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Human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00002
PDB ID: 4K5Y


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 34.8 Å

Number of TM segments = 6

Sequence positions:
A: 37-63|70-105|270-294|311-342|352-375|378-405

Tilt angles:
A - Segment: 37-63 - Tilt: 38.7°
A - Segment: 70-105 - Tilt: 48.8°
A - Segment: 270-294 - Tilt: 26.5°
A - Segment: 311-342 - Tilt: 44.3°
A - Segment: 352-375 - Tilt: 21.0°
A - Segment: 378-405 - Tilt: 31.2°


Structural assessment:

MAIDEN score = -75.0981
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]