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Human adenosine A2A receptor with an allosteric inverse-agonist antibody at 3.1 Å resolution

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00001
PDB ID: 3VGA


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 28.0 Å

Number of TM segments = 7

Sequence positions:
A: 7-26|35-55|78-99|114-132|169-191|217-235|263-280

Tilt angles:
A - Segment: 7-26 - Tilt: 22.2°
A - Segment: 35-55 - Tilt: 28.2°
A - Segment: 78-99 - Tilt: 37.6°
A - Segment: 114-132 - Tilt: 4.8°
A - Segment: 169-191 - Tilt: 35.2°
A - Segment: 217-235 - Tilt: 12.1°
A - Segment: 263-280 - Tilt: 11.6°


Structural assessment:

MAIDEN score = -54.2216
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]