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Human FLAP with an iodinated analog of MK-591

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF01124
PDB ID: 2Q7R


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 20.0 Å

Number of TM segments = 10

Sequence positions:
A: 12-25|56-69|87-100|109-119
C: 297-312|405-419
B: 159-176|192-214|226-243|251-268

Tilt angles:
A - Segment: 12-25 - Tilt: 14.2°
A - Segment: 56-69 - Tilt: 28.6°
A - Segment: 87-100 - Tilt: 33.8°
A - Segment: 109-119 - Tilt: 28.9°
C - Segment: 297-312 - Tilt: 45.1°
C - Segment: 405-419 - Tilt: 26.8°
B - Segment: 159-176 - Tilt: 52.1°
B - Segment: 192-214 - Tilt: 51.8°
B - Segment: 226-243 - Tilt: 48.3°
B - Segment: 251-268 - Tilt: 51.6°


Structural assessment:

MAIDEN score = -21.3220
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]