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Human Aquaporin 4 at 1.8 and its Mechanism of Conductance

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00230
PDB ID: 3GD8


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 27.6 Å

Number of TM segments = 6

Sequence positions:
A: 35-55|71-89|112-133|157-177|186-205|230-248

Tilt angles:
A - Segment: 35-55 - Tilt: 33.6°
A - Segment: 71-89 - Tilt: 26.5°
A - Segment: 112-133 - Tilt: 41.1°
A - Segment: 157-177 - Tilt: 38.0°
A - Segment: 186-205 - Tilt: 25.4°
A - Segment: 230-248 - Tilt: 35.9°


Structural assessment:

MAIDEN score = -64.3774
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]