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TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy

Organism: Rattus norvegicus
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF06011
PDB ID: 3J5Q


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 32.4 Å

Number of TM segments = 24

Sequence positions:
B: 915-936|954-979|987-1009|1013-1034|1042-1076|1109-1136
E: 1507-1528|1546-1571|1579-1601|1605-1626|1634-1668|1701-1728
D: 324-345|362-386|395-417|419-441|453-484|517-544
G: 2100-2121|2138-2163|2171-2193|2197-2217|2229-2260|2293-2320

Tilt angles:
B - Segment: 915-936 - Tilt: 14.3°
B - Segment: 954-979 - Tilt: 36.6°
B - Segment: 987-1009 - Tilt: 21.1°
B - Segment: 1013-1034 - Tilt: 29.2°
B - Segment: 1042-1076 - Tilt: 46.9°
B - Segment: 1109-1136 - Tilt: 39.2°
E - Segment: 1507-1528 - Tilt: 13.6°
E - Segment: 1546-1571 - Tilt: 37.9°
E - Segment: 1579-1601 - Tilt: 20.4°
E - Segment: 1605-1626 - Tilt: 27.8°
E - Segment: 1634-1668 - Tilt: 45.9°
E - Segment: 1701-1728 - Tilt: 38.4°
D - Segment: 324-345 - Tilt: 12.6°
D - Segment: 362-386 - Tilt: 38.3°
D - Segment: 395-417 - Tilt: 22.3°
D - Segment: 419-441 - Tilt: 34.2°
D - Segment: 453-484 - Tilt: 40.9°
D - Segment: 517-544 - Tilt: 38.1°
G - Segment: 2100-2121 - Tilt: 11.3°
G - Segment: 2138-2163 - Tilt: 38.3°
G - Segment: 2171-2193 - Tilt: 21.7°
G - Segment: 2197-2217 - Tilt: 32.3°
G - Segment: 2229-2260 - Tilt: 40.0°
G - Segment: 2293-2320 - Tilt: 37.3°


Structural assessment:

MAIDEN score = -254.8751
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]