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Human Aquaporin 4 at 1.8 and its Mechanism of Conductance

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00230
PDB ID: 3GD8


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 30.6 Å

Number of TM segments = 6

Sequence positions:
A: 4-25|39-76|79-105|125-147|154-174|195-221

Tilt angles:
A - Segment: 4-25 - Tilt: 24.8°
A - Segment: 39-76 - Tilt: 33.3°
A - Segment: 79-105 - Tilt: 37.4°
A - Segment: 125-147 - Tilt: 31.4°
A - Segment: 154-174 - Tilt: 23.7°
A - Segment: 195-221 - Tilt: 42.7°


Structural assessment:

MAIDEN score = -71.6685
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]