P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Organism: Mus musculus
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF00664
PDB ID: 3G5U
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 20.4 Å
Number of TM segments = 12
Sequence positions:
A: 11-29|86-103|149-163|190-203|255-271|304-320|619-633|669-682|740-755|765-782|842-859|887-901
Tilt angles:
A - Segment: 11-29 - Tilt: 51.8°
A - Segment: 86-103 - Tilt: 42.1°
A - Segment: 149-163 - Tilt: 21.2°
A - Segment: 190-203 - Tilt: 22.2°
A - Segment: 255-271 - Tilt: 27.5°
A - Segment: 304-320 - Tilt: 37.7°
A - Segment: 619-633 - Tilt: 36.7°
A - Segment: 669-682 - Tilt: 18.3°
A - Segment: 740-755 - Tilt: 31.7°
A - Segment: 765-782 - Tilt: 44.1°
A - Segment: 842-859 - Tilt: 44.6°
A - Segment: 887-901 - Tilt: 37.5°
Structural assessment:
MAIDEN score = -25.3652
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]