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CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00001
PDB ID: 3OE0


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 35.7 Å

Number of TM segments = 6

Sequence positions:
A: 16-40|45-70|73-107|128-150|156-199|367-394

Tilt angles:
A - Segment: 16-40 - Tilt: 4.2°
A - Segment: 45-70 - Tilt: 29.6°
A - Segment: 73-107 - Tilt: 45.9°
A - Segment: 128-150 - Tilt: 30.8°
A - Segment: 156-199 - Tilt: 55.9°
A - Segment: 367-394 - Tilt: 39.9°


Structural assessment:

MAIDEN score = -41.0393
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]