Dopamine transporter elucidates antidepressant mechanism
Organism: Drosophila melanogaster
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00209
PDB ID: 4M48
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 25.0 Å
Number of TM segments = 10
Sequence positions:
A: 38-54|63-81|112-139|232-251|264-282|307-325|345-363|405-426|521-542|554-570
Tilt angles:
A - Segment: 38-54 - Tilt: 21.5°
A - Segment: 63-81 - Tilt: 27.2°
A - Segment: 112-139 - Tilt: 59.8°
A - Segment: 232-251 - Tilt: 36.2°
A - Segment: 264-282 - Tilt: 28.7°
A - Segment: 307-325 - Tilt: 40.1°
A - Segment: 345-363 - Tilt: 23.7°
A - Segment: 405-426 - Tilt: 48.4°
A - Segment: 521-542 - Tilt: 44.6°
A - Segment: 554-570 - Tilt: 18.5°
Structural assessment:
MAIDEN score = -73.4065
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]