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P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Organism: Mus musculus
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00664
PDB ID: 3G5U


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 21.0 Å

Number of TM segments = 5

Sequence positions:
A: 184-212|322-364|612-695|845-873|948-989

Tilt angles:
A - Segment: 184-212 - Tilt: 60.0°
A - Segment: 322-364 - Tilt: 74.9°
A - Segment: 612-695 - Tilt: 75.9°
A - Segment: 845-873 - Tilt: 56.1°
A - Segment: 948-989 - Tilt: 48.5°


Structural assessment:

MAIDEN score = -21.4977
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]