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Human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 Å

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00001
PDB ID: 3VW7


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 21.0 Å

Number of TM segments = 6

Sequence positions:
A: 29-41|45-60|94-114|124-140|178-205|367-383

Tilt angles:
A - Segment: 29-41 - Tilt: 9.5°
A - Segment: 45-60 - Tilt: 29.8°
A - Segment: 94-114 - Tilt: 53.2°
A - Segment: 124-140 - Tilt: 41.2°
A - Segment: 178-205 - Tilt: 62.3°
A - Segment: 367-383 - Tilt: 42.6°


Structural assessment:

MAIDEN score = -32.9043
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]