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Human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF02932
PDB ID: 4COF


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 22.0 Å

Number of TM segments = 15

Sequence positions:
A: 218-233|256-269|277-292
C: 880-895|918-931|939-953
B: 549-564|587-600|608-622
E: 1543-1559|1581-1594|1602-1617
D: 1211-1226|1249-1262|1270-1285

Tilt angles:
A - Segment: 218-233 - Tilt: 20.5°
A - Segment: 256-269 - Tilt: 17.5°
A - Segment: 277-292 - Tilt: 22.7°
C - Segment: 880-895 - Tilt: 20.7°
C - Segment: 918-931 - Tilt: 18.5°
C - Segment: 939-953 - Tilt: 22.0°
B - Segment: 549-564 - Tilt: 20.8°
B - Segment: 587-600 - Tilt: 18.1°
B - Segment: 608-622 - Tilt: 21.5°
E - Segment: 1543-1559 - Tilt: 15.0°
E - Segment: 1581-1594 - Tilt: 17.8°
E - Segment: 1602-1617 - Tilt: 23.0°
D - Segment: 1211-1226 - Tilt: 20.4°
D - Segment: 1249-1262 - Tilt: 18.7°
D - Segment: 1270-1285 - Tilt: 23.7°


Structural assessment:

MAIDEN score = -94.6008
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]