 201 9.646 202 10.811 203 11.584 204 12.402 205 14.337 206 14.204 207 13.946 208 14.539 209 13.983 210 14.032 211 14.074 212 13.016 213 12.243 214 10.707 215 9.560 216 8.541 217 6.837 218 5.990 219 5.073 220 3.826 221 2.779 222 1.773 223 0.430 224 -0.375 225 -0.575 226 -0.416 227 -0.951 228 -1.352 229 -1.986 230 -2.870 231 -2.733 232 -2.715 233 -2.126 234 -1.805 235 -1.449 236 -0.565 237 0.062 238 0.693 239 1.337 240 1.685 241 1.977 242 1.922 243 1.366 244 0.850 245 0.126 246 -0.199 247 -0.116 248 -0.512 249 -0.613 250 -0.295 251 -0.767 252 -1.128 253 -0.244 254 0.467 255 0.641 256 1.160 257 1.603 258 1.667 259 1.931 260 2.842 261 3.445 262 3.837 263 4.444 264 4.526 265 4.747 266 4.878 267 5.093 268 5.470 269 5.389 270 6.009 271 6.198 272 5.478 273 5.657 274 6.139 275 6.808 276 6.853 277 7.824 278 8.066 279 7.594 280 7.369 281 7.566 282 6.877 283 6.623 284 6.492 285 6.131 286 5.531 287 5.166 288 4.703 289 4.171 290 3.569 291 2.943 292 2.015 293 1.214 294 0.222 295 -0.079 296 -1.019 297 -1.244 298 -1.197 299 0.051 300 1.031 301 1.999 302 2.929 303 3.070 304 3.684 305 4.587 306 5.173 307 5.566 308 6.538 309 7.492 310 7.791 311 7.685 312 7.995 313 7.735 314 7.084 315 6.063 316 5.512 317 4.356 318 3.655 319 2.085 320 1.178 321 1.240 322 1.420 323 1.095 324 1.617 325 1.527 326 2.788 327 3.336 328 3.419 329 4.500 330 5.775 331 6.020 332 6.406 333 6.389 334 6.279 335 5.671 336 5.984 337 4.435 338 4.026 339 3.141 340 1.838 341 1.056 342 1.105 343 0.508 344 0.308 345 -0.354 346 -0.693 347 -0.371 348 -0.430 349 -0.508 350 0.118 351 0.023 352 -0.011 353 0.257 354 0.856 355 1.005 356 1.782 357 3.305 358 4.599 359 5.439 360 5.942 361 5.920 362 6.825 363 7.009 364 7.222 365 7.079 366 7.355 367 7.368 368 6.593 369 6.110 370 6.735 371 7.162 372 7.849 373 8.099 374 7.431 375 7.954 376 7.819 377 7.821 378 8.183 379 8.380 380 8.428 381 8.048 382 8.563 383 8.088 384 7.880 385 7.527 386 6.725 387 7.370 388 7.035 389 6.464 390 5.996 391 5.031 392 4.549 393 4.080 394 3.094 395 3.080 396 2.663 397 2.630 398 2.114 399 1.476 400 1.232 401 0.644 402 1.488 403 2.013 404 2.124 405 2.293 406 2.144 407 2.906 408 3.442 409 3.113 410 2.850 411 2.783 412 3.090 413 2.789 414 2.103 415 1.907 416 1.486 417 1.351 418 2.402 419 2.409 420 3.594 421 4.212 422 5.276 423 6.732 424 7.760 425 7.877 426 7.074 427 5.973 428 5.518 429 5.162 430 5.395 431 5.970 432 6.342 433 6.485 434 6.498 435 6.210 436 6.168 437 5.448 438 5.555 439 4.698 440 4.304 441 3.300 442 2.580 443 1.627 444 1.552 445 1.577 446 1.178 447 1.023 448 0.362 449 -0.313 450 -0.716 451 -0.569 452 -0.069 453 0.958 454 2.104 455 2.811 456 3.362 457 3.470 458 4.032 459 4.263 460 4.747 461 5.423 462 5.817 463 5.755 464 5.133 465 4.941 466 4.400 467 4.111 468 3.955 469 3.204 470 2.591 471 2.096 472 1.062 473 0.204 474 0.123 475 0.954 