P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Organism: Mus musculus
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00664
PDB ID: 4KSB
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 24.9 Å
Number of TM segments = 12
Sequence positions:
A: 40-65|117-136|181-200|214-228|291-307|332-352|711-728|753-769|830-849|851-871|931-952|972-987
Tilt angles:
A - Segment: 40-65 - Tilt: 45.7°
A - Segment: 117-136 - Tilt: 32.3°
A - Segment: 181-200 - Tilt: 25.8°
A - Segment: 214-228 - Tilt: 17.0°
A - Segment: 291-307 - Tilt: 10.6°
A - Segment: 332-352 - Tilt: 42.3°
A - Segment: 711-728 - Tilt: 24.8°
A - Segment: 753-769 - Tilt: 4.0°
A - Segment: 830-849 - Tilt: 33.5°
A - Segment: 851-871 - Tilt: 48.5°
A - Segment: 931-952 - Tilt: 48.8°
A - Segment: 972-987 - Tilt: 12.1°
Structural assessment:
MAIDEN score = -66.7646
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]