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Human M2 muscarinic acetylcholine receptor bound to an antagonist

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00001
PDB ID: 3UON


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 33.0 Å

Number of TM segments = 7

Sequence positions:
A: 4-26|42-65|71-100|124-148|164-191|369-391|403-425

Tilt angles:
A - Segment: 4-26 - Tilt: 18.4°
A - Segment: 42-65 - Tilt: 18.5°
A - Segment: 71-100 - Tilt: 42.2°
A - Segment: 124-148 - Tilt: 27.4°
A - Segment: 164-191 - Tilt: 35.8°
A - Segment: 369-391 - Tilt: 22.2°
A - Segment: 403-425 - Tilt: 14.2°


Structural assessment:

MAIDEN score = -75.9008
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]