Human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00003
PDB ID: 4OO9
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 35.7 Å
Number of TM segments = 7
Sequence positions:
A: 578-605|614-636|645-667|690-714|737-759|771-795|798-823
Tilt angles:
A - Segment: 578-605 - Tilt: 31.1°
A - Segment: 614-636 - Tilt: 15.9°
A - Segment: 645-667 - Tilt: 17.7°
A - Segment: 690-714 - Tilt: 21.0°
A - Segment: 737-759 - Tilt: 13.6°
A - Segment: 771-795 - Tilt: 14.5°
A - Segment: 798-823 - Tilt: 30.1°
Structural assessment:
MAIDEN score = -106.3473
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]