P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Organism: Mus musculus
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00664
PDB ID: 4KSC
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 28.0 Å
Number of TM segments = 12
Sequence positions:
A: 43-68|114-135|182-204|210-228|292-310|329-348|708-729|751-770|829-849|851-872|928-952|971-988
Tilt angles:
A - Segment: 43-68 - Tilt: 49.5°
A - Segment: 114-135 - Tilt: 36.7°
A - Segment: 182-204 - Tilt: 36.5°
A - Segment: 210-228 - Tilt: 20.0°
A - Segment: 292-310 - Tilt: 21.4°
A - Segment: 329-348 - Tilt: 33.3°
A - Segment: 708-729 - Tilt: 36.7°
A - Segment: 751-770 - Tilt: 14.2°
A - Segment: 829-849 - Tilt: 24.8°
A - Segment: 851-872 - Tilt: 37.3°
A - Segment: 928-952 - Tilt: 45.4°
A - Segment: 971-988 - Tilt: 7.9°
Structural assessment:
MAIDEN score = -83.2296
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]