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Active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00001
PDB ID: 4MQS


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 35.0 Å

Number of TM segments = 7

Sequence positions:
A: 24-47|61-85|89-118|144-171|175-207|383-412|420-443

Tilt angles:
A - Segment: 24-47 - Tilt: 3.7°
A - Segment: 61-85 - Tilt: 14.5°
A - Segment: 89-118 - Tilt: 31.8°
A - Segment: 144-171 - Tilt: 13.2°
A - Segment: 175-207 - Tilt: 39.6°
A - Segment: 383-412 - Tilt: 41.3°
A - Segment: 420-443 - Tilt: 18.2°


Structural assessment:

MAIDEN score = -88.6908
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]