P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Organism: Mus musculus
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00664
PDB ID: 4KSD
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 26.0 Å
Number of TM segments = 12
Sequence positions:
A: 44-68|117-135|183-204|210-228|290-309|330-348|707-725|754-772|827-846|854-874|929-949|973-990
Tilt angles:
A - Segment: 44-68 - Tilt: 48.8°
A - Segment: 117-135 - Tilt: 24.7°
A - Segment: 183-204 - Tilt: 39.7°
A - Segment: 210-228 - Tilt: 22.9°
A - Segment: 290-309 - Tilt: 26.7°
A - Segment: 330-348 - Tilt: 19.6°
A - Segment: 707-725 - Tilt: 39.6°
A - Segment: 754-772 - Tilt: 25.1°
A - Segment: 827-846 - Tilt: 18.2°
A - Segment: 854-874 - Tilt: 33.9°
A - Segment: 929-949 - Tilt: 37.7°
A - Segment: 973-990 - Tilt: 8.7°
Structural assessment:
MAIDEN score = -101.0735
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]