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Human M2 muscarinic acetylcholine receptor bound to an antagonist

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00001
PDB ID: 3UON


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 35.1 Å

Number of TM segments = 7

Sequence positions:
A: 24-47|61-84|91-118|144-171|176-207|388-414|419-443

Tilt angles:
A - Segment: 24-47 - Tilt: 6.9°
A - Segment: 61-84 - Tilt: 5.8°
A - Segment: 91-118 - Tilt: 35.8°
A - Segment: 144-171 - Tilt: 12.0°
A - Segment: 176-207 - Tilt: 39.4°
A - Segment: 388-414 - Tilt: 27.7°
A - Segment: 419-443 - Tilt: 22.0°


Structural assessment:

MAIDEN score = -105.4748
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]