PredyFlexy software 1.3.1
The team
All developpements have done in DSIMB lab (Structural Dynamics and Interactions of Biological Macromolecules). DSIMB is a Bioinformatic Team devoted to different thematics (protein structure analysis, molecular modelling, molecular dynamics, protein docking, methodological developpements...). The team is directed by Pr. Catherine Etchebest. The unit is a mixed unit between French National Institute of Health and Medical Research (INSERM) and University Paris Diderot, we are located at the French National Institute of Institute of Blood Transfusion (INTS). We are the second team of INSERM UMR-S 1134 unit directed by Yves Colin.The people
Developpments on local protein conformations have begun under the guidance of Pr. Serge Hazout by Dr. Alexandre G. de Brevern with Pr. Catherine Etchebest [1]. The improvements of long structural prototypes (LSPs) prediction [2] and flexibility prediction was done by Dr. Aurelie Bornot during her PhD with Dr. Alexandre G. de Brevern and Pr. Catherine Etchebest [3]. Dr. Jean-Christophe Gelly and Dr. Pierrick Craveur, MSc participated with them to the proposition of a dedicated webserver [4]. This last version of the software was done with the extra help of Mr. Sylvain Leonard, MSc, Mr. Tarun J. Narwani, MSc and Dr. Joseph Rebehmed [5].Contact us
You can contact us, please change " ABC " by :"@" Alexandre.De-Brevern ABC inserm.fr for Alexandre G. de Brevern Catherine.Etchebest ABC inserm.fr for Catherine Etchebest Jean-Christophe.Gelly ABC inserm.fr for Jean-Christophe Gelly Pierre.Poulain ABC inserm.fr for Pierre Poulain tjrnarwani ABC gmail.com for Tarun J. Narwani rebehmed ABC gmail.com for Joseph Rebehmed Pierrick.Craveur ABC gmail.com for Pierrick.Craveur Sylvain.Leonard ABC inserm.fr for Sylvain LeonardSome other tools of DSIMB
- A prediction of Protein Blocks (Java) is proposed here : LocPred..
- iPBA (protein 3D structure superimposition and PDB mining).
- Protein Peeling 3 (assignment of Protein Units).
- Links to KAKSI (assignment of secondary structures). [a local page can be found here]
- PredyFlexy (prediction of protein flexibility).
- PBE (Protein Block Expert website).
For a complete list see DSIMB tool page
Some references
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de Brevern A.G. , Etchebest C., Hazout S.
Bayesian probabilistic approach for predicting backbone structures in terms of protein blocks
Proteins (2000) 41, 271-287
- Bornot A., Etchebest C., de Brevern A.G.
A new prediction strategy for long local protein structures using an original description
Proteins (2009) 76(3):570-87.
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Bornot A., Etchebest C., de Brevern A.G.
Predicting Protein Flexibility through the Prediction of Local Structures.
Proteins (2011)79(3):839-52.
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de Brevern A.G.*, Bornot A.*, Craveur P., Etchebest C., Gelly J.-C.
PredyFlexy: Flexibility and Local Structure prediction from sequence
Nucleic Acid Res (2012) 40:W317-22.
*: authors contribute equally.
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Narwani T.J.*.,Etchebest C.*, Craveur P., Leonard S., Rebehmed J., Bornot A., Gelly J.-C., de Brevern A.G.
in silico prediction of protein flexibility with local structure approach
submitted (2016) .
*: authors contribute equally.
Alexandre G. de Brevern
Last Modification : July 2016