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Human Smoothened Receptor structure in complex with cyclopamine

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF01534
PDB ID: 4O9R


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 37.0 Å

Number of TM segments = 7

Sequence positions:
A: 229-254|263-287|312-340|358-381|397-424|451-475|514-538

Tilt angles:
A - Segment: 229-254 - Tilt: 23.7°
A - Segment: 263-287 - Tilt: 29.2°
A - Segment: 312-340 - Tilt: 38.2°
A - Segment: 358-381 - Tilt: 3.2°
A - Segment: 397-424 - Tilt: 24.1°
A - Segment: 451-475 - Tilt: 24.3°
A - Segment: 514-538 - Tilt: 21.0°


Structural assessment:

MAIDEN score = -100.1170
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]