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TRPV1 ion channel determined by single particle electron cryo-microscopy

Organism: Rattus norvegicus
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF06011
PDB ID: 3J5P


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 33.6 Å

Number of TM segments = 24

Sequence positions:
A: 915-937|954-979|985-1009|1013-1034|1042-1075|1109-1136
C: 1507-1529|1544-1571|1577-1601|1605-1626|1634-1667|1701-1728
B: 323-345|362-387|393-417|421-442|450-484|516-544
D: 2099-2121|2136-2163|2171-2193|2195-2218|2229-2260|2293-2320

Tilt angles:
A - Segment: 915-937 - Tilt: 16.5°
A - Segment: 954-979 - Tilt: 36.6°
A - Segment: 985-1009 - Tilt: 24.8°
A - Segment: 1013-1034 - Tilt: 28.6°
A - Segment: 1042-1075 - Tilt: 48.7°
A - Segment: 1109-1136 - Tilt: 40.1°
C - Segment: 1507-1529 - Tilt: 15.7°
C - Segment: 1544-1571 - Tilt: 36.6°
C - Segment: 1577-1601 - Tilt: 25.7°
C - Segment: 1605-1626 - Tilt: 28.4°
C - Segment: 1634-1667 - Tilt: 47.9°
C - Segment: 1701-1728 - Tilt: 39.2°
B - Segment: 323-345 - Tilt: 17.0°
B - Segment: 362-387 - Tilt: 35.8°
B - Segment: 393-417 - Tilt: 25.0°
B - Segment: 421-442 - Tilt: 29.5°
B - Segment: 450-484 - Tilt: 45.4°
B - Segment: 516-544 - Tilt: 37.1°
D - Segment: 2099-2121 - Tilt: 16.2°
D - Segment: 2136-2163 - Tilt: 35.8°
D - Segment: 2171-2193 - Tilt: 22.4°
D - Segment: 2195-2218 - Tilt: 30.6°
D - Segment: 2229-2260 - Tilt: 39.8°
D - Segment: 2293-2320 - Tilt: 39.6°


Structural assessment:

MAIDEN score = -266.2953
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]