Connexin-26 gap junction channel at 3.5 Å resolution
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF00029
PDB ID: 2ZW3
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 38.0 Å
Number of TM segments = 24
Sequence positions:
A: 18-44|68-93|118-142|169-199
C: 420-446|470-495|520-548|571-601
B: 219-245|269-294|319-347|370-400
E: 822-849|872-897|922-950|972-1003
D: 621-648|671-696|721-749|771-802
F: 1023-1049|1073-1098|1123-1151|1174-1204
Tilt angles:
A - Segment: 18-44 - Tilt: 34.7°
A - Segment: 68-93 - Tilt: 9.5°
A - Segment: 118-142 - Tilt: 14.9°
A - Segment: 169-199 - Tilt: 33.7°
C - Segment: 420-446 - Tilt: 33.7°
C - Segment: 470-495 - Tilt: 10.5°
C - Segment: 520-548 - Tilt: 24.2°
C - Segment: 571-601 - Tilt: 33.4°
B - Segment: 219-245 - Tilt: 34.3°
B - Segment: 269-294 - Tilt: 10.2°
B - Segment: 319-347 - Tilt: 24.0°
B - Segment: 370-400 - Tilt: 33.6°
E - Segment: 822-849 - Tilt: 29.3°
E - Segment: 872-897 - Tilt: 9.4°
E - Segment: 922-950 - Tilt: 23.0°
E - Segment: 972-1003 - Tilt: 35.3°
D - Segment: 621-648 - Tilt: 29.1°
D - Segment: 671-696 - Tilt: 10.1°
D - Segment: 721-749 - Tilt: 23.7°
D - Segment: 771-802 - Tilt: 35.6°
F - Segment: 1023-1049 - Tilt: 34.0°
F - Segment: 1073-1098 - Tilt: 8.9°
F - Segment: 1123-1151 - Tilt: 22.7°
F - Segment: 1174-1204 - Tilt: 32.7°
Structural assessment:
MAIDEN score = -269.6223
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]