Reverse polarity of binding pocket suggests different function of a MOP superfamily transporter from Pyrococcus furiosus Vc1 (DSM3638)
Organism: Pyrococcus furiosus
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF01554
PDB ID: 4MLB
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 26.1 Å
Number of TM segments = 22
Sequence positions:
A: 23-41|60-78|89-107|142-159|165-184|195-216|224-257|275-298|327-349|417-441
C: 475-493|510-527|551-569|589-609|620-639|647-663|693-710|734-751|771-792|819-838|841-858|880-897
Tilt angles:
A - Segment: 23-41 - Tilt: 27.3°
A - Segment: 60-78 - Tilt: 28.9°
A - Segment: 89-107 - Tilt: 16.2°
A - Segment: 142-159 - Tilt: 25.3°
A - Segment: 165-184 - Tilt: 32.7°
A - Segment: 195-216 - Tilt: 41.5°
A - Segment: 224-257 - Tilt: 57.3°
A - Segment: 275-298 - Tilt: 48.0°
A - Segment: 327-349 - Tilt: 37.5°
A - Segment: 417-441 - Tilt: 49.1°
C - Segment: 475-493 - Tilt: 29.7°
C - Segment: 510-527 - Tilt: 23.3°
C - Segment: 551-569 - Tilt: 15.1°
C - Segment: 589-609 - Tilt: 28.8°
C - Segment: 620-639 - Tilt: 33.1°
C - Segment: 647-663 - Tilt: 6.2°
C - Segment: 693-710 - Tilt: 22.4°
C - Segment: 734-751 - Tilt: 13.6°
C - Segment: 771-792 - Tilt: 36.7°
C - Segment: 819-838 - Tilt: 38.8°
C - Segment: 841-858 - Tilt: 21.6°
C - Segment: 880-897 - Tilt: 24.9°
Structural assessment:
MAIDEN score = -145.3382
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]