476 2.374 477 3.093 478 4.409 479 5.821 480 6.351 481 7.465 482 8.805 483 10.373 484 11.353 485 11.888 486 11.708 487 11.462 488 11.303 489 11.178 490 11.516 491 12.056 492 11.447 493 11.488 494 10.821 495 9.755 496 9.512 497 9.869 498 10.302 499 11.166 500 11.847 501 12.136 502 11.763 503 11.214 504 11.399 505 11.729 506 11.441 507 11.695 508 11.249 509 10.384 510 10.003 511 10.740 Predicted TOPCONS reliability (left column=sequence position; right column=reliability) 11 40.00 12 40.00 13 40.00 14 40.00 15 40.00 16 42.86 17 45.71 18 48.57 19 51.43 20 54.29 21 57.14 22 60.00 23 62.86 24 65.71 25 68.57 26 71.43 27 74.29 28 77.14 29 80.00 30 82.86 31 85.71 32 88.57 33 91.43 34 94.29 35 97.14 36 100.00 37 100.00 38 100.00 39 100.00 40 100.00 41 100.00 42 100.00 43 100.00 44 100.00 45 100.00 46 100.00 47 100.00 48 100.00 49 100.00 50 100.00 51 100.00 52 100.00 53 100.00 54 100.00 55 100.00 56 100.00 57 100.00 58 100.00 59 100.00 60 100.00 61 100.00 62 100.00 63 100.00 64 100.00 65 100.00 66 100.00 67 100.00 68 100.00 69 100.00 70 100.00 71 100.00 72 100.00 73 100.00 74 100.00 75 100.00 76 100.00 77 100.00 78 100.00 79 100.00 80 100.00 81 100.00 82 100.00 83 100.00 84 100.00 85 100.00 86 100.00 87 100.00 88 100.00 89 100.00 90 100.00 91 100.00 92 100.00 93 100.00 94 100.00 95 100.00 96 100.00 97 100.00 98 100.00 99 100.00 100 100.00 101 100.00 102 100.00 103 100.00 104 100.00 105 100.00 106 100.00 107 100.00 108 100.00 109 100.00 110 100.00 111 100.00 112 100.00 113 100.00 114 100.00 115 100.00 116 100.00 117 100.00 118 100.00 119 100.00 120 100.00 121 100.00 122 100.00 123 100.00 124 100.00 125 100.00 126 100.00 127 100.00 128 100.00 129 100.00 130 100.00 131 100.00 132 100.00 133 100.00 134 100.00 135 100.00 136 100.00 137 100.00 138 100.00 139 100.00 140 100.00 141 100.00 142 100.00 143 100.00 144 100.00 145 100.00 146 100.00 147 100.00 148 100.00 149 100.00 150 100.00 151 100.00 152 100.00 153 100.00 154 100.00 155 100.00 156 100.00 157 100.00 158 100.00 159 100.00 160 98.10 161 97.14 162 97.14 163 97.14 164 97.14 165 97.14 166 97.14 167 97.14 168 97.14 169 97.14 170 97.14 171 97.14 172 97.14 173 97.14 174 97.14 175 97.14 176 97.14 177 97.14 178 97.14 179 97.14 180 97.14 181 99.05 182 98.10 183 98.10 184 98.10 185 98.10 186 98.10 187 98.10 188 98.10 189 98.10 190 98.10 191 98.10 192 98.10 193 98.10 194 98.10 195 98.10 196 98.10 197 98.10 198 98.10 199 98.10 200 98.10 201 98.10 202 98.10 203 100.00 204 100.00 205 100.00 206 99.05 207 98.10 208 96.19 209 94.29 210 92.38 211 91.43 212 91.43 213 91.43 214 91.43 215 91.43 216 91.43 217 91.43 218 91.43 219 91.43 220 91.43 221 91.43 222 91.43 223 91.43 224 91.43 225 91.43 226 91.43 227 92.38 228 93.33 229 94.29 230 95.24 231 95.24 232 95.24 233 93.33 234 91.43 235 90.48 236 90.48 237 90.48 238 90.48 239 