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Human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF02932
PDB ID: 4COF


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 27.0 Å

Number of TM segments = 20

Sequence positions:
A: 227-244|246-262|285-303|423-442
C: 228-244|246-262|286-304|423-441
B: 228-244|246-262|286-303|423-441
E: 227-244|246-262|285-304|423-441
D: 228-244|246-262|286-304|423-441

Tilt angles:
A - Segment: 227-244 - Tilt: 22.7°
A - Segment: 246-262 - Tilt: 19.7°
A - Segment: 285-303 - Tilt: 18.7°
A - Segment: 423-442 - Tilt: 19.1°
C - Segment: 228-244 - Tilt: 14.6°
C - Segment: 246-262 - Tilt: 17.2°
C - Segment: 286-304 - Tilt: 14.7°
C - Segment: 423-441 - Tilt: 22.4°
B - Segment: 228-244 - Tilt: 13.6°
B - Segment: 246-262 - Tilt: 20.0°
B - Segment: 286-303 - Tilt: 17.4°
B - Segment: 423-441 - Tilt: 24.5°
E - Segment: 227-244 - Tilt: 24.3°
E - Segment: 246-262 - Tilt: 16.9°
E - Segment: 285-304 - Tilt: 22.4°
E - Segment: 423-441 - Tilt: 26.8°
D - Segment: 228-244 - Tilt: 17.5°
D - Segment: 246-262 - Tilt: 15.1°
D - Segment: 286-304 - Tilt: 17.0°
D - Segment: 423-441 - Tilt: 24.0°


Structural assessment:

MAIDEN score = -197.1953
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]