90.48 240 90.48 241 90.48 242 90.48 243 90.48 244 90.48 245 90.48 246 90.48 247 90.48 248 90.48 249 90.48 250 91.43 251 92.38 252 94.29 253 95.24 254 95.24 255 95.24 256 94.29 257 92.38 258 90.48 259 90.48 260 90.48 261 90.48 262 90.48 263 90.48 264 90.48 265 90.48 266 90.48 267 90.48 268 90.48 269 90.48 270 90.48 271 90.48 272 90.48 273 90.48 274 90.48 275 92.38 276 91.43 277 93.33 278 95.24 279 97.14 280 97.14 281 97.14 282 97.14 283 97.14 284 97.14 285 97.14 286 97.14 287 97.14 288 97.14 289 97.14 290 97.14 291 97.14 292 97.14 293 97.14 294 97.14 295 97.14 296 97.14 297 99.05 298 99.05 299 99.05 300 99.05 301 98.10 302 96.19 303 95.24 304 94.29 305 93.33 306 92.38 307 91.43 308 90.48 309 89.52 310 88.57 311 87.62 312 86.67 313 85.71 314 84.76 315 83.81 316 82.86 317 81.90 318 81.90 319 80.95 320 79.05 321 77.14 322 75.24 323 76.19 324 76.19 325 76.19 326 76.19 327 76.19 328 76.19 329 76.19 330 75.24 331 73.33 332 74.29 333 75.24 334 76.19 335 77.14 336 78.10 337 79.05 338 80.00 339 80.95 340 81.90 341 83.81 342 85.71 343 88.57 344 89.52 345 90.48 346 91.43 347 92.38 348 93.33 349 94.29 350 95.24 351 97.14 352 98.10 353 97.14 354 96.19 355 95.24 356 94.29 357 93.33 358 92.38 359 91.43 360 90.48 361 89.52 362 88.57 363 87.62 364 86.67 365 85.71 366 84.76 367 83.81 368 82.86 369 81.90 370 80.95 371 80.00 372 79.05 373 80.00 374 80.00 375 80.00 376 80.00 377 80.00 378 80.00 379 80.00 380 80.00 381 80.00 382 80.00 383 80.00 384 80.00 385 80.00 386 80.00 387 80.00 388 80.00 389 80.00 390 79.05 391 78.10 392 77.14 393 78.10 394 79.05 395 80.00 396 80.95 397 81.90 398 82.86 399 83.81 400 84.76 401 85.71 402 86.67 403 87.62 404 88.57 405 89.52 406 90.48 407 91.43 408 92.38 409 93.33 410 94.29 411 96.19 412 98.10 413 98.10 414 97.14 415 96.19 416 95.24 417 94.29 418 93.33 419 92.38 420 91.43 421 90.48 422 89.52 423 88.57 424 86.67 425 83.81 426 82.86 427 81.90 428 81.90 429 81.90 430 81.90 431 81.90 432 81.90 433 81.90 434 83.81 435 84.76 436 85.71 437 86.67 438 87.62 439 88.57 440 89.52 441 90.48 442 91.43 443 92.38 444 93.33 445 95.24 446 98.10 447 96.19 448 94.29 449 93.33 450 92.38 451 91.43 452 90.48 453 88.57 454 87.62 455 86.67 456 85.71 457 84.76 458 83.81 459 82.86 460 81.90 461 80.95 462 80.00 463 79.05 464 78.10 465 77.14 466 76.19 467 75.24 468 77.14 469 79.05 470 79.05 471 79.05 472 78.10 473 76.19 474 78.10 475 79.05 476 80.00 477 80.95 478 81.90 479 82.86 480 83.81 481 84.76 482 85.71 483 86.67 484 87.62 485 88.57 486 89.52 487 90.48 488 91.43 489 92.38 490 93.33 491 94.29 492 95.24 493 97.14 494 100.00 495 100.00 496 100.00 497 100.00 498 100.00 499 100.00 500 100.00 501 100.00 502 100.00 503 100.00 504 100.00 505 100.00 506 100.00 507 100.00 508 100.00 509 100.00 ##############################################